4 results about "Silver nanorods" patented technology

Provided are a Surface-Enhanced Raman Scattering (SERS) biosensor based on a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / Cas13a system and an application thereof, belonging to the field of spectroscopy detection. The SERS biosensor includes an SERS sensor chip, a first reagent, a second reagent, a third reagent, and a fourth reagent. The SERS sensor chip is a silver nanorod array substrate with hairpin Deoxyribonucleic Acid (DNA) single-stranded H1 and blocking molecule 6-mercaptoethanol modified on the surface. The first reagent is a SERS probe and buffer of the probe. The second reagent is hairpin nucleic acid aptamer strand MUC1-apt aqueous solution. The third reagent is the CRISPR / Cas13a system and buffer of the system. The fourth reagent is hairpin DNA single-stranded H2 aqueous solution. The above reagents are mixed with the gastric cancer exosomes to be detected and then dripped on a surface of the SERS sensor chip.

A photoelectric conversion element including a thin film composed of a transition metal dichalcogenide and formed on a base material. In the present invention, a surface of the thin film composed of the transition metal dichalcogenide is modified with at least any nanorod particles of Au nanorod particles composed of Au and Ag nanorod particles composed of Ag. An average aspect ratio of the Au nanorod particles is 3.0 or more and 12.0 or less, and an average aspect ratio of the Ag nanorod particles is 3.0 or more and 13.0 or less. In the invention, the sensitivity to light having wavelengths in the near-infrared region improves by a sensitizing action attributed to localized surface plasmon resonance that is developed by the Au and Ag nanorod particles.

This invention discloses a full-cycle photothermal-magnetic responsive intelligent antibacterial system based on silver nanorods combined with mesoporous iron(III) oxide and an antibacterial agent, its preparation method, and its application. Specifically: 1) Silver nanorods (AgNRs) are prepared using a solvothermal method, and used as the core. A mesoporous iron(III) oxide (MesoFe3O4) shell is constructed on their surface using a template method to obtain AgNRs@MesoFe3O4 material; 2) The antibacterial agent is loaded into the material in step 1 using a cyclic ultrasonic impregnation-low temperature air drying process; 3) A PBS solution of the AgNRs@MesoFe3O4 material loaded with the antibacterial agent is prepared, and after treatment, a full-cycle photothermal-magnetic responsive intelligent antibacterial system is obtained. The antibacterial system can achieve biofilm destruction and antibacterial agent release through external magnetic field driving and infrared light dual response. The AgNRs in the antibacterial system maintain a long-term antibacterial environment by slowly releasing silver ions, thus achieving full-cycle antibacterial activity.

This invention discloses a silver nanorod@mesoporous iron(III) oxide composite heterogeneous hydrogel material with bone-promoting and intelligent anti-infection functions, its preparation method, and its application. Specifically: 1) AgNRs are prepared, and a MesoFe3O4 shell is constructed on their surface using a template method to obtain AgNRs@MesoFe3O4; 2) Antibacterial agents are loaded into AgNRs@MesoFe3O4 using cyclic ultrasonic impregnation-low-temperature vacuum drying; 3) A sodium alginate solution containing drug-loaded AgNRs@MesoFe3O4 is poured into the bottom layer of a mold to obtain a nanomaterial layer, and a mixed solution containing AlgMA and sodium alginate is poured into the top layer; 4) UV curing and Ca2+ curing are performed. 2+ The solution impregnation method achieves dual in-situ gelation of the above solution. The solution is impregnated in a solution containing osteogenic drugs, rinsed, dried, and sterilized by irradiation to obtain a heterogeneous hydrogel. This material disrupts biofilms and kills bacteria, exhibiting both antibacterial and osteogenic functions.