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Method of treating bleeding in a patient having a tendency to bleed

A technology for patients and leukemia, applied in blood diseases, extracellular fluid diseases, liquid delivery, etc., can solve problems such as consumption

Inactive Publication Date: 2017-12-12
理查德·C·K·延
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, giving prophylactic platelet transfusions cannot prevent such bleeding, so the patient's internal crisis will continue to consume the transfused platelets, resulting in clinical bleeding shortly after the so-called prophylactic transfusion

Method used

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Examples

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Embodiment Construction

[0006] Although specific embodiments of the invention and cases of patients treated will now be described, it should be understood that such embodiments are by way of example only, and merely illustrative of the many possible applications which can only represent the principles of the invention. A small part of the detailed description. Various changes and modifications apparent to those skilled in the art to which the present invention pertains are deemed to be within the spirit, scope and intent of the present invention as further defined in the claims or appended claims.

[0007] The manufacture of fibrinogen-coated and non-fibrinogen-coated albumin spheres of medicinal value has been widely disclosed by Dr. Richard C.K. Yen and his works. For example, U.S. Patent No. 5069936 "Manufacturing Protein Microspheres" (Dec. 3, 1991); U.S. Patent No. 9351925 "Submicron Particles for Reducing Blood Transfusion" (May 31, 2016); Large-scale production of ready-to-use suspensions of ...

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Abstract

The present invention provides a method of treating bleeding in a patient having a tendency to bleed, wherein the method of treatment will reduce the severity of bleeding, the method comprising: administering the dosage at a dosage sufficient to reduce the severity of bleeding in the patient, Frequency Intravenous administration of fibrinogen-coated albumin spheres. The present invention also provides a product for treating bleeding or reducing bleeding, comprising fibrinogen-coated albumin spheres having a diameter in the range of 50 to 500 nanometers and a median diameter of about 140 to 160 nanometers. The products and methods of treatment of the present invention are better able to reduce the severity of bleeding and the amount of bleeding.

Description

technical field [0001] The present invention relates to treatments for controlling or reducing bleeding in blood disease patients and cancer patients. These patients are prone to bleeding due to their disease condition or due to treatment for a hematological or cancer disorder (eg, chemotherapy that produces or increases the likelihood of bleeding). The treatment may be prophylactic or therapeutic, with prophylactic treatment referring to treatment given prior to any active clinical or subclinical bleeding, and therapeutic treatment referring to treatment given when the patient is actively bleeding. Background technique [0002] There are many types of blood disease patients or cancer patients. Since platelet function and platelet concentration in the body are known to be the main predictors of bleeding, many studies have been conducted to evaluate how low a platelet concentration should be given to a patient for prophylactic platelet transfusion, in the hope that the patie...

Claims

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Application Information

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IPC IPC(8): A61K38/36A61K9/10A61K9/19A61K9/16A61K47/42A61P7/04
CPCA61K9/0019A61K9/10A61K9/1658A61K9/19A61K38/363
Inventor 理查德·C·K·延
Owner 理查德·C·K·延
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