Anti-interference electrochemical sensor and testing method thereof

A sensor, electrochemical technology, applied in the direction of electrochemical variables of materials, etc., can solve the problems of complex electrode processing technology, and achieve the effect of completely eliminating interference, simple electrode structure, and good linear relationship.

Inactive Publication Date: 2018-01-05
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although the above methods have a certain effect on the interference elimination of electrochemical sensors, there are disadvantages such as a single method can only eliminate part of the interference, and the electrode processing process is complicated.

Method used

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  • Anti-interference electrochemical sensor and testing method thereof
  • Anti-interference electrochemical sensor and testing method thereof
  • Anti-interference electrochemical sensor and testing method thereof

Examples

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Embodiment Construction

[0019] The present invention will be described in detail below in conjunction with the accompanying drawings.

[0020] Such as figure 1 As shown, as an implementation, the anti-interference electrochemical sensor of the present invention may include an electrode substrate 100 , an insulating substrate 200 and an insulating cover 300 . A working electrode 101 and a reference electrode 102 are disposed on the electrode substrate 100 . A sample hole 201 is opened on the insulating substrate 200 . The insulating substrate 200 is fixed on the electrode substrate 100, so that the sample hole 201 can contain the sample solution to be tested. The sample hole 201 matches the working electrode 101 and the reference electrode 102 , so that the sample solution to be tested in the sample hole 201 can contact the working electrode 101 and the reference electrode 102 . The biochemical reagent 301 is coated on the insulating cover 300 . The insulating cover 300 can be movably connected to...

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Abstract

The invention discloses an anti-interference electrochemical sensor and a testing method thereof. The anti-interference electrochemical sensor comprises an electrode substrate and an insulating substrate and also comprises an insulating cover plate, wherein a working electrode and a reference electrode are arranged on the electrode substrate, a sample hole is formed in the insulating substrate, and the insulating cover plate is coated with a biological chemical reagent. During testing, an interferent in a sample solution to be tested is firstly consumed on the working electrode, then the biological chemical reagent produces chemical reaction with a target analyte in the sample solution to be tested through contact between the biological chemical reagent on the insulating cover plate and the sample solution to be tested, a reaction product is generated and produces electrochemical reaction on the working electrode, accordingly the interferent and an electrochemical current signal of thereaction product are separated in time, and the anti-interference purpose is achieved.

Description

technical field [0001] The present invention relates to an electrochemical sensor for determining the concentration of a target analyte in a liquid sample. Background technique [0002] Electrochemical sensors are applied to the determination of the concentration of target analytes in liquid samples, among which electrochemical biosensors based on enzyme biomolecules are one of the most widely used electrochemical sensors, commercialized blood glucose, blood ketones, blood lipids and blood creatinine Electrochemical sensors belong to this type of sensor. This type of sensor usually immobilizes enzyme biomolecules on the working electrode, and realizes the quantitative determination of the target analyte by detecting the enzyme-catalyzed oxidation or reduction current of the target analyte. [0003] However, liquid samples often contain chemical substances other than target analytes, such as paracetamol, ascorbic acid, bilirubin, dopamine, gentisic acid, levodopa, uric acid,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/26
Inventor 梁波曹庆朋叶学松
Owner ZHEJIANG UNIV
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