Pharmaceutical composition containing radix angelicae and application thereof
A composition and the technology of Angelica dahurica extract, which are applied in the direction of drug combination, medical preparations containing active ingredients, active ingredients of hydroxyl compounds, etc., can solve problems such as many adverse reactions, low effective rate, and delayed onset time
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preparation example 1
[0126] Preparation Example 1: Preparation of Radix Angelicae Radix Extract (extract)
[0127] 2 kg of Angelica dahurica (root medicine) is crushed, soaked in 85% ethanol solution (1:10, w:v) for 24 hours, then ultrasonically extracted for 1 hour, during which time it is shaken every 15 minutes, and the extraction temperature is 25°C. Collect the first extract. Under the same conditions, the second and third extractions were carried out respectively from the solid medicinal dregs. Combine the 3 extracts and discard the dregs.
[0128] The combined extracts were concentrated under reduced pressure to obtain 150 g of extract.
[0129] Extraction rate = 150g / 2000g = 7.5%.
preparation example 2
[0130] Preparation Example 2: Preparation of Angelica Radix Extract-borneol composition
[0131] The extraction method of Angelica dahurica extract is the same as the previous preparation example 1.
[0132] Grind the borneol into a powder, mix it with the extract of Angelica dahurica before use and dissolve it in 0.5% CMC-Na, and make a prescription of borneol: Angelica dahurica according to the mass ratio of medicinal materials 1:180.
preparation example 3
[0133] Preparation example 3: Preparation of Angelica dahurica-Chuanxiong extract (extract)
[0134] Angelica dahurica 1kg, Chuanxiong 0.6kg, mixed and crushed, soaked in 85% ethanol (1:10, w:v) for 24 hours. Then ultrasonically extract for 1 hour, shake well once every 15 minutes, and extract at 25°C. Collect the first extract. Under the same conditions, the second and third extractions were carried out respectively from the solid medicinal dregs. Combine 3 times of ultrasonic ethanol extracts, and discard drug residues.
[0135] The combined extracts were concentrated under reduced pressure to obtain 111 g of extract.
[0136] Extraction rate=111g / 1600g=6.9%.
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