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Externally-used ointment for treating skin diseases of pets and preparation method thereof

A technology for skin diseases and pets, which is applied in the field of topical ointment for pet skin diseases and its preparation, can solve the problem of low activity, and achieve the effect of simple steps, favorable for large-scale production and preparation, and simple operation

Inactive Publication Date: 2018-02-02
FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although many components with physiological activity have been found in Solidago canadensis, the existing studies only prove that it has a certain physiological activity, and there is no use of the plant extract to treat skin diseases in pets. In addition, although the extract of Solidago canadensis has certain antibacterial activity, it still has shortcomings such as low activity as a fungicide

Method used

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  • Externally-used ointment for treating skin diseases of pets and preparation method thereof
  • Externally-used ointment for treating skin diseases of pets and preparation method thereof
  • Externally-used ointment for treating skin diseases of pets and preparation method thereof

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preparation example Construction

[0041] The operation steps of the preparation method of the ointment for external use of the present invention are also relatively simple, and all components are classified and mixed.

[0042] Further preferably, different addition sequences can be further adopted, and the preparation of the external ointment of the present invention can be carried out with reference to the following three methods:

[0043] (I):

[0044] (a) After mixing the thickener, heat until completely dissolved, and stir evenly to obtain a thickener mixed system;

[0045] Preferably, in this step, the heating temperature is 60-70°C, more preferably, the heating temperature is 65°C, and preferably kept at the heating temperature;

[0046] (b) adding the emulsifier into the heated water, stirring and dissolving, then adding metronidazole, peppermint oil and Solidago sativa extract, stirring and dissolving;

[0047] Preferably, the heating temperature of the water is 70-85°C; more preferably, the heating ...

Embodiment 1

[0075] According to the percentage by mass: ketoconazole 1%, metronidazole 2%, peppermint oil 1%, cloverleaf essential oil 35%, thickener 5%, emulsifier 5%, and the rest of water, weigh the appropriate amount of each raw material;

[0076] Wherein, the thickener is a mixture of glyceryl monostearate, stearyl alcohol, petrolatum, liquid paraffin, vitamin E oil, isopropyl myristate;

[0077] Described emulsifying agent is sodium lauryl sulfate;

[0078] Then, prepare the external ointment of embodiment 1 according to the following method:

[0079] (a) Mix and heat glyceryl monostearate, stearyl alcohol, vaseline, liquid paraffin, vitamin E oil, and isopropyl myristate to 65°C. After the raw materials are completely dissolved, stir evenly to obtain a thickener mixture system, and keep it warm at 65°C;

[0080] (b) adding sodium lauryl sulfate into water at 80° C. and stirring to dissolve, then adding metronidazole, peppermint oil, and cloverleaf essential oil, stirring to diss...

Embodiment 2

[0084] According to mass percentage: ketoconazole 1%, metronidazole 2%, peppermint oil 1%, solidago volatile oil 40%, thickener 6%, emulsifier 6%, and the rest of water, weigh appropriate amount of each raw material ;

[0085] Wherein, the thickener is glyceryl monostearate, stearyl alcohol, vaseline, liquid paraffin, vitamin E oil, and isopropyl myristate;

[0086] The emulsifier is Tween-80 and Span-80;

[0087] Then, prepare the external ointment of embodiment 2 according to the following method:

[0088] (a) Mix Tween-80, Span-80, glyceryl monostearate, stearyl alcohol, vaseline, liquid paraffin, vitamin E oil, and isopropyl myristate and heat to 65°C until the ingredients are completely dissolved Finally, stir evenly to obtain a thickener mixed system;

[0089] (b) add metronidazole, peppermint oil and cloverleaf essential oil into water at 80°C, stir and dissolve, and keep warm at 80°C;

[0090] (c) After heating an appropriate amount of dilute hydrochloric acid to 6...

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Abstract

The invention provides an externally-used ointment for treating skin diseases of pets and a preparation method thereof. The externally-used ointment for treating the skin diseases of the pets comprises ketoconazole, metronidazole, peppermint oil, Solidago decurrens extract and auxiliary materials as raw material components, and through the compounding action among the components, a good pet skin disease treatment effect can be achieved. Meanwhile, the preparation method has the advantages of simple process steps and simple operation and is suitable for industrialized scale production.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to an external ointment for treating skin diseases of pets and a preparation method thereof. Background technique [0002] With the improvement of modern people's living standards, raising pets has become a way of leisure and can also be used as a spiritual sustenance. However, while accompanying people, the germs carried by pets can also endanger people's health. In addition to the well-known rabies, pet skin diseases can sometimes be transmitted to humans, such as tinea capitis, psoriasis, papular urticaria or prurigo, allergic dermatitis, and cryptococcal neoformans infection. [0003] Solidago canadensis (Solidago canadensis) is native to North America and is a perennial herb of the genus Solidago in the Asteraceae family. Introduced into my country as a flower plant in 1935, it was first cultivated in Shanghai and Nanjing, and later grew wild. Solidago canadensis reproduce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K9/06A61P17/00A61P31/10A61K31/496A61K31/4164
CPCA61K9/0014A61K9/06A61K31/4164A61K31/496A61K36/28A61K36/534A61K47/22A61K47/26A61K2300/00
Inventor 寇贺红陶映娴马静蓉付良凯孙迎
Owner FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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