Qi-invigorating and collapse-ascending pill and preparation method thereof

A technique for nourishing qi and weight, applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as being unsuitable for industrial application, requiring large-scale equipment, etc., to improve the left ventricular short-axis contraction rate, Improved safety and high content of active ingredients

Inactive Publication Date: 2018-03-23
GUANGDONG SANLAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, some new extraction methods have appeared, such as microwave, supercritical extractant ultrasonic, etc., due to the enhanced internal transfer process, extraction can be performed at lower temperatures, but it requires large-scale equipment and is not suitable for large-scale industrial applications

Method used

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  • Qi-invigorating and collapse-ascending pill and preparation method thereof
  • Qi-invigorating and collapse-ascending pill and preparation method thereof
  • Qi-invigorating and collapse-ascending pill and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1 Preparation of Yiqi Shengxian Pills

[0028] The Yiqi Shengxian Pill of Example 1 is prepared from the following raw materials:

[0029] There are 525 parts of Astragalus, 286 parts of Anemarrhena, 132 parts of Platycodon, 128 parts of Bupleurum and 76 parts of Cimicifuga.

[0030] Preparation:

[0031] (1) Take Astragalus, Anemarrhena, Platycodon grandiflorum, Bupleurum and Cimicifuga, wash, dry, crush into coarse powder, and set aside;

[0032] (2) Pour carbon dioxide into the above coarse powder, pressurize to 40MP under normal temperature conditions, expand for 10 minutes, release the pressure instantly, and obtain material A;

[0033] (3) Mix the above-mentioned material A with the mixed solvent, add an appropriate amount of zinc sulfate, the addition amount of zinc sulfate is 0.3% (w / w) of the weight of material A, and expose it to the high-voltage pulse electromagnetic field for 12 minutes under normal temperature conditions. Chinese medicine extract; wherein, th...

Embodiment 2

[0036] Example 2 Preparation of Yiqi Shengxian Pills

[0037] The Yiqi Shengxian Pill of Example 2 is prepared from the following raw materials:

[0038] There were 597 parts of Astragalus, 324 parts of Anemarrhena, 187 parts of Platycodon, 128 parts of Bupleurum and 141 parts of Cimicifuga.

[0039] Preparation:

[0040] (1) Take Astragalus, Anemarrhena, Platycodon grandiflorum, Bupleurum and Cimicifuga, wash, dry, crush into coarse powder, and set aside;

[0041] (2) Pour carbon dioxide into the above coarse powder, pressurize to 50MP under normal temperature conditions, expand for 8 minutes, release the pressure instantly, and obtain material A;

[0042] (3) Mix the above-mentioned material A with the mixed solvent, add an appropriate amount of zinc sulfate, the addition amount of zinc sulfate is 0.2% (w / w) of the weight of material A, and expose it to the high-pressure pulse electromagnetic field for 10 minutes under normal temperature conditions. Chinese medicine extract; wherein, ...

Embodiment 3

[0045] Example 3 Preparation of Yiqi Shengxian Pills

[0046] The Yiqi Shengxian Pill of Example 3 is prepared from the following raw materials:

[0047] There were 497 parts of Astragalus, 224 parts of Anemarrhena, 87 parts of Platycodon grandiflorum, 87 parts of Bupleurum and 41 parts of Cimicifuga.

[0048] For the preparation method, refer to Example 1.

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Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a qi-invigorating and collapse-ascending pill and a preparation method thereof. The qi-invigorating and collapse-ascending pill is prepared from the following raw materials in parts by weight: 200-800 parts of milkvetch roots, 100-500 parts of common anemarrhena rhizome, 50-300 parts of platycodon roots, 50-300 parts of Chinese thorowax roots and 20-200 parts of largetrifoliolious bugbane rhizome. The qi-invigorating and collapse-ascending pill provided by the invention is prepared by aspecific process, has high content of effective components, can obviously improve the influence of the heart function of a chronic congestive heart failure rat, improves the ejection fraction of the left ventricle and the short-axis contraction rate of the left ventricle, has low content of tannic acid and aflatoxin, and has high medication safety.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a Yiqi Shengxian pill and a preparation method thereof. Background technique [0002] Shengxian Decoction is a traditional Chinese medicine prescription. It is derived from Zhang Xichun's "Medical Blood Zhong Shen Xi Lu". It consists of 5 Chinese medicines, namely Astragalus, Anemarrhena, Platycodon grandiflorum, Bupleurum and Cimicifuga. Used for qi deficiency and blood stasis, yin and blood stasis do not follow the meridian, modern used to treat chronic atrophic gastritis, visceral ptosis, gastric volvulus, viral myocarditis, diabetes, blood in the stool after cervical cancer radiotherapy, viral myocarditis, intractable chest pain , Diabetes diarrhea, functional uterine bleeding, menorrhagia, menorrhagia caused by uterine fibroids and endometriosis, ring rush, ring leakage, postpartum and post-abortion, endless lochia, hemorrhoid bleeding, hematuria...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K9/20A61P9/04
CPCA61K9/20A61K36/233A61K36/346A61K36/481A61K36/71A61K36/8964A61K2236/10A61K2236/333A61K2236/51A61K2300/00
Inventor 罗庆进陈吉祥李素琴张志玲
Owner GUANGDONG SANLAN PHARMA CO LTD
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