Preparation method for joint production of 3,3,3-trifluoro-1,2-propanediol and 4-trifluoromethylethylene carbonate

Abstract

The invention discloses a preparation method for the joint production of 3,3,3-trifluoro-1,2-propanediol and 4-trifluoromethylethylene carbonate, which comprises the following steps: in the presence of hydrogen halide solution and organic base , 3,3,3-trifluoropropylene oxide reacts with carbon dioxide, the reaction temperature is 70°C-180°C, the reaction pressure is 0.1MPa-5MPa, and the reaction is completed to obtain 3,3,3-trifluoro-1,2-propanediol and 4-trifluoromethyl ethylene carbonate crude product, through separation, refining to obtain the target product 3,3,3-trifluoro-1,2-propanediol and 4-trifluoromethyl ethylene carbonate, wherein the hydrogen halide consumption is 0.5%-20% of the molar weight of 3,3,3-trifluoropropylene oxide, and the amount of organic base is 0.5%-20% of the molar weight of 3,3,3-trifluoropropylene oxide. The invention has the characteristics of mild reaction conditions, simple operation, good reaction atom economy, and adjustable product distribution, and is mainly used for the joint production of 3,3,3-trifluoro-1,2-propanediol and 4-trifluoromethyl vinyl carbonate.

Description

technical field [0001] The invention relates to a preparation method of fluorine-containing alcohol and fluorine-containing five-membered cyclic carbonate, in particular to a method for co-production of 3,3,3-trifluoro-1,2-propanediol (TFPG) and 4-trifluoromethane The preparation method of ethylene carbonate (TFPC). Background technique [0002] The introduction of trifluoromethyl into organic compounds can significantly change the acidity, dipole moment, polarity, lipophilicity, and chemical and metabolic stability of the compound. Compounds containing trifluoromethyl are widely used in defense industry, high-tech industry and life increasingly important role in science. 3,3,3-Trifluoro-1,2-propanediol (TFPG), as a kind of fluorine-containing alcohol, contains a trifluoromethyl group and two hydroxyl groups in its structure. It has a unique structure, excellent performance, and broad application prospects; 3, 3,3-Trifluoropropene carbonate (TFPC) is an important trifluoro...

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Problems solved by technology

This method is carried out intermittently in a high-pressure reactor, the reaction efficiency is low, and there is a risk of metal tungsten residue in the product, which does not meet the high-quality requirements of battery-grade reagents

[0010] Although some reports about TFPG or TFPC have been published, there are no public reports about the co-production of TFPG and TFPC. More importantly, there are various degrees of existence in these methods such as harsh reaction conditions, poor safety performance; reaction atom economy. Poor performance, low yield; many reaction steps, complex reaction system; highly toxic and harmful substances involved, unfriendly to the environment; metal residues, low product quality and other deficiencies, Cheng needs to develop a mild reaction condition, easy operation, atom economy Preparation method for co-production of 3,3,3-trifluoro-1,2-propanediol and 4-trifluoromethylethylene carbonate with good product distribution

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