Global human mtDNA development tree classified query method based on integrated learning

A query method and integrated learning technology, applied in the field of global human mtDNA developmental tree classification query, can solve problems such as difficult to meet actual needs, insufficient practicability, and low accuracy rate

Active Publication Date: 2018-05-18
YUNNAN UNIV
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Problems solved by technology

[0005] As far as the current global human mtDNA development tree classification query method is concerned, due to the problem of algorithm d

Method used

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  • Global human mtDNA development tree classified query method based on integrated learning
  • Global human mtDNA development tree classified query method based on integrated learning
  • Global human mtDNA development tree classified query method based on integrated learning

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Embodiment

[0030] figure 1 It is a specific implementation flow chart of the global human mtDNA developmental tree classification query method based on integrated learning in the present invention. Such as figure 1 As shown, the global human mtDNA developmental tree classification query method of the present invention, its specific steps are as follows.

[0031] S101: Obtain training data:

[0032] First, a number of mtDNA data are manually measured. Each piece of data contains the mtDNA variation site sequence and the corresponding most likely classification. Each variation site sequence contains the specific information of several variation sites, and then obtains the global human mtDNA development Tree data, including all classifications and the sequence of mtDNA variation sites corresponding to each classification.

[0033] The mtDNA data used in this example is selected from the real mtDNA raw data in various human regions provided by the Southwest Biodiversity Laboratory of the ...

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Abstract

The invention discloses a global human mtDNA development tree classified query method based on integrated learning. Artificially-measured mtDNA data is adopted to train a neural network classifier, mtDNA development tree data is adopted to calculate parameters of a naive Bayes classifier, mutation loci of mtDNA to be classified and queried are input into the neural network classifier to obtain thefirst Q possible classifications, merging the mutation loci of mtDNA to be classified and queried and mutation locus sequences corresponding to the first Q possible classifications to obtain input mutation locus sequences of the naive Bayes classifier, calculating to obtain the weights of various mutation loci of the input mutation locus sequences, obtaining first Q possible classification through the naive Bayes classifier, and weighting probabilities of the two groups of mutation locus sequences to obtain the first Q possible classifications as the final classification result. By means of the global human mtDNA development tree classified query method based on integrated learning, the advantages of the neural network classifier and the naive Bayes classifier are comprehensively utilized, and the accuracy of global human mtDNA development tree classified query is improved.

Description

technical field [0001] The invention belongs to the technical field of machine learning, and more specifically relates to a global human mtDNA development tree classification query method based on integrated learning. Background technique [0002] my country is a country with a large population. Based on such a large country base, and the continuous exchanges and integration of various regions in the long river of history, as well as the isolation and migration based on geographical relations, my country's multi-ethnic population characteristics have gradually formed, providing researchers with A rich and diverse genetic treasure trove. But how to use such a treasure trove of genes to study human origin, migration, development and genetic structure is a problem we face. The research on the origin, migration and evolution of various ethnic groups is not only a major scientific issue, but also involves the self-identification of each ethnic group, which has important humanisti...

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Application Information

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IPC IPC(8): G06F19/18G06F19/22G06F17/30G06K9/62
CPCG06F16/285G16B20/00G16B30/00G06F18/24155
Inventor 周维彭旻晟贾俊燕王文智向文坤张亚平
Owner YUNNAN UNIV
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