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A pharmaceutical composition for preventing and treating neurodegenerative diseases, its preparation method and application

A neurodegenerative and compositional technology, which is applied in drug combinations, nervous system diseases, and pharmaceutical formulations, and can solve problems such as cumbersome preparation processes and complex prescriptions

Active Publication Date: 2021-03-02
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still problems such as relatively complicated prescription and cumbersome preparation process.

Method used

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  • A pharmaceutical composition for preventing and treating neurodegenerative diseases, its preparation method and application
  • A pharmaceutical composition for preventing and treating neurodegenerative diseases, its preparation method and application
  • A pharmaceutical composition for preventing and treating neurodegenerative diseases, its preparation method and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0027] 1. Prescription: Ginseng 30g, Angelica 50g, Yizhiren 10g

[0028] 2. Preparation method: take each raw material of the prescription amount, add auxiliary materials starch granulation, magnesium stearate, dextrin, microcrystalline cellulose, evenly prepare granules, compress into tablets, and obtain tablets.

Embodiment 2

[0029] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0030] 1. Prescription: Ginseng 10g, Angelica 50g, Yizhiren 30g

[0031] 2. Preparation method: take each raw material of the prescription amount, add auxiliary materials starch granulation, magnesium stearate, dextrin, microcrystalline cellulose, evenly prepare granules, compress into tablets, and obtain tablets.

Embodiment 3

[0032] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0033] 1. Prescription: Ginseng 10g, Angelica 30g, Yizhiren 50g

[0034] 2. Preparation method: take each raw material of the prescription amount, add auxiliary materials starch granulation, magnesium stearate, dextrin, microcrystalline cellulose, evenly prepare granules, compress into tablets, and obtain tablets.

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly provides a pharmaceutical composition for preventing and treating neurodegenerative diseases. The pharmaceutical composition comprises the following raw material medicines by weight: 1 to 30 parts of ginseng, 1 to 50 parts of Chinese angelica and 1 to 50 parts of fructus alpiniae oxyphyllae. The invention also provides a preparation method and specific use of the pharmaceutical composition. Pharmacological experiments prove that based on relevant objective indexes of experimental groups on a rat dementia model, a vascular rat dementia model, a rat cerebral pial microcirculation model and other model, the pharmaceutical composition has a good treatment effect on degenerative diseases of central nervous system.

Description

technical field [0001] The invention relates to a pharmaceutical composition for preventing and treating neurodegenerative diseases and its preparation method and application, in particular to a pharmaceutical composition for treating and alleviating senile dementia, vascular dementia or mild cognitive impairment and its preparation method. The preparation method and application belong to the technical field of traditional Chinese medicine. Background technique [0002] Vascular dementia (VD) is a chronic, acquired, and progressive cognitive impairment syndrome caused by different types of cerebrovascular damage. The main symptoms are learning and memory impairment, which may be accompanied by motor, language, etc. , visuospatial and personality disorders. According to the epidemiological survey, the incidence rate of dementia in the elderly over 65 years old in my country is 3.9%, of which VD accounts for 68.5%. With the aging of the world's population, the incidence of V...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61P25/28
CPCA61K36/232A61K36/258A61K36/725A61K36/9062A61K2300/00
Inventor 文跃强沈涛徐世军贾波李斌魏江平付颖
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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