Preparation method of traditional Chinese medicine compound extract, extract and antibacterial composition

Abstract

The invention discloses an antibacterial composition of a traditional Chinese medicine compound extract, the extract and application to an antibacterial composition. The antibacterial composition comprises the following steps: (1), mixing the following components in parts by weight: 5 to 15 parts of radix glycyrrhizae, 15 to 25 parts of scutellariae radix veta, 5 to 15 parts of radix et rhizoma rhei, 15 to 25 parts of cortex phellodendri, and 15 to 25 parts of radix sophorae flavescentis, and crushing the mixture; (2), adding distilled water for soaking, adding 1500 to 2500 U/g enzyme for hydrolysis, stirring for 1 to 2h in 35 to 50 DEG C water bath, filtering, and concentrating and drying filtrate, so as to obtain the traditional Chinese medicine compound extract; the enzyme is selected one or more of cellulase, pectinase or protease. The formed traditional Chinese medicine compound extract in the antibacterial composition can be applied to emulsifiable paste, gel and suspension, is good in antibacterial effect and mild, and does not have toxic or side effects.

Description

technical field [0001] The invention relates to a preparation method of an extract and a composition prepared from the extract, in particular to a preparation method of a compound Chinese medicine extract and an antibacterial composition containing the extract. Background technique [0002] Some dosage forms are easily contaminated by common microorganisms such as Escherichia coli, Staphylococcus aureus, and Candida albicans in the process of production and use, resulting in corruption, so it is often necessary to add bacteriostatic agents. At present, the most commonly used antibacterial agents such as DMDM ​​hydantoin, methylparaben, propylparaben, and Kethon are obtained through chemical synthesis. These antibacterial agents have potential risks, have certain chronic toxicity to the skin, and may cause cancer or sensitization. Therefore, research and development of natural antibacterial ingredient formulas that have an inhibitory effect on Escherichia coli and other micr...

AI Technical Summary

Problems solved by technology

[0009] In the prior art, the patent "A Bacteriostatic Gel" with the application number 201610467423.6 is formulated with chlorhexidine acetate antibacterial ingredients. Although the antibacterial effect is strong, it has low toxicity and is harmful to the eyes, respiratory system and skin. certain irritation

Patent Application No. 201310165844.7 "A Hand Sanitizer Containing Various Natural Antibacterial Ingredients and Its Manufacturing Process", the antibacterial ingredients described are grape seeds, pomegranate seeds, pomegranate peel, privet tree fruit, camphor tree fruit , Cinnamomum camphora leaf extract, but the extraction method is complex and the antibacterial effect of the product is unknown