Toothpaste for relieving pain, protecting gingiva and preventing gingival bleeding and preparation method thereof

A technology for bleeding gums and toothpaste, which is applied in the field of toothpaste for relieving pain, protecting gums and preventing gum bleeding and its preparation, can solve problems such as inability to increase effective concentration, difficult drug effect, and effective drugs with odor, etc., to overcome drug resistance Medicinal properties, obvious public health value, and the effect of preventing bleeding gum disease

Inactive Publication Date: 2018-07-31
昆药集团健康产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, medicated toothpaste also has its disadvantages. First, the toothpaste cannot be kept in the mouth for too long, that is, it will be rinsed out, making it difficult for the drug to exert its medicinal effect in a short time, and the dosage of the special drug must also avoid stimulating the soft tissues in the mouth, so it cannot be increased to Sufficient effective concentration, the effect of toothpaste itself, is often blocked by the dirt in the mouth or limited by morphological characteristics, so

Method used

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  • Toothpaste for relieving pain, protecting gingiva and preventing gingival bleeding and preparation method thereof
  • Toothpaste for relieving pain, protecting gingiva and preventing gingival bleeding and preparation method thereof
  • Toothpaste for relieving pain, protecting gingiva and preventing gingival bleeding and preparation method thereof

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preparation example Construction

[0021] The preparation method of the toothpaste for relieving pain, protecting gums and preventing bleeding gums of the present invention comprises the following steps:

[0022] A. Ingredients: First, mix and dissolve saccharin, sodium benzoate, sodium pyrophosphate and deionized water completely, then pour them into a water premix tank, and at the same time pour sorbitol and the rest of deionized water to obtain material a, pour PEG400 and glycerin Put it into the glycerin tank, start stirring, pour in CMC, guar gum and carrageenan, stir for 2-3 minutes to obtain material b, pour the active substance of Yunnan Hongyao Powder, titanium dioxide, silicon dioxide, calcium hydrogen phosphate and K12 in sequence The material c is obtained from the powder hopper for use;

[0023] B. Paste making: Add material a and material b to the paste making machine with the vacuum pump turned on in turn, turn on the colloid mill and stir for 10~15 minutes, turn off the colloid mill and vacuum p...

Embodiment 1

[0036] calcium carbonate toothpaste

[0037] Formula: calcium carbonate 40.0, sorbitol 22.0, CMC-Na 1.1. Sodium lauryl sulfate 1.8, active ingredient of Yunnan Hongyao Powder 0.2, sodium saccharin 0.2, methyl paraben 0.05, essence 1.1, and the balance of deionized water, all of which are percentages by weight.

[0038] Production method: first add sorbitol to the vacuum paste making machine, then add CMC-Na and mix well, then add most of the deionized water, mix again, in the state of vacuum stirring, add in turn with a small part of deionized water Dispersed and dissolved sodium saccharin, active ingredients of Yunnan Hongyao Powder, nigerium methyl ester solution, calcium carbonate, sodium lauryl sulfate, and stirred at high speed in a vacuum state to fully mix, and finally added essence, and again in a vacuum state Under high-speed stirring, fully emulsified and mixed to obtain calcium carbonate toothpaste.

Embodiment 2

[0040] Dibasic calcium phosphate toothpaste

[0041] Formula: calcium hydrogen phosphate 45.0, glycerin 10.0, sorbitol 25.0, sodium carboxymethylcellulose 1.2, sodium pyrophosphate 0.5, active ingredient of Yunnan Hongyao powder 0.8, K12 2.0, sodium saccharin 0.2, sodium benzoate 0.15, spearmint essence 1.2, The balance of deionized water, the above are weight percentages

[0042] Production method: Evenly disperse sodium carboxymethyl cellulose with glycerin, inhale it into a vacuum paste making machine, then add sorbitol and part of deionized water to make the adhesive swell and peptize, and take part of deionized water to dissolve sodium pyrophosphate , after the active ingredients of Yunnan Hongyao powder, sodium saccharin, and sodium benzoate are dissolved, they are also sucked into the vacuum paste pot and mixed well. Add calcium hydrogen phosphate and K12 respectively, and allow to degas and mix evenly under vacuum to obtain calcium hydrogen phosphate toothpaste.

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Abstract

The invention discloses a toothpaste for relieving pain, protecting gingiva and preventing gingival bleeding and a preparation method thereof. The toothpaste for relieving pain, protecting gingiva andpreventing gingival bleeding comprises an effective amount of active substances of Yunnan Hongyao San and auxiliary materials, wherein the active substances of Yunnan Hongyao San are prepared from the following raw materials in parts by weight: 80-120 parts of radix notoginseng, 200-300 parts of rhizoma paridis, 40-60 parts of radix dactylicapni scandentis, 80-120 parts of radix ampelopsis delavayanae, 90-100 parts of cortex pseudostreblus indica, 70-80 parts of radix seu folium dolichoris falcati, 40-60 parts of radix psammosilenes tunicoidis, 20-40 parts of rhizoma acori tatarinowii, 80-120 parts of radix scutellariae hyericifoliae and 100-200 parts of aconitum vilmorinianum praeparata; the preparation method comprises steps of material preparation, paste preparation and post-processing. The toothpaste provided by the invention has medicinal effects of relieving pain, stopping bleeding and protecting gingiva, also has effects of promoting gingival growth to prevent various gingivalbleeding diseases, and has advantages of low cost, good effect, wide appropriate crowds, high safety, no toxicity, strong pharmacological action, basically no drug dependence, and significant publichealth value.

Description

technical field [0001] The invention belongs to the technical field of daily necessities, and in particular relates to a toothpaste for relieving pain, protecting gums and preventing bleeding of gums and a preparation method thereof. Background technique [0002] Toothpaste is a necessity of life. There are a wide variety of toothpastes on the market now, and a considerable part of them are fluoride toothpaste. However, experts point out that children under the age of 6 use fluoride toothpaste. There is a greater risk, because fluorine is a toxic substance. It will cause thin teeth and reduce the hardness of bones. Fluorine has been identified by the World Health Organization as a potentially toxic trace element, ranking first with lead and mercury trace elements. More than 20 provinces and cities in China belong to high-fluoride areas, and the use of fluoride toothpaste in these areas will undoubtedly make the situation worse. Toothpaste is a complex mixture. It usually ...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61Q11/00A61K36/896A61P1/02A61P7/04A61P29/00
CPCA61K8/9789A61K8/9794A61K36/258A61K36/36A61K36/48A61K36/539A61K36/60A61K36/66A61K36/714A61K36/87A61K36/888A61K36/896A61P1/02A61P7/04A61P29/00A61Q11/00A61K2300/00
Inventor 万江波罗声
Owner 昆药集团健康产业有限公司
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