Sectionable cassette and embedding frame with tissue immobilizing separable lid, and methods for preparing biopsy tissue samples

A tissue sample and cover technology, applied in chemical instruments and methods, test sample preparation, sampling, etc., can solve the problems of increasing the cost of pathological procedures

Pending Publication Date: 2018-07-31
BIOPATH AUTOMATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Each cassette is essentially consumed by the slicer procedure, which increases the cost of the pathology procedure
Furthermore, since sliceable FEP / PFA materials are not rigid, it is challenging to fabricate reliable covers from this material that do not deform dimensionally during shipping and storage.

Method used

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  • Sectionable cassette and embedding frame with tissue immobilizing separable lid, and methods for preparing biopsy tissue samples
  • Sectionable cassette and embedding frame with tissue immobilizing separable lid, and methods for preparing biopsy tissue samples
  • Sectionable cassette and embedding frame with tissue immobilizing separable lid, and methods for preparing biopsy tissue samples

Examples

Experimental program
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Effect test

Embodiment Construction

[0062] first reference figure 1 and 2 , shows an assembly 10 constructed in accordance with an illustrative embodiment of the invention. Assembly 10 includes a tissue sample cassette 12 carried within a frame 14 that includes a peripheral portion 16 . A cover 18 is detachably coupled to the peripheral portion 16 . The peripheral portion 16 generally includes an interior defined between surrounding walls 16a, 16b, 16c, 16d, and a cover 18 is sized and configured to fit within and detachably couple to at least one of the surrounding walls 16a, 16b, 16c, 16d. one up. Frame 14 generally includes an interior defined between surrounding outer walls 14a, 14b, 14c, 14d, and also as generally discussed in the patents and patent applications incorporated above and for the same purpose, box 12 is sized and configured to frictionally or "snap" fit within the interior and move within the interior between at least a first position and a second position. first position in Figure 3B sh...

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PUM

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Abstract

A histologic tissue sample support device (200) includes a tissue cassette (112), a frame (14), and a lid (118"). The tissue cassette (112) has a recess (112b) including a body (112a) with at least one side wall and a bottom wall (112c) and is formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. The tissue cassette (112) is movably coupled to the frame (14). The lid (118") is separably coupled to a peripheral portion (16) of the frame (14). When the lid (118") is separated from the peripheral portion (16), the lid (118") and the tissue cassette (112) are capable of moving from a first position to a second position with respect to the frame (14), and in the second position thebottom wall (112c) and at least a portion of the side wall extend beyond a bottom edge of the frame (14) for sectioning in the microtome.

Description

technical field [0001] The present invention relates generally to supports for processing and embedding tissue samples for pathological analysis, and more particularly to microtome sliceable supports and supports having tissue-secured detachable covers that can accommodate one or more tissue samples frame. Background technique [0002] To accurately diagnose various tissue diseases and conditions, medical professionals must remove one or more tissue samples from a patient's body. This process of taking tissue from the body is called a biopsy. Once one or more tissue samples are removed and sent to a pathology laboratory, the tissue undergoes a series of procedures performed by a histopathologist and eventually a pathologist in order to diagnose one or more conditions associated with the tissue. The present invention relates generally to those procedures typically performed by a histotechnologist to prepare one or more tissue samples into slides that can be analyzed by a pa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/31B01L3/00G01N1/00G01N1/28
CPCG01N1/06G01N2001/315B01L3/50825G01N1/36B01L2200/025B01L2300/042B01L2300/043B01L2300/0609B01L2300/069G01N2001/366G01N1/312
Inventor W·P·威廉森四世
Owner BIOPATH AUTOMATION
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