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Injection device

A technology of injection port and liquid, which is applied in the direction of syringe, hypodermic injection device, injector by jet action, etc.

Pending Publication Date: 2018-08-21
DAICEL CHEM IND LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the other hand, since there is no such mechanical structure, it cannot be said that it is always easy to inject the drug solution to the desired part in the target area.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Here, based on Figure 6 and Figure 7 , the experimental results regarding the vibration in the target area when the injection device 1 according to the present invention is used will be described. In this vibration experiment, the injection liquid was injected in a state where the injection port 31a of the injection device 1 was arranged directly above the polyacrylamide gel imitating the target area. The vertical vibration of the polyacrylamide gel at this time (vibration along the ejection direction of the ejected liquid) was imaged with a camera, and image processing was performed to visualize the displacement caused by the vibration.

[0085] Depend on Figure 6 The line L11 of , represents the pressure transition (injection pressure transition) of the injected injection liquid when the injection device 1 injects the injection liquid. This pressure shifts due to the Figure 4 The indicated pressure transitions are the same, so a detailed description thereof wi...

Embodiment 2

[0091] The experimental conditions and experimental results are shown below for the intradermal injection experiment of rabbit living body performed by the injection device 1 of the present invention and the needle-equipped syringe of the comparative example. In addition, the following experimental conditions are used to confirm the inflammatory reaction (erythema and scab) at each elapsed time (24 hours, 48 ​​hours, 72 hours) when inflammatory substances are injected into the skin tissue of the rabbit organism. The formation of the skin, the formation of edema) is the purpose. In addition, the injection of the injection liquid with the needle syringe is performed at a certain pressurization speed.

[0092]

[0093] (About the shot object)

[0094] Std used: JW / CSK male 16-week-old shorn-smooth-skinned rabbits confirmed.

[0095] (About ejaculation fluid and injection fluid)

[0096] Aqueous solutions of the following inflammatory substances were used as injection liquids...

Embodiment 3

[0117] The experimental conditions and experimental results are shown below for the injection experiment of pig abdominal skin tissue performed by the injection device 1 of the present invention, the needle-equipped syringe of the comparative example, and the spring-driven injector (needle-free injector). In addition, the following experimental conditions are aimed at injecting an MRI contrast agent into the abdominal skin tissue of pigs, and confirming the penetration of the MRI contrast agent into the abdominal skin tissue of pigs using the images captured by the MRI apparatus.

[0118]

[0119] (About injection unit 1)

[0120] Flow velocity: 202m / s (equivalent to about 40MPa injection pressure)

[0121] Nozzle diameter: φ0.17mm

[0122] (About the syringe with a needle of the comparative example)

[0123] The injection of the injection solution with the needle syringe is performed at a certain pressurized speed.

[0124] Injection needle: 27G

[0125] (About the spri...

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PUM

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Abstract

An injection device for injecting an injection liquid containing a prescribed substance into a target region, the injection device being equipped with a storage unit for storing the injection liquid,a drive unit for imparting injection energy, a pressurization unit for pressurizing the injection liquid stored in the storage unit by using the injection energy from the drive unit, and an injectionunit for injecting the injection liquid that has been pressurized by the pressurization into the target region through an injection port. In addition, during the pressure transition of the injection liquid at the injection port, a convergent state of vibrations is achieved during the pressure transition within a prescribed interval from starting to build pressure, and initial first vibration element pressure during the vibrations within the prescribed interval reaches a peak value thereof at a prescribed speed, or the vibrations within the prescribed interval are of a frequency that belongs toa prescribed frequency range. As a result, it is possible to reduce invasiveness for the target region when performing an injection.

Description

technical field [0001] The present invention relates to an injection device that injects an injection liquid containing a predetermined substance to a target area, and particularly relates to a technique for injecting an injection liquid to a target area for treatment by imparting high-speed energy to the injection liquid. Background technique [0002] Syringes are exemplified as devices for administering medicinal solutions to target areas such as living bodies. In recent years, needle-free syringes without injection needles have been developed for ease of handling and hygiene. In general, in needle-free injectors, a structure in which a liquid medicine pressurized by a driving source such as a compressed gas or a spring is ejected toward a target area, and the kinetic energy of the liquid medicine is used to inject the liquid medicine into the target area has been put into practical use; , as the other driving source, the utilization of gunpowder combustion was studied. I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/303
CPCA61M5/484G16H40/63G16H20/17A61M5/30A61M5/42A61M5/482A61M5/2422
Inventor 小田慎吾永松信二山下邦彦桥本文
Owner DAICEL CHEM IND LTD