Potassium aspartate compound electrolyte injection and preparation method thereof

A technology of potassium aspartate and compound electrolyte, which is applied in the field of compound potassium aspartate sodium lactate electrolyte injection and preparation thereof

Inactive Publication Date: 2018-08-28
LIAONING YAOLIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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[0004] The present invention ai...

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  • Potassium aspartate compound electrolyte injection and preparation method thereof
  • Potassium aspartate compound electrolyte injection and preparation method thereof
  • Potassium aspartate compound electrolyte injection and preparation method thereof

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[0038] Preparation method: put sodium chloride, glucose, and sodium lactate 40% solution in a beaker according to a predetermined ratio, add 240mL of water for injection at 70°C, stir to dissolve; cool, check the pH, and adjust the pH to 5.6-6.0 with hydrochloric acid; To 300mL, add activated carbon, filter through a 0.22um membrane to obtain injection 1; dissolve a predetermined proportion of potassium aspartate in 200mL water for injection, add activated carbon, and filter through a 0.22um membrane to obtain injection 2; Liquid 1 and injection 2 were filled into the first and second chambers of the double-chamber bag respectively; sterilized at 121°C for 15 minutes.

[0039] The content of each component of the injection is shown in Table 1, calculated in 500 mL.

[0040] Table 1

[0041]

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Abstract

The invention provides potassium aspartate compound electrolyte injection and a preparation method thereof. 500mL of the injection is prepared from the following ingredients by weight: 0.25 to 0.75g of sodium chloride, 15 to 20g of glucose, 1 to 2g of 40% sodium lactate solution, 0.6 to 1.0g of potassium aspartate and the balance of water. A product of the potassium aspartate compound electrolyteinjection is total parenteral nutrition injection, can provide varieties of electrolyte and saccharides for the human body at the same time and can achieve the purpose of replenishing body fluid, maintaining water and electrolyte balance and providing energy.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound potassium aspartate sodium lactate electrolyte injection and a preparation method thereof. Background technique [0002] Disorders of water and electrolyte metabolism are very common in clinical practice. Diseases of many organ systems, some systemic pathological processes, such as liver cirrhosis, diabetes, pulmonary heart disease, burns and post-operation, etc., can cause or be accompanied by water and electrolyte metabolism disorders; some changes in the external environment, some Iatrogenic factors such as improper use of drugs often lead to water and electrolyte metabolism disorders. If it is not corrected in time, the disturbance of water and electrolyte metabolism itself can cause corresponding obstacles to the physiological functions of various organ systems in the whole body, especially the cardiovascular system and nervous system, and the substa...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K31/7004A61K31/19A61K31/198A61K9/08A61P3/12
CPCA61K33/14A61K9/0019A61K9/08A61K31/19A61K31/198A61K31/7004A61K2300/00
Inventor 于航毕洪书陶闰红
Owner LIAONING YAOLIAN PHARMA
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