Preparation of Tumor Cell Apoptotic Body Vaccine with Nutrient Deficiency and Its Antitumor Application
A tumor cell apoptosis and apoptotic body technology, which is applied to tumor cell apoptotic body, nutrient deficiency to prepare tumor cell apoptotic body vaccine and its anti-tumor application field, can solve the problem of low tumor inhibition rate in mice, The immune effect is not strong, adverse reactions and other problems, to achieve the effect of killing and removing tumor cells, enhancing the effect of radiotherapy and chemotherapy, and prolonging the survival time
Active Publication Date: 2022-02-11
庆云堂生物科技(北京)有限公司
View PDF2 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
These traditional cancer treatment methods have certain limitations due to their poor targeting and strong toxicity. While killing tumor cells, they will also damage normal cells and cause adverse reactions.
[0003] Tumor vaccines are one of the current research hotspots. Some studies use physical methods to inactivate cells to prepare whole-cell vaccines, but this method has weak immune effects, poor targeting and low tumor inhibition rate in mice.
[0004] Through the search, there is no report on the use of tumor cell apoptotic bodies in anti-tumor vaccines
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0023] The present invention will be further described in detail below in conjunction with the accompanying drawings and through specific embodiments. The following embodiments are only descriptive, not restrictive, and cannot limit the protection scope of the present invention.
[0024] In this experiment, taking HepG2 liver cancer cells as an example, the specific implementation methods are described in detail, as follows:
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The present invention relates to a vaccine for preparing tumor cell apoptotic body due to lack of nutrition and its anti-tumor application. As an immunogen for the preparation of antitumor vaccines. The anti-tumor vaccine-"apoptotic body vaccine" produced by the present invention is used as a means of biological immunotherapy or tumor prevention. It has stronger targeting and fewer side effects when it works. It can be activated or Strengthen the body's own anti-tumor immunity to achieve the purpose of killing and eliminating tumor cells. At the same time, this "apoptotic body vaccine" has a broad spectrum in activating the body's immune cells to fight tumors.
Description
technical field [0001] The invention belongs to the field of anti-tumor vaccines, and relates to tumor cell apoptotic bodies, in particular to a tumor cell apoptotic body vaccine prepared from nutritional deficiency and its anti-tumor application. Background technique [0002] At present, the treatment methods for cancer mainly include surgery, radiation therapy and drug therapy. These traditional cancer treatment methods have certain limitations due to their poor targeting and strong toxicity, which can damage normal cells while killing tumor cells and cause adverse reactions. [0003] Tumor vaccines are one of the current research hotspots. Some studies have used physical methods to inactivate cells to prepare whole-cell vaccines. However, this method has weak immune effects, poor targeting and low tumor inhibition rate in mice. [0004] Through searching, there is no report on the use of tumor cell apoptotic bodies in anti-tumor vaccines. Contents of the invention [...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Patents(China)
IPC IPC(8): A61K39/00A61P35/00A61P37/04C12N5/09
CPCA61K39/00A61P35/00A61P37/04C12N5/0693
Inventor 刘安军王喜玲
Owner 庆云堂生物科技(北京)有限公司