Dose-distribution estimation in proton therapy

A proton, dose technology used in the field of radiation therapy to solve problems such as the inability to accurately predict the results achieved by proton beam therapy

Active Publication Date: 2018-12-21
VARIAN MEDICAL SYST INT AG
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  • Summary
  • Abstract
  • Description
  • Claims
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Problems solved by technology

As a result, existing methods of treatment plan development, such as those based on typical photon depth-dose curves, cannot accurately predict the outcomes likely to be achieved with proton beam therapy.

Method used

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  • Dose-distribution estimation in proton therapy
  • Dose-distribution estimation in proton therapy
  • Dose-distribution estimation in proton therapy

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Embodiment Construction

[0015] figure 1 An embodiment of the invention is shown in , which illustrates an exemplary proton beam dose profile planning tool 10 employing proton beam geometric expected dose (GED) to develop and estimate a patient-specific proton therapy treatment plan. The proton beam dose profile planning tool 10 predicts the dose that a volume of interest, such as a target volume, will receive during a proton beam therapy session. The proton beam dose distribution planning tool 10 predicts a three-dimensional dose distribution for a new patient based on patient anatomy and proton field geometry.

[0016] The proton beam dose distribution planning tool 10 includes a patient geometry parameterization module 12 , a dose prediction module 14 , a knowledge assimilation module 16 and a knowledge base 18 . The patient geometry parameterization module 12 generates a set of parameters or metrics based on the individual patient anatomical geometry with respect to various factors affecting the ...

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Abstract

A system for estimating a dose from a proton therapy plan includes a memory that stores machine instructions and a processor coupled to the memory that executes the machine instructions to subdivide arepresentation of a volume of interest in a patient anatomy traversed by a planned proton field into a plurality of voxels. The processor further executes the machine instructions to determine the distance from the source of the planned proton beam to one of the voxels. The processor also executes the machine instructions to compute the discrete contribution at the voxel to an estimated dose received by the volume of interest from the planned proton beam based on the distance between the source and the volume of interest.

Description

technical field [0001] This description relates generally to radiation therapy, and more specifically to proton beam therapy treatment plan development. Background technique [0002] Radiation therapy treatment plan development typically employs medical imaging, such as X-rays, computed tomography (CT), magnetic resonance imaging (MRI), and the like. Typically, a series of two-dimensional patient images, each representing a two-dimensional cross-sectional "slice" of the patient's anatomy, is used to reconstruct a volume of interest (VOI) or a three-dimensional representation of the structure of interest from the patient's anatomy. [0003] Typically, a VOI includes one or more organs of interest, which typically include: a planning target volume (PTV), such as a malignant growth or an organ including malignant tissue targeted by radiation therapy; a malignant growth at risk of radiation therapy exposure A nearby relatively healthy organ at risk (OAR); or a larger portion of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/103A61N5/1071A61N5/1031A61N2005/1087A61N2005/1041
Inventor E·库塞拉M·I·科德罗·马克思J·诺德
Owner VARIAN MEDICAL SYST INT AG
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