Method for measuring glycated hemoglobin and device for measuring glycated hemoglobin
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- TOSOH CORP
- Publication Date
- 2020-10-09
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Abstract
Description
technical field
[0001] The present invention relates to a method and device for measuring glycated hemoglobin in a blood sample by liquid chromatography, and more particularly to a glycated hemoglobin capable of measuring glycated hemoglobin as a diagnostic index for diabetes in a blood sample group in which blood samples containing abnormal hemoglobin may be mixed measuring method and measuring device. Background technique
[0002] Hemoglobin has an α2β2 structure consisting of 2 α chains and 2 β chains. In addition to hemoglobin A, which accounts for about 97% of the total hemoglobin, it is composed of hemoglobin F and hemoglobin A2. The hemoglobin F has 2 α chains and 2 The α2γ2 structure composed of γ chains accounts for less than 1% of the total hemoglobin, and the hemoglobin A2 has an α2δ2 structure composed of two α chains and two δ chains and accounts for less than 1% of the total hemoglobin.
[0003] Hemoglobin non-enzymatically combines with sugar (blood sugar) pr...