Method for preparing emodin and physcion from cassia seeds

Abstract

The invention discloses a method for preparing emodin and physcion from cassia seeds, belonging to the field of functional component extraction. The method comprises the following steps: selecting dried leguminous cassia seeds for subsequent usage; weighing the dried cassia seeds, allowing a material-liquid ratio (g / mL) of the cassia seeds to 60-80% ethanol to be 1: (6-10), performing flash extraction under the condition of room temperature, a voltage of 60-140 V and a rotation speed of 3600 r / min for 60-120 s, then carrying out filtering with eight layers of gauze, repeatedly extracting residues three times, and finally combining obtained extracts; mixing a crude extract with a developing agent, carrying out vibrating and centrifugation, and removing residues while leaving liquid; clarifying, filtering and concentrating the obtained material by using a ceramic ultrafiltration membrane; and concentrating remaining aqueous-phase materials, adding the concentrated aqueous-phase materialsto excess ethanol for precipitation, and performing suction filtration to obtain emodin and physcion crystals. Compared with conventional processes, the method of the invention prevents heat-sensitive anthraquinone glycoside in Chinese rhubarb from thermal damage; and the flash extraction process is stable, rapid and highly-efficient, does not need heating, only takes 60 s in single extraction, and can save a great amount of energy and time when applied to industrial production.

Description

technical field [0001] The invention relates to the field of extraction of functional components, in particular to a method for preparing emodin and emodin methyl ether from cassia seeds. Background technique [0002] Semen Cassiae is the dry mature seed of the annual herbaceous plant Cassia officinalis or Cassia officinalis, also known as "Huantongzi". Semen Cassiae contains multiple vitamins and rich amino acids, fats, carbohydrates, etc. In recent years, its health care function has been paid more and more attention by people. Cassia seed has the functions of clearing liver-fire, dispelling rheumatism, benefiting kidney and improving eyesight, etc. Drinking cassia seed tea regularly can make blood pressure normal, defecate unobstructed, and prevent old eyes from blurring. Tobacco is an important economic crop in my country, but tobacco diseases, especially leaf diseases, are often prevalent and cause heavy losses. Emodin, the active ingredient in Semen Cassiae, is widel...

AI Technical Summary

Problems solved by technology

[0003] At present, there are several problems in the extraction and purification of emodin and emodin methyl ether: the extraction and purification yield of emodin and emodin methyl ether is very low; the use of a large amount of organic solvents (such as formic acid, ethyl formate, etc.) is easy to cause environmental pollution. Pollution and cost increase; the active ingredient is seriously affected by the extraction and purification process, and the increase in yield usually results in a loss of activity

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