A gene recombinant spider silk protein tooth inlay and its preparation method

A technology of spider silk protein and gene recombination, which is applied in the field of genetic recombination spider silk protein tooth inlay and its preparation, and can solve the problems of human body rejection, inflammation, incompatibility of tooth inlay, etc.

Active Publication Date: 2021-11-02
江西丝科生物科技有限公司
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  • Abstract
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Problems solved by technology

[0004] In view of the shortcomings of the prior art described above, the purpose of the present invention is to provide a genetically recombined spider silk protein tooth inlay and its preparation method, which is used to solve the problem that the tooth inlay in the prior art is not compatible with the human body and is easy to produce with the human body. Rejection, problems with inflammation

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  • A gene recombinant spider silk protein tooth inlay and its preparation method

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Embodiment Construction

[0033] Embodiments of the present invention are described below through specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific implementation modes, and various modifications or changes can be made to the details in this specification based on different viewpoints and applications without departing from the spirit of the present invention.

[0034] Please refer to attached picture. It should be noted that the diagrams provided in this embodiment are only schematically illustrating the basic idea of ​​the present invention, and only the components related to the present invention are shown in the diagrams rather than the number, shape and shape of the components in actual implementation. Dimensional drawing, the type, quantity and proportion of each component can be change...

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Abstract

The invention provides a gene recombined spider silk protein tooth inlay and a preparation method thereof, comprising preparation of a gene recombined spider silk protein solution, freeze-drying of the gene recombined spider silk protein solution, dissolving the gene recombined spider silk protein in hexafluoroisopropanol or Preparation and machining of genetically recombined spider silk protein rods in water. By controlling the preparation parameters of the recombinant spider silk protein solution, parameters such as drying and curing, and doping with solid phase reinforcement particles, the mechanical properties of the genetically recombinant spider silk protein tooth inlay can be controlled, and excellent properties matching the mechanical parameters of human bones and tooth occlusion can be obtained. Dental inlays, and the dental inlays obtained by the present invention are compatible with the human body and will not cause inflammation problems.

Description

technical field [0001] The invention relates to the technical field of biomedical materials, in particular to a gene recombined spider silk protein tooth inlay and a preparation method thereof. Background technique [0002] A dental inlay is a restoration that is embedded inside a tooth to restore the shape and function of a tooth defect. According to different inlay materials, it can be divided into alloy inlay, resin inlay and porcelain inlay. Alloy inlays are made of metal alloys, which have good ductility and mechanical properties, and are ideal restoration materials for making posterior inlays; resin inlays are made of composite resins, whose composition and polymerization method are better than those of conventional filling resins. It is more excellent, the material wears less on the teeth, and is easy to repair. It is a good aesthetic inlay material; there are three main processing methods for porcelain inlays: there are porcelain inlays made directly on refractory m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61C8/00
Inventor 陶虎
Owner 江西丝科生物科技有限公司
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