Biodegradable magnesium alloy blood vessel rack

A magnesium alloy blood vessel and biodegradation technology, applied in stents, medical science, prostheses, etc., can solve problems such as acute or chronic inflammatory reactions, uncertain plastic deformation points of polymers, and disordered growth of vascular endothelial cells. Achieving excellent mechanical properties, good biocompatibility, and grain refinement

Active Publication Date: 2007-01-03

LIAONING YINYI BIOTECH CO LTD

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AI-Extracted Technical Summary

Problems solved by technology

[0004] At present, the main materials used to make vascular stents at home and abroad are stainless steel, titanium-nickel alloy and cobalt-chromium alloy, but these permanent metal stents will have the following disadvantages during the long-term implantation process: The permanent implant remains on the inner wall of the blood vessel, and the physical stimulation of the tension that does not match the blood vessel becomes a one-way side effect foreign body. Long-term stimulation causes the growth disorder of vascul...

Abstract

The biodegradable magnesium alloy blood vessel rack consists of magnesium in 60-95 wt% and other metals, including RE, for the rest. Metal magnesium as the basic material has excellent tissue compatibility and blood compatibility, and the added other metal, including RE, elements raise and improve the comprehensive performance, especially mechanical strength, plasticity, degradability and biocompatibility. The magnesium alloy blood vessel rack has tensile strength of 200-300 MPa, elastic module of 10-50 GPa, elongation at break of 2-10%and degrading half life of 6-18 weeks. Most of the degraded metal ions are drained through renal tubules while small part being utilized by human body.

Application Domain

StentsSurgery +1

Technology Topic

Half-lifeRenal tubule +13

Examples

Experimental program(6)

Example Embodiment

[0020] Example 1:

[0021] A biodegradable magnesium alloy vascular stent, its weight percentage composition is: zinc 5%-8%; calcium 0.5-5%; zirconium 1%-3%; neodymium 1%-3%; niobium 0-3%, The rest is magnesium. Its physical and chemical properties, especially its degradability can be adjusted by adding other metal elements with good biocompatibility; especially its degradability can be adjusted by adding other rare earth elements with good biocompatibility ; Its biocompatibility can be adjusted by adding other metal elements with good biocompatibility and rare earth elements; its processability can be adjusted by adding other metal elements with good biocompatibility.

Example Embodiment

[0022] Example 2:

[0023] A biodegradable magnesium alloy vascular stent is composed of 7% by weight of zinc; 0.5% of calcium; 1% of zirconium; 1% of neodymium; and the rest is magnesium. After further processing the shaped material, the physical properties of the material are measured as follows: tensile strength is 220Mpa; elastic modulus is 20Gpa; elongation at break is 8%; in vitro degradation half-life is 8 weeks.

Example Embodiment

[0024] Example 3:

[0025] A biodegradable magnesium alloy vascular stent is composed of 5% zinc; 2% calcium; 3% zirconium; 3% neodymium; 3% niobium, and the rest is magnesium. After further processing the shaped material, the physical properties of the material are measured as follows: the tensile strength is 270Mpa; the elastic modulus is 35Gpa; the elongation at break is 5%; the in vitro degradation half-life is 12 weeks.

PUM

Property	Measurement	Unit
Tensile strength	220.0	mPa
Elastic modulus	20.0	GPa
Tensile strength	270.0	mPa

Description & Claims & Application Information

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Wide temperature, low power consumption and high direct current superposition characteristic manganese zinc ferrite material and preparation method thereof

ActiveCN108275994Agrain refinementhigh density

Owner:南通三佳磁业有限公司

Water-soluble quenching agent

InactiveCN107805689Agrain refinementImprove final performance

Owner:山东思科工业介质有限公司

Classification and recommendation of technical efficacy words

grain refinement

Biodegradable magnesium alloy blood vessel rack

AI-Extracted Technical Summary

Problems solved by technology

Abstract

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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