Hemopoietic paste with small dosage and good mouthfeel and preparing method and application thereof

A technology with good taste and small dosage, which can be applied to medical preparations containing active ingredients, blood diseases, ointment delivery, etc. It can solve problems such as unfavorable absorption and transformation of the human body, poor patient compliance, agglomeration and agglomeration of extracts, etc., to achieve Effect of improving bioavailability, promoting release and dissolution, and low extraction cost

Inactive Publication Date: 2019-05-17
饶健 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Shengxue ointment mainly has the following problems in the process of technological preparation and clinical use: 1. The taste of Polygonum multiflorum, Radix Paeoniae Alba, and Dog Ridge is bitter and astringent. Poor patient compliance will significantly reduce the curative effect; 2. During the decoction and extraction of Chinese medicinal materials, double the amount of water will be added, and the concentrated extract will agglomerate and agglomerate, with poor fluidity, which is not conducive to human absorption Transformation; 3. General oral ointment will add refined honey or refined sugar with high sugar content in order to taste. For some cancer patients, the sugar intake after radiotherapy and chemotherapy needs to be strictly controlled, so it is necessary to screen and experiment with excipients

Method used

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  • Hemopoietic paste with small dosage and good mouthfeel and preparing method and application thereof
  • Hemopoietic paste with small dosage and good mouthfeel and preparing method and application thereof

Examples

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Effect test

Embodiment 1

[0040] A low-dose Shengxue ointment with good taste in this embodiment comprises the following raw materials in parts by weight: 13 parts of Polygonum multiflorum, 16 parts of Ligustrum lucidum, 17 parts of mulberry, 16 parts of Eclipta chinensis, 14 parts of Radix Paeoniae Alba, 13 parts of Radix Astragali 12 parts of dog spine;

[0041] The preparation method of described Shengxue ointment comprises the following steps:

[0042] (1) Processing and cleaning: Mix Polygonum multiflorum and black bean juice according to the mass ratio of 10:1, steam Polygonum multiflorum until the inside and outside are tan, dry and crush into soybean size for later use; Ligustrum lucidum, mulberry, Astragalus, Peony peony and Eclipta chinensis are rinsed with water, dried for later use; dog spines are fried until crispy yellow, and there is no residual golden fluff on the edge of one side, and taken out for later use; wherein, the preparation method of black bean juice is the same as that of Ex...

Embodiment 2

[0052] A low-dose Shengxue ointment with good taste in this embodiment comprises the following raw materials in parts by weight: 15 parts of Polygonum multiflorum, 17 parts of Ligustrum lucidum, 16 parts of mulberry, 18 parts of Eclipta chinensis, 14 parts of Radix Paeoniae Alba, 13 parts of Radix Astragali 12 parts of dog spine;

[0053] The preparation method of described Shengxue ointment comprises the following steps:

[0054] (1) Processing and cleaning: Mix Polygonum multiflorum and black bean juice according to the mass ratio of 10:1, steam Polygonum multiflorum until the inside and outside are tan, dry and crush into soybean size for later use; Ligustrum lucidum, mulberry, Astragalus, Rinse peony and Eclipta chinensis with water, dry them for later use; stir-fry the dog spines until they are crispy yellow, and there is no residual golden fluff on one side of the edge, take them out for later use; the method for making black bean juice is to take 10kg of black beans and...

Embodiment 3

[0060] A low-dose Shengxue ointment with good taste in this embodiment comprises the following raw materials in parts by weight: 14 parts of Polygonum multiflorum, 18 parts of Ligustrum lucidum, 17 parts of mulberry, 16 parts of Eclipta chinensis, 14 parts of Radix Paeoniae Alba, 12 parts of Radix Astragali 14 pieces of dog spine;

[0061] The preparation method of described Shengxue ointment comprises the following steps:

[0062] (1) Processing and cleaning: Mix Polygonum multiflorum and black bean juice according to the mass ratio of 10:1, steam Polygonum multiflorum until the inside and outside are tan, dry and crush into soybean size for later use; Ligustrum lucidum, mulberry, Astragalus, Peony peony and Eclipta chinensis are rinsed with water, dried for later use; dog spines are fried until crispy yellow, and there is no residual golden fluff on the edge of one side, and taken out for later use; wherein, the preparation method of black bean juice is the same as that of E...

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Abstract

The invention discloses hemopoietic paste with small dosage and good mouthfeel and a preparing method and application thereof, and relates to the technical field of hemopoietic preparations. Accordingto the hemopoietic paste, on the basis of unchanging ingredients of an existing hemopoietic traditional Chinese medicine composition, seven traditional Chinese medicinal materials including radix polygonum multiflorum preparata, fructus ligustri lucidi, fructus mori, herba ecliptae, radix paeoniae alba, radix astragali and rhizoma cibotii are subjected to working procedures of processing and thorough washing, superfine grinding, secondary aqueous extract concentration, secondary ethanol percolation concentration and mixed oscillating to obtain the orally-taken decocted paste. The paste basically has no toxic or side effects on the premise of guaranteeing safety and stability, and is good in mouthfeel, uniform in quality, adjustable in dosage, and capable of achieving the functions of hematogenesis and blood replenishing, liver and kidney nourishing, wind dispelling and heat clearing after being taken orally, has the good effect of relieving leukopenia caused by chemoradiotherapy for malignant tumors, and significantly enhances the immunocompetence of patients.

Description

technical field [0001] The invention relates to the technical field of blood-boosting preparations, in particular to a small-dose blood-boosting ointment with good taste and its preparation method and application. Background technique [0002] Most of the existing tumor treatment methods use chemotherapy and radiotherapy. Chemotherapy and radiotherapy are a treatment method that uses chemical drugs or radiation to prevent the proliferation, invasion, and metastasis of cancer cells until the final killing of cancer cells. While killing cancer cells, it will inevitably damage a large number of normal human cells, especially bone marrow stem cells that proliferate vigorously, resulting in a decrease in the number of peripheral leukocytes and other whole blood cells in the patient, and a decrease in the ability of bone marrow to produce blood, further leading to deficiency of Qi and blood, and immunity. Decreased, the ability to resist viral infection decreased. [0003] In res...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K36/704A61P35/00A61P37/04A61P7/00A61K9/06A61K47/40
Inventor 饶健谈发金王志锋
Owner 饶健
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