Mouse fixing device for epilepsy research experiments

Abstract

The invention discloses a mouse fixing device for epilepsy research experiments, which comprises a fixing platform, a head fixing unit, a vertebrae fixing unit, a limb fixing unit and a bottom supporting unit, wherein the fixing platform is detachably arranged on the upper part of the bottom supporting unit. The device can be used conveniently; the device has better effect of fixing the mouse, canprevent the head of the mouse from being crushed, and can prevent the mouse from being killed due to the crushing of the head, thereby ensuring the smooth progress of the epilepsy research experiments, preventing the mouse from escaping, and preventing the mouse from greatly struggling during the experiments to cause the experimental result to be inaccurate; the device can effectively ensure thesmooth progress of the epilepsy research experiments, has the function of collecting mouse urine and oral water, and can prevent the oral water and the urine of the mouse from polluting the laboratoryin the experimental process; the device is safe and reliable, can prevent the mouse from scratching the experimental personnel, has wide application range and can be used for fixing the mice with different sizes.

Description

technical field [0001] The invention relates to the technical field of experimental equipment, in particular to a mouse fixation device for epilepsy research experiments. Background technique [0002] Epilepsy is the second most persistent disease of the nervous system, especially status epilepticus SE, which is a life-threatening emergency with high morbidity and mortality. Currently, the International League Against Epilepsy defines SE as follows: SE refers to a seizure that lasts for more than 30 minutes, or a seizure that lasts for more than 30 minutes, or a seizure that fails to recover consciousness during the intermittent period for more than 30 minutes. In SE, the seizure lasts for a long time without any cessation or recurrence. The state of consciousness does not return to baseline during the second seizure. The mechanism of SE can be considered to be abnormally long (after t1 time) seizures due to the failure of the mechanism to terminate epilepsy or the emergenc...

AI Technical Summary

Problems solved by technology

[0004] In the process of epilepsy research, mice are generally used for experiments, and the mice need to be fixed during the experiment. However, the existing mouse fixing devices are not easy to use, and the effect of fixing the mice is relatively poor, which cannot prevent the mice from being crushed by the head. Death due to injury cannot guarantee the smooth progress of the experiment, and the rats are easy to escape, and the rats struggled a lot during the experiment, resulting in excessive physical exertion of the rats and inaccurate experimental results, which cannot guarantee the smooth progress of the epilepsy experiment. It does not have the function of collecting mouse urine and saliva. During the experiment, the mouse's saliva and urine are easy to pollute the laboratory. The safety performance is poor, and the limbs of the mouse cannot be fixed, which will cause the mouse to scratch the experimenter. The scope of application is small. Cannot be used to immobilize mice of different sizes, for this reason, an experimental mouse immobilization device for epilepsy research is proposed

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