Lipidosome preparation system for laboratory

Abstract

The invention discloses a lipidosome preparation system for a laboratory. The lipidosome preparation system comprises a first blending tank, a second blending tank, a first circulating tank, a secondcirculating tank and lipidosome pelletizing equipment. According to the lipidosome preparation system, in the lipidosome preparation process, all technological process data can be recorded in detail,great reference significance for subsequent amplified production is achieved, and the success possibility of conversion from laboratory research and development to production is increased greatly.

Description

technical field [0001] The invention belongs to the technical field of liposomes, in particular to a laboratory liposome preparation system. Background technique [0002] Liposome technology is currently the main core technology of sustained and controlled release preparations and anti-tumor high-end complex preparations in the pharmaceutical industry. Liposomes are microvesicles with a structure similar to human cell membranes, have very good biocompatibility with the human body, and have the functions of targeting and slow-controlled release in function, so the development in the pharmaceutical industry is very rapid, and it has gradually become a A mainstream complex high-end preparation dosage form. [0003] At present, there is a relatively serious gap between the laboratory research and development of liposomes and the formal production of workshops. At present, the research and development of the laboratory mostly adopts a step-by-step method, and the mode of manual...

AI Technical Summary

Problems solved by technology

[0004] 1. At present, the preparation of liposome samples in the laboratory is a single device with manual operation, which is operated step by step. There is no complete set of equipment or system that can realize all the functions of the system at the same time.

Existing equipment generally can only realize 1 or 2 functions of the system

[0005] 2. Liposome samples prepared in existing laboratories are generally exposed in beakers, and solvent volatilization often leads to environmental pollution and human injury.

Unable to realize the whole process airtight operation

[0006] 3. Most of the liposome operations in the existing laboratory are manual operations, with poor reproducibility and stability, and it is impossible to use the automatic operation of this system in the whole process

[0007] 4. The data of the liposome preparation process in the existing laboratory is manually recorded, with large deviations, which is not conducive to subsequent experimental analysis, and the data is easy to be missed and difficult to save

[0008] 5. Most of the equipment or containers used for preparing liposomes in existing laboratories are made of glass or other materials, and most of the connecting pipelines are hoses, which do not meet the sanitary standards of the pharmaceutical industry and are prone to experiment failure due to bacterial contamination

Images