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A kind of Hericium ergothioneine health product preparation and preparation method thereof

A technology of ergothioneine and Hericium erinaceus, applied in botany equipment and methods, applications, gardening, etc., can solve the problems of long cycle, bacterial contamination, waste, etc.

Active Publication Date: 2022-02-11
BLOOMAGE BIOTECHNOLOGY CORP LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. The traditional solid cultivation technology has a long cycle, cannot expand production, and is difficult to efficiently enrich active products
[0006] 2. Most fermented solid products of Hericium erinaceus only take solid mycelium, and the fermentation broth is discarded, while exopolysaccharides and part of ergothioneine are all present in the fermentation broth, causing waste
[0007] 3. Although Hericium erinaceus fermented liquid products can completely retain the active ingredients, as health care liquid products, the stability is usually poor, and long-term storage will cause deterioration and bacterial contamination, making it difficult to store and apply for a long time
[0008] 4. At present, there is no product with ergothionein as the main functional activity in health care products

Method used

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  • A kind of Hericium ergothioneine health product preparation and preparation method thereof
  • A kind of Hericium ergothioneine health product preparation and preparation method thereof
  • A kind of Hericium ergothioneine health product preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] (1) The strains preserved in test tubes were inoculated into 500 ml of seed culture medium with bacterial blocks, and cultured at 25° C. for 7 days on a shaker at 200 rpm;

[0091]The composition of the seed medium is as follows:

[0092] Glucose 20g / L, yeast powder 20g / L, disodium hydrogen phosphate 0.5g / L, acetic acid to adjust pH to 6.5

[0093] (2) Seed culture medium was inoculated into 15L fermentation medium, 200rpm shaker, cultured at 25°C for 11 days until residual sugar <0.5% fermentation ended;

[0094] The composition of the fermentation medium is as follows:

[0095] Glucose 60g / L, yeast powder 35g / L, sodium sulfate 0.75g / L, disodium hydrogen phosphate 1g / L, zinc chloride 0.005g / L, pyridoxal phosphate 0.001g / L, acetic acid to adjust pH to 5.5, asparagus Amino acid 5mM, glutamine 5mM, histidine, 5mM, betaine 20Mm.

Embodiment 2

[0097] (1) Take 500ml of the fermented liquid that has been fermented in Example 1, homogenize it through a high-pressure homogenizer, the homogenate pressure is 35MPa, and the homogenate time is 20min, add 25g of maltodextrin to the fermented liquid, heat to 50°C and stir Mix well to fully dissolve the excipients;

[0098] (2) The feed liquid is spray-dried, using pressure spraying, the feed rate is 400ml / h, the inlet air temperature is 180°C, and the outlet air temperature is 85°C. Finally, 42g of brown-yellow Hericium erinaceus powder can be obtained, and the liquid phase detection The content of ergothioneine in the bacterial powder was 0.222g / kg.

Embodiment 3

[0100] (1) Get 10L of fermented liquid that fermented in Example 1 and finish, homogenate through high-pressure homogenizer, homogenate pressure is 50MPa, homogenate time is 30min, after homogenization finishes, add maltodextrin 1500g in fermented liquid, heat Stir at 60°C to fully dissolve the excipients;

[0101] (2) The feed liquid is spray-dried, using centrifugal spraying, the feed rate is 2000ml / h, the inlet air temperature is 190°C, and the outlet air temperature is 95°C, finally 2.36kg of light yellow Hericium erinaceus powder can be obtained, liquid phase The content of ergothioneine in the bacterial powder was detected to be 0.146g / kg.

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Abstract

The invention discloses a preparation method of a Hericium ergothioneine health product preparation, which is characterized in that it comprises step 1: inoculating Hericium erinaceus hyphae into a liquid seed medium for cultivation to obtain a seed liquid; step 2 : Inoculate the seed liquid into the fermentation medium to ferment, and ferment to the end point to obtain a fermentation liquid; Step 3: Homogenize the fermentation liquid containing mycelia through a high-pressure homogenizer, add auxiliary materials and mix, and spray dry at high temperature to prepare The obtained powder is used as a Hericium ergothioneine health product preparation containing ergothioneine. The preparation retains the Hericium erinaceus mycelia in the fermentation broth and is also rich in active substances such as fungal exopolysaccharides and ergothioneine synthesized in the fermentation process. It can not only resist oxidation and radiation, but also protect the stomach and nourish the stomach. It can be used as a health care preparation to prepare capsules, granules and other products. The invention is suitable for deep processing and utilization of Hericium erinaceus fermented liquid.

Description

technical field [0001] The invention relates to the field of health products, in particular to a Hericium ergothioneine health product preparation and a preparation method thereof. Background technique [0002] Hericium erinaceum (Hericium erinaceum) belongs to the genus Hericium erinaceae of the order Basidiomycetes, Hericium erinaceae, and is named for its fruiting body resembling a monkey's head. Wild Hericium erinaceus is mainly distributed in the Greater Khingan Mountains in the northeast, the Tianshan Mountains and the Altai Mountains in the northwest, and is also produced in Inner Mongolia, Henan, Hebei, Sichuan, Hubei, Guangxi, Zhejiang, Jiangxi and other provinces. In foreign countries, the United States, Japan, Russia and Western Europe are all produced. As early as I have recorded in the ancient Compendium of Materia Medica, Hericium erinaceus is flat in nature, sweet in taste, and has the functions of benefiting the five internal organs, strengthening the spleen...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/00A23L31/00A01G18/20A01G18/00
CPCA01G18/00A01G18/20A23L33/00A23L31/00
Inventor 陆震魏玉洁贾玉倩石艳丽郭学平栾贻宏
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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