10 results about "Hericium erinaceum" patented technology

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

This invention discloses a low glycemic index (GI) Hericium erinaceus (monkey head mushroom) steamed bun, belonging to the field of food processing and functional food applications. By weight, it is prepared from the following raw materials: 45-55 parts all-purpose flour, 28-35 parts Hericium erinaceus extract powder, 0.3-0.35 parts yeast, 15-18 parts water, 0.3-0.6 parts oil, and 0.7-0.9 parts sugar. This invention partially replaces the flour with Hericium erinaceus extract powder, fully utilizing the multiple mechanisms of action of Hericium erinaceus polysaccharides in forming a viscous gel in the digestive tract to slow down the contact between amylase and substrate, inhibiting α-amylase and α-glucosidase activity, and improving intestinal microecology and enhancing insulin sensitivity through dietary fiber. This allows the product to meet the low-GI food standard (GI<55), effectively filling the gap in low-GI steamed buns with Hericium erinaceus functional components as the core active ingredient. It has significant application value in the fields of diabetes management, weight control, and healthy staple foods.

The application relates to the field of biological transformation, and particularly discloses a spleen and stomach health type biological transformation beverage and a preparation method thereof. The spleen and stomach health type biological transformation beverage comprises a fermentation liquor, concentrated apple juice, xylitol and stevioside, the raw materials of the fermentation liquor comprise Hericium erinaceus, ginseng, Poria cocos, Myristica fragrans (fried), Chinese yam, Lablab albumus (fried), lotus seed, Coix lachryma-jobi (fried), Amomum villosum, licorice and water, and the fermentation liquor is formed by biological transformation of the raw materials under the action of compound probiotics. The fermentation raw materials of the application modify the traditional ancient prescription of Shenlingbaizhu powder, increase the Hericium erinaceus which is commonly seen and low-fat and high-protein, combine common food and medicine-food homologous substances, are suitable for people with weak spleen and stomach, indigestion and diabetes, and have the advantages of richer nutrition, long-term edible, no toxic and side effects, healthy spleen and stomach and promotion of intestinal peristalsis.

This invention provides a composition comprising: 5-15 parts by weight of dried plum, 10-20 parts by weight of cinnamon twig, 10-20 parts by weight of ginseng, 3-8 parts by weight of angelica root, 5-15 parts by weight of asarum, 10-30 parts by weight of dried ginger, 5-15 parts by weight of Sichuan pepper, 5-15 parts by weight of phellodendron bark, 3-8 parts by weight of coptis root, 20-40 parts by weight of bitter wine, 20-30 parts by weight of japonica rice, 10-20 parts by weight of honey, 3-8 parts by weight of lily bulb, 40-60 parts by weight of polygonum multiflorum stem, 40-60 parts by weight of monkey head mushroom, 3-8 parts by weight of polygala root, and 5-15 parts by weight of poria cocos (a traditional Chinese medicine composition). Further, the composition comprises: 20-40 parts by weight of hydrolyzed milk protein, 20-40 parts by weight of fish collagen peptide, and 20-40 parts by weight of soybean peptide (a biological product). This invention also provides pharmaceutical preparations (especially pills) comprising the above composition, biological products, and methods for preparing the same. The composition has a significant effect on improving sleep and has broad application prospects.

The present application relates to the technical field of plant extract, and discloses a preparation method of Hericium erinaceus extract and application of the Hericium erinaceus extract in cosmetics, which comprises the following steps: taking Hericium erinaceus raw materials, adopting ethanol reflux extraction, combining the extraction liquid, and obtaining extract by vacuum concentration; liquid-liquid extraction is carried out by using ethyl acetate, and the Hericium erinaceus extract is obtained by concentration and freeze-drying. The main active ingredient of Hericium erinaceus extract is Hericenones C by HPLC separation. The activity verification experiment shows that the extract has significant antioxidant activity, the IC50 value of DPPH free radical scavenging capacity is 239±7 μg / mL; the IC50 value of hydroxyl radical (·OH) scavenging capacity is 547±15 μg / mL; the Trolox equivalent antioxidant capacity (TEAC) of ABTS+· free radical scavenging capacity is 477.3±3.1 μmol TE / g; the extract has significant proliferation promoting effect on HaCaT cells, and the maximum proliferation rate is 146.44±1.27%. The present application solves the technical problems that the components of Hericium erinaceus extract are not clear and the UVB resistance activity is not developed, and provides a technical basis for the application of the extract in cosmetics as anti-wrinkle, repair and anti-aging raw materials.

This invention discloses a glycosylated polypeptide extract from Hericium erinaceus, its preparation method, and its applications, belonging to the technical field of Hericium erinaceus extracts. The technical solution includes: alkaline extraction, where Hericium erinaceus waste powder is subjected to alkaline extraction; the pH of the resulting extract is adjusted to the isoelectric point of Hericium erinaceus protein; the precipitate is repeatedly washed until neutral to obtain Hericium erinaceus protein and polysaccharide precipitates; enzymatic hydrolysis, where the Hericium erinaceus protein and polysaccharide precipitates are added to water, and an enzyme preparation is added for enzymatic hydrolysis to obtain an enzymatic hydrolysate of Hericium erinaceus polypeptides and polysaccharides; polypeptide glycosylation modification, where the enzymatic hydrolysate of Hericium erinaceus polypeptides and polysaccharides undergoes a gradient temperature-changing cyclic CO2-assisted catalytic glycosylation reaction; after the reaction, freeze-drying yields the Hericium erinaceus glycosylated polypeptide extract. This invention enables the resource utilization of Hericium erinaceus waste, while simultaneously preparing a highly active, highly stable glycosylated polypeptide extract that improves the water solubility of lipid-soluble extracts, reducing production costs and expanding its application range.

This invention discloses a simulated steak based on Hericium erinaceus fruiting bodies and its preparation method. The method includes the following steps: taking frozen Hericium erinaceus and thawing it; staining the thawed Hericium erinaceus fruiting bodies with an aqueous solution of edible pigment; marinating the dyed Hericium erinaceus fruiting bodies in a braising liquid; and deep-frying and pan-frying the marinated Hericium erinaceus fruiting bodies to obtain the simulated steak based on Hericium erinaceus fruiting bodies. This invention uses Hericium erinaceus fruiting bodies as raw material to prepare simulated steak. The fruiting bodies have abundant fine fibers, which can better simulate meat fibers and provide a chewy texture. They also contain a large amount of umami amino acids, providing a rich flavor experience. The rehydration, thawing, marinating, and deep-frying processes of Hericium erinaceus fruiting bodies can remove most of the bitterness of the mushrooms, resulting in a better flavor compared to plant-based steaks and Hericium erinaceus steaks that are not rehydrated, thawed, or deep-fried. Hericium erinaceus has a short growth cycle, requires little land resources, and is environmentally friendly.

This invention discloses a method for fermenting Dendrobium officinale using Hericium erinaceus, the preparation of the resulting fermented traditional Chinese medicine complex, and its applications. It belongs to the field of microbial fermentation of traditional Chinese medicine, and particularly relates to a method for fermenting Dendrobium officinale using Hericium erinaceus, comprising: activating and culturing Hericium erinaceus to obtain an activated strain; culturing the activated strain in a seed culture medium to obtain a liquid inoculum; inoculating the liquid inoculum into a co-fermentation culture medium for co-fermentation to obtain a fermentation broth; adding zinc acetate; heating and incubating at a static temperature to obtain a primary product; drying to obtain the fermented traditional Chinese medicine complex. The method for fermenting Dendrobium officinale using Hericium erinaceus and the preparation of the fermented traditional Chinese medicine complex proposed in this invention, by adding vitamin B1 and zinc acetate, result in a fermented traditional Chinese medicine complex with high polysaccharide content and good high-temperature stability, solving the problems of low polysaccharide yield and low activity retention rate after high-temperature processing in the Hericium erinaceus-Dendrobium co-fermentation product.

This invention discloses a composition and its application in anti-tumor, anti-cellular aging, anti-wrinkle, and auxiliary reduction of uric acid. The composition comprises: dihydroquercetin, yeast powder, ginsenosides, astragalus extract, brown algae polysaccharide, purslane extract, polygonatum extract, agaricus blazei extract, hericium erinaceus extract, Omega-3 fatty acids, docosahexaenoic acid (DHA), raspberry peptide, dihydromyricetin, cinnamon powder extract, cornus officinalis extract, rehmannia glutinosa extract, yam extract, wolfberry extract, moringa leaf extract, sunflower disc peptide, euglena julibrissin extract, Dunaliella salina extract, poria cocos extract, dendrobium officinale extract, ophiopogon japonicus extract, and collagen peptides.

This invention discloses an HPLC method for simultaneously determining the content of six active ingredients in Hericium erinaceus extract, belonging to the field of natural compound detection and analysis technology. The detection steps of this invention include: preparing a mixed standard solution using Hericium erinaceus ketone E, Hericium erinaceus ketone C, Hericium erinaceus ketone D, Hericium erinaceus D, ergosterol, and Hericium erinaceus C as reference standards; analyzing the mixed standard solution using high-performance liquid chromatography (HPLC); plotting standard curves for the six active ingredients with the concentration of the mixed standard solution as the abscissa and the peak area as the ordinate; determining the linear regression equation; and calculating the content of each active ingredient in the sample solution. The HPLC method for simultaneously determining six active ingredients in Hericium erinaceus extract established in this invention has good selectivity, high sensitivity, accuracy, and reliability, providing a new analytical method and basis for the quality analysis and quality control of Hericium erinaceus extract.