Testing method for judgment standard of drug tolerance of mycoplasma gallisepticum to tylosin

Abstract

The invention discloses a testing method for a judgment standard of the drug tolerance of mycoplasma gallisepticum to tylosin. The testing method comprises the steps of building a detection method forthe drug tolerance of the mycoplasma gallisepticum to the tylosin, setting a wild type critical value of the tylosin to the mycoplasma gallisepticum, setting a pharmacodynamics critical value of thetylosin to the mycoplasma gallisepticum, setting a clinical critical value of the tylosin to the mycoplasma gallisepticum and a flow diagram drawn according to inflection points published in CLSI, wherein when the condition that COWT is higher than COPD, and the COPD is higher than COCL, the corresponding inflection point ought to select the wild type critical value, and then the judgment standardof the drug tolerance of the mycoplasma gallisepticum to the tylosin is obtained. By using the method, the judgment standard of the drug tolerance of the mycoplasma gallisepticum to the tylosin can be obtained, a stable medication data support can be provided for scientific farming, clinical medication can be more scientifically guided, the safety is high, and the drug tolerance of the mycoplasmagallisepticum to the tylosin can be effectively retarded, and the effectiveness of the tylosin is protected and maintained.

Description

technical field [0001] The invention relates to the technical field of drug resistance judgment, in particular to a standard test method for the drug resistance judgment of mycoplasma gallisepticum to tylosin. Background technique [0002] Mycoplasma that infects chickens is mainly divided into Mycoplasma gallisepticum and Mycoplasma gallisepticum. Mycoplasma gallisepticum, also known as Mycoplasma gallisepticum, mainly infects chickens and turkeys, causing chronic respiratory infectious diseases in chickens , while mycoplasma synovium infects chickens to cause symptoms such as arthritis. As a special drug for animals, tylosin has a good therapeutic effect on respiratory diseases of livestock and poultry, and it is not easy to produce drug residues, and its toxicity is weak. The extremely high safety further promotes its clinical application in veterinary medicine. [0003] The irrational use of drugs in the breeding industry in my country has led to the emergence of drug r...

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Problems solved by technology

[0003] The irrational use of drugs in the breeding industry in my country has led to the emergence of drug resistance. Drug resistance detection is necessary and urgent. In order to slow down the resistance of Mycoplasma gallisepticum to tylosin, protect and maintain the production of tylosin. Effectiveness, it is necessary to carry out drug resistance monitoring measures for Mycoplasma gallisepticum. The drug resistance determination standard is a scientific means for effective drug resistance monitoring of bacteria and a scientific criterion for judging bacterial drug resistance. In order to monitor drug resistance, analyze drug resistance Present situation and development law, more scientific guidance clinical medication, the present invention proposes the standard test method of the drug resistance determination of Mycoplasma gallisepticum to tylosin, to solve the deficiencies in the prior art

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