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Method for randomly filling tumor with radioactive particle source

A technology of radioactive particles and random filling, applied in radiation therapy, X-ray/γ-ray/particle irradiation therapy, treatment, etc., can solve the problems of normal tissue damage, poor therapeutic effect of radioactive particle source, etc., and achieve the best therapeutic effect Effect

Inactive Publication Date: 2019-09-13
成都真实维度科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional particle layout method does not fully consider the optimal position of the radioactive particle source. The therapeutic effect of the radioactive particle source placed in this position is poor, and it will cause great damage to normal tissues.

Method used

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  • Method for randomly filling tumor with radioactive particle source
  • Method for randomly filling tumor with radioactive particle source
  • Method for randomly filling tumor with radioactive particle source

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0050] Such as figure 1 As shown, the radioactive particle source random filling method in the tumor of this embodiment includes the following steps:

[0051] S101. Extracting the tumor, the tumor is a segmented tumor surface drawing model;

[0052] S102. Generate a virtual box that matches the maximum length, width, and height of the tumor, embed the tumor in the virtual box, randomly generate a sphere with a radius of 1 cm (effective radiation range) in the virtual box, a sphere, etc. function as a source of radioactive particles;

[0053] S103. The generated sphere with a radius of 1 cm (effective radiation range) uniformly releases rays from the center point to the surroundings, and detects whether each ray intersects with the surface of the tumor. If so, it proves that the sphere is located inside the tumor and is an effective sphere, so keep the sphere. If otherwise, it is proved that the sphere is not completely located inside the tumor, which is an invalid sphere, an...

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PUM

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Abstract

The invention discloses a method for randomly filling tumor with radioactive particle sources. The method comprises the following steps: S101, extracting tumor; S102, generating a virtual square box body matching with the maximum length, width and height of the tumor, embedding the tumor in the virtual square box body, and randomly generating spheres with a radius of Vcm in the virtual square boxbody, wherein each sphere is equivalent to a radioactive particle source; and S103, uniformly releasing rays from the central point to the periphery of the generated spheres with the radius of Vcm, detecting whether each ray intersects with the surface of the tumor, if proving that one sphere is positioned inside the tumor and is an effective sphere, reserving the sphere, if proving that the sphere is not completely positioned inside the tumor and is an invalid sphere, deleting the sphere, and stopping the operation until the number of the spheres reaches the total number of radioactive particle sources required by the tumor. According to the radioactive particle sources which are randomly filled with in the invention, the method fully considers the optimal position of the radioactive particle sources, and the radioactive particle sources which are arranged at the positions have the best treatment effect and do not cause great damage to normal tissues.

Description

technical field [0001] The invention belongs to the technical field of radioactive particle implantation, and in particular relates to a random filling method of a radioactive particle source in a tumor. Background technique [0002] Interstitial radioactive seed implantation (also known as brachytherapy) therapy is to implant micro-radiation sources (particles) into tumors or tissues infiltrated by tumors, including tissues where malignant tumors spread along the lymphatic pathway, and emit radioactive particles through the source of radioactive particles. Continuous low-energy γ-rays cause tumor tissue to suffer maximum radiation damage and destruction, while normal tissue is not damaged or only slightly damaged, so as to achieve the purpose of treatment. According to the seed implantation time, it can be divided into permanent implantation method and non-permanent implantation method. Experts believe that compared with other tumor treatment techniques, radioactive seed i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1007A61N5/103A61N2005/1024
Inventor 张翔毛瑞军孟群曲飞寰石广越
Owner 成都真实维度科技有限公司