Inert carrier Escherichia coli and its potential application

A technology of Escherichia coli and an inert carrier, applied to the inert carrier Escherichia coli and its potential application fields, can solve the problems of affecting the purification effect of epidemic diseases, and interfere with the results of detection and diagnosis, and achieve great application value and market prospects. The effect of specific bottlenecks
CN110257276AActive Publication Date: 2019-09-20YANGZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
YANGZHOU UNIV
Publication Date
2019-09-20

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Abstract

The present invention relates to an inert carrier Escherichia coli and its potential application, the Escherichia coli isolated strain has the inert carrier property, and is expected to be developed into a carrier strain for an indirect agglutination test. The inert carrier Escherichia coli is preserved in the China General Microorganisms Collection and Management Center (CGMCC), and a preservation address is Beijing, China, a preservation number is CGMCC No. 17339, a preservation date is March 18, 2019, a classification name is Escherichia coli, and a strain code is SE1. The Escherichia coli isolated strain is from a healthy flock, the bacteria number at a higher working concentration does not cause any macroscopic agglutination reaction with various chicken serums of different genetic backgrounds, and does not generate non-specific agglutination reaction with chicken source serum, so that the Escherichia coli is called as an inert carrier Escherichia coli. The application provides an inert carrier strain and its potential application for developing a simple and rapid indirect agglutination assay.
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Description

[0001] field of invention

[0002] The invention belongs to the field of biotechnology detection, and relates to an inert carrier Escherichia coli, its isolation and identification and its application. In view of the fact that the number of bacteria in the working concentration of this carrier Escherichia coli does not occur in non-specific agglutination reaction of chicken source serum, and its It provides an inert carrier and has potential application prospects in the development of an indirect agglutination test method for the simple and rapid detection of antigens or infection antibodies. Background technique

[0003] The development of immunology provides many technical methods for the simple and rapid detection of pathogenic bacteria in clinical practice. Among them, agglutination test is a traditional and classic rapid diagnosis method for epidemic diseases widely used in medical and veterinary clinics. After the antigen is combined with the corresponding antibody, when...

Claims

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