Afterload device for isolated heart perfusion
An afterload, cardiac technology, applied in the field of biomedical engineering, can solve problems affecting cardiac function, affecting the quality of perfusion, etc.
Active Publication Date: 2019-10-11
SHANGHAI UNIV
View PDF5 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
In the isolated perfusion system, the blood vessels are replaced by medical tubing. When the blood is pumped out, it flows back to the heart without encountering any resistance. This is significantly different from the actual physiological conditions in the body. The degree of afterload of the heart will vary. Directly affect the function of the heart and affect the quality of perfusion
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0026] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
[0027] The object of the present invention is to provide an afterload device for isolated heart perfusion to solve the above-mentioned problems in the prior art, which can provide the resistance encountered when the blood is pumped out, and simulate the normal working mode of the heart in the body.
[0028] In order to make the above objects, features and advantages of the present invention more comprehensible, the present invention will be further described in...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention discloses an afterload device for isolated heart perfusion. The afterload device comprises an afterload energy storage module, a gas pressure regulating module and two flow rate regulators, which are connected through a pipeline. The afterload energy storage module comprises a rigid closed container and a flexible container, perfusate flows in from one side of the flexible containerthrough the pipeline, the flexible container is subjected to the pressure of a medium in the rigid closed container, and the perfusate flows out from the other side. The pressure regulating module comprises two pressure regulating valves and a compressible medium source and is used for regulating the pressure in the rigid closed container to maintain the pressure between set diastolic blood pressure and set systolic blood pressure all the time. Under the pressure action, liquid in the flexible container is pressed, the afterload in isolated heart perfusion is provided, the isolated heart perfusion can better meet physiological conditions, and the perfusion quality is improved.
Description
technical field [0001] The invention relates to the technical field of biomedical engineering, in particular to an afterload device for isolated heart perfusion. Background technique [0002] Isolated heart perfusion (ESHP) is an effective method that can facilitate donor heart preservation and functional assessment. Using this technique not only enables ex vivo evaluation of dysfunctional donor hearts, but also enables ex vivo repair of poorer quality hearts to alter their properties, thereby expanding the donor pool. [0003] Perfusion of the isolated heart was first proposed by Oscar Langendorff in the late 19th century. In the traditional Langendorff perfusion mode, the perfusion fluid is reversely perfused through the cardiac aortic cannula. Due to the effect of the perfusion hydraulic pressure, the aortic valve is closed and the perfusion fluid flows into the coronary artery. The heart provides the oxygen and energy that keep the heart beating for hours. [0004] Thi...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/02
CPCA01N1/0247A01N1/0273
Inventor 彭艳徐志兵辛立明罗均谢少荣蒲华燕高守玮米特什·巴迪瓦拉孙钰
Owner SHANGHAI UNIV