A kind of compound spray film agent for dairy cows and preparation method thereof

A technology for spraying film and compound recipes, which can be applied to medical preparations without active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems of slow curative effect, poor curative effect, and inability to treat, and achieve a high cure rate. , No sag, good for absorption

Active Publication Date: 2021-10-19
ZHENGZHOU BARY ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to solve the problem of poor curative effect and slow curative effect of the traditional Chinese medicine spray film agent and the problem that the single-component povidone can only prevent cow mastitis and cannot treat it, and propose a compound spray film agent for dairy cows and its preparation method

Method used

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  • A kind of compound spray film agent for dairy cows and preparation method thereof
  • A kind of compound spray film agent for dairy cows and preparation method thereof
  • A kind of compound spray film agent for dairy cows and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment one kind of compound spray film agent for cows, this film spray agent is made of the following components by weight: 5 parts of povidone iodine, 2 parts of clove oil, 5 parts of dimethyl sulfone, PVB (polyvinyl alcohol Butyral) 7 parts, HPMC E5 (hydroxypropyl methylcellulose) 2 parts, 2 parts of propylene glycol, 1 part of menthol, 1 part of azone, 75 parts of the mixture of purified water and 95% ethanol (the ratio of the two is 1:8).

[0024] The preparation method of the above-mentioned compound spray film agent for cows comprises the following steps: taking each raw material according to the above parts by weight, dissolving PVB into 95% ethanol of 50% prescription amount to obtain solution A; mixing clove oil, menthol, azone Add propylene glycol and 95% ethanol to 50% prescription amount and stir to obtain a clear solution, then add HPMC E5 to obtain a suspension solution B; dissolve dimethyl sulfone in purified water, add povidone-iodine and stir to dispe...

Embodiment 2

[0025] Embodiment two a kind of compound spray film agent for cows, this film spray agent is made of the following components by weight: 5 parts of povidone iodine, 2 parts of clove oil, 5 parts of dimethyl sulfone, PVB (polyvinyl alcohol 4 parts of butyral), 1 part of HPMC E5 (hydroxypropyl methylcellulose), 2 parts of propylene glycol, 1 part of borneol, 1 part of azone, 79 parts of a mixture of purified water and 95% ethanol (the ratio of the two is 1 :8).

[0026] The preparation method of the above-mentioned compound spray film agent for cows comprises the following steps: taking each raw material according to the above parts by weight, dissolving PVB into 95% ethanol of 50% prescription amount to obtain solution A; mixing clove oil, borneol, azone and Add propylene glycol to 95% ethanol with 50% prescription quantity and stir to obtain a clear solution, then add HPMC E5 to obtain a suspension solution B; dissolve dimethyl sulfone in purified water, add povidone-iodine an...

Embodiment 3

[0027] Embodiment three a kind of compound spray film agent for cows, this film spray agent is made of the following components by weight: 5 parts of povidone iodine, 2 parts of clove oil, 5 parts of dimethyl sulfone, PVB (polyvinyl alcohol Butyral) 6 parts, HPMC E5 (hydroxypropyl methylcellulose) 1.5 parts, propylene glycol 2 parts, borneol 1 part, menthol 0.5 part, azone 1 part, 79 parts of the mixture of purified water and 95% ethanol ( The ratio of the two is 1:8).

[0028] The preparation method of the above-mentioned compound spray film agent for cows comprises the following steps: taking each raw material according to the above parts by weight, dissolving PVB into 95% ethanol of 50% prescription amount to obtain solution A; mixing clove oil, borneol, menthol, Add azone and propylene glycol to 95% ethanol of 50% recipe quantity and stir to obtain a clear solution, then add HPMC E5 to obtain a suspension solution B; dissolve dimethyl sulfone in purified water, add povidon...

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Abstract

The invention belongs to the technical field of veterinary drug preparations, and discloses a compound spray film agent for cows, which is made of the following components in parts by weight: 1-5 parts of povidone-iodine, 0.1-2 parts of clove oil, two 2-8 parts of methyl sulfone, 3-10 parts of film-forming agent, 0.5-2 parts of thickener, 0.5-2 parts of humectant, 0.5-2.5 parts of transdermal absorption accelerator, 70-90 parts of solvent; the solvent It is a mixture of alcoholic solvents and aqueous solvents. The compound spray film agent of the present invention uses povidone iodine, clove oil, borneol / menthol, and dimethyl sulfone as the composite components of the principal agent, and dimethyl sulfone is applied to the film spray agent for cow mastitis for the first time to improve poly Povidone iodine and clove essential oil’s antibacterial and disinfection ability can promote the healing of dairy cow udder wounds, and solve the problem that traditional spraying agents only use povidone iodine single preparation and can only prevent dairy cow mastitis but cannot treat it; compared with other dairy cow mastitis The preparation for external use is evenly coated, the film-forming speed is fast, there is no sagging or dripping phenomenon, the effect of promoting wound healing is obvious, and the healing rate is high.

Description

technical field [0001] The invention belongs to the technical field of veterinary drug preparations, and in particular relates to a compound spray film agent for cows and a preparation method thereof. Background technique [0002] Cow mastitis is mainly caused by various pathogenic microorganisms such as Staphylococcus aureus, Streptococcus, Escherichia coli, etc. It will affect the quality of dairy products and endanger food hygiene and safety. The dosage forms for preventing and treating dairy cow mastitis mainly include injections, infusions, powders, and transdermal preparations. Transdermal preparations can be divided into cataplasms, coatings, sprays, sprays, etc. according to different drug carriers. (1) Catapults: Catalysts refer to external dosage forms in which drugs are dissolved or mixed in a water-soluble polymer matrix and spread on the backing material for skin sticking. The cataplasm has good adhesion to the skin, and it is clean and has no residue when it...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K36/61A61K47/38A61K47/32A61P15/14A61P31/04A61K31/045A61K31/10A61K31/79
CPCA61K9/7015A61K31/045A61K31/10A61K31/79A61K36/61A61K47/32A61K47/38A61P15/14A61P31/04A61K2300/00
Inventor 陈长青刘示范丁佳丽周衡崔小七陈盟梁桂霞
Owner ZHENGZHOU BARY ANIMAL PHARMA
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