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A kind of preparation method of nourishing yin and clearing lung oral liquid

An oral liquid and lung-clearing technology, which is applied in the field of preparation of Yangyin Qingfei oral liquid, can solve the problems of less than 30%, and achieve the effects of increasing the content, improving the curative effect of the drug, and improving the work efficiency

Active Publication Date: 2021-06-11
HULUNBEIER SONGLU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies have shown that this method adds the volatile components of Moutan Cortex and Mentha. During the filtration process, it is found that the crystallization of the volatile components of Moutan Cortex and Mentha is filtered out, making the transfer rate of volatile components such as paeonol less than 30%

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1 (calculated by preparing 1000ml)

[0031] Prescription: Rehmannia 80g, Fritillaria 50g, Ophiopogon japonicus 60g, Paeoniae Alba 40g, Scrophulariae 80g, Licorice 30g, Mint 20g, Cortex Moutan 40g, Sucrose 90g, Sorbic acid 0.51g, Polysorbate-80 0.5ml.

[0032] Preparation:

[0033] 1. Take the prescription amount of Fritillaria chinensis, soak it in 70% ethanol for 18 hours, then percolate slowly at a rate of 1-3ml per minute, until the percolation liquid is colorless, collect the percolation liquid, recover ethanol, and get Fritillaria sichuan extract, spare;

[0034] 2. Take the prescribed amount of cortex moutan and peppermint and place it in an extractor after wetting it with water, distill it with water steam, collect 1000ml of distillate, let it cool, take out the volatile components, and store them in another container to obtain the distillate and volatile components of cortex moutan and mint. ingredients, spare;

[0035] 3. Take the dregs extracted ...

Embodiment 2

[0039] Embodiment 2 (calculate by preparing 1000ml)

[0040] Prescription: Rehmannia 120g, Fritillaria 50g, Ophiopogon japonicus 70g, Paeoniae Alba 40g, Scrophulariae 80g, Licorice 20g, Mint 25g, Cortex Moutan 50g, Sucrose 80g, Sorbic acid 1.0g, Polysorbate-80 0.8ml.

[0041] Preparation:

[0042]1. Take the prescription amount of Fritillaria chinensis, soak it in 70% ethanol for 18 hours, then percolate slowly at a rate of 1-3ml per minute, until the percolation liquid is colorless, collect the percolation liquid, recover ethanol, and get Fritillaria sichuan extract, spare;

[0043] 2. Take the prescribed amount of peony cortex and peppermint, put it in the extractor after wetting it with water, distill it with water steam, collect 800ml of distillate, let it cool, take out the volatile components, and store it in another container to obtain the distillate and volatile oil of peony cortex and mint Sexual ingredients, spare;

[0044] 3. Take the dregs extracted from Moutan ...

Embodiment 3

[0048] Embodiment 3: (preparation 1000ml)

[0049] 1. Take 40g of Fritillaria chinensis, impregnate it with 70% ethanol for 18 hours, then percolate slowly at a rate of 1-3ml per minute, until the percolation liquid is colorless, collect the percolation liquid, recover ethanol, and extract Fritillaria sichuanensis ,spare;

[0050] 2. Take 40g of Moutan cortex and 25g of mint, put them in the extractor after wetting them with water, distill with water steam, collect 800ml of distillate, let it cool, take out the volatile components, and store them in another container to obtain the distillate and volatile components of Moutan cortex and mint. ingredients, spare;

[0051] 3. Take the medicinal dregs extracted from Moutan cortex and mint, 100g of Rehmannia glutinosa, 60g of Radix Ophiopogon japonicus, 40g of Radix Paeoniae Alba, 80g of Radix Scrophulariae, 20g of licorice, add water and decoct twice, each time for 2 hours, combine the decoction, and stand at 18°C For 24 hours, ...

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PUM

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Abstract

The preparation method of a kind of nourishing yin and clearing lung oral liquid of the present invention, put peony cortex and peppermint in the extractor after being moistened with water, carry out extraction volatile component by distillation method, in addition, a certain amount of polysorbate-80 is mixed with a small amount of water After dissolving, add the volatile components of peony cortex and peppermint, stir until the volatile components are all dissolved, and then mix with other extracts and flavoring agents to prepare. The method for extraction and preparation improves work efficiency, reduces energy consumption, increases the content of volatile components extracted from cortex moutan and peppermint in the medicinal liquid, and increases the curative effect of the medicine.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a preparation method of an oral liquid for nourishing yin and clearing lung. Background technique [0002] Yangyin Qingfei Oral Liquid is recorded in the first part of the "Chinese Pharmacopoeia" 2015 edition. It has the functions of nourishing yin and moistening lung, clearing lung and relieving throat. For yin deficiency and dryness of the lung, dry throat, dry cough with little phlegm, or bloody phlegm. The product is composed of eight medicinal herbs of rehmannia glutinosa, Fritillaria chinensis, Ophiopogon japonicus, Radix Paeoniae Alba, Scrophulariae scrophulariae, licorice, mint and Moutan bark. Slowly infiltrate at a rate of 1-3ml per minute, and collect the filtrate after the soluble components are completely expelled, and recover ethanol. Moutan cortex and peppermint were distilled with water steam respectively, and 400ml ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/08A61P11/00
CPCA61K9/0095A61K9/08A61K36/484A61K36/534A61K36/65A61K36/71A61K36/804A61K36/808A61K36/8966A61K36/8968A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P11/00A61K2300/00
Inventor 王延辉阎星如孙继春
Owner HULUNBEIER SONGLU PHARMA