Nanometer povidone iodine oral liquid for protecting pig stomach intestines and preparation method for nanometer povidone iodine oral liquid

A povidone-iodine oral liquid, a technology for protecting pigs, which is applied in the directions of medical preparations with non-active ingredients, medical preparations containing active ingredients, pharmaceutical formulas, etc. Tao effect

Inactive Publication Date: 2019-12-31
HUBEI LITAK BIOLOGICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies of the prior art, the invention provides a nanopovidone-iodine oral liquid for protecting the gastrointestinal tract of pigs and a preparation method thereof, which solves the problem of the stability, effectiveness and safety of the existing iodine oral liquid for protecting the gastrointestinal tract of pigs. Non-toxicity, no residue and no drug withdrawal period, it improves the bactericidal ability of pig gastrointestinal tract, and can promote the digestive function of pig gastrointestinal tract, the preparation process is simple, and the cost is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] S1. First, put 20% povidone, 4.5% iodine and 2.1% hawthorn slices into the container respectively, fully soak, react, stir, dry, grind, extract and heat , complexation;

[0032] S2. Prepare deionized water with a corresponding proportion of 69.4%, add the complexed solid in S1 into deionized water, use a vibrating tank to fully vibrate and stir it, and after the powder is completely dissolved, add the corresponding deionized water to the deionized water mixture. Proportioning 1.3% edible glycerin and 2.7% potassium iodide, use a stirring rod to stir it for the second time, make it completely mixed in the double-cone double-helix steam tank and heat to 55°C, and continuously circulate between 55°C for three times, Thereby obtain nanopovidone-iodine oral liquid;

[0033] S3. Use a fully automatic liquid filling machine to cool the nano-povidone-iodine oral liquid to be prepared in S2 to room temperature for filling, and finally label and pack.

Embodiment 2

[0035] S1. Firstly put 23% povidone, 5% iodine and 2.8% hawthorn slices into the container respectively, fully soak, react, stir, dry, grind, extract and heat , complexation;

[0036] S2. Prepare deionized water with a corresponding ratio of 64%, add the complexed solid in S1 into deionized water, use a vibrating tank to fully vibrate and stir it, and after the powder is completely dissolved, add the corresponding deionized water to the deionized water mixture. Proportioning 2% edible glycerin and 3.2% potassium iodide, use a stirring rod to stir it for the second time, make it completely mixed in the double-cone double-helix steam tank and heat to 65°C, and continuously circulate between 65°C for three times, Thereby obtain nanopovidone-iodine oral liquid;

[0037] S3. Use a fully automatic liquid filling machine to cool the nano-povidone-iodine oral liquid to be prepared in S2 to room temperature for filling, and finally label and pack.

Embodiment 3

[0039] S1. Firstly put 25% povidone, 5.6% iodine and 2.1% hawthorn slices into the container respectively, fully soak, react, stir, dry, grind, extract and heat , complexation;

[0040]S2. Prepare deionized water with a corresponding proportion of 63.3%, add the complexed solid in S1 into deionized water, use a vibrating tank to fully vibrate and stir it, and after the powder is completely dissolved, add the corresponding deionized water to the deionized water mixture. Proportioning 1.3% edible glycerin and 2.7% potassium iodide, use a stirring rod to stir it for the second time, make it completely mixed in the double-cone double-helix steam tank and heat to 75°C, and continue to circulate between 75°C for three times, Thereby obtain nanopovidone-iodine oral liquid;

[0041] S3. Use a fully automatic liquid filling machine to cool the nano-povidone-iodine oral liquid to be prepared in S2 to room temperature for filling, and finally label and pack.

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PUM

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Abstract

The invention discloses a nanometer povidone iodine oral liquid for protecting pig stomach intestines and a preparation method for the nanometer povidone iodine oral liquid. The nanometer povidone iodine oral liquid is prepared from the following raw materials in percentage by weight: 20-25 percent of povidone, 4.5-5.6 percent of iodine, 1.3-2.5 percent of edible glycerin, 2.1-3.1 percent of haw slice, 2.7-3.6 percent of potassium iodide and 65-80 percent of deionized water. The invention relates to the technical field of veterinary drugs and pharmacy. For the nanometer povidone iodine oral liquid for protecting the pig stomach intestines and the preparation method, proteins in the bacteria are directly denatured and precipitated by releasing effective iodine by povidone iodine of nano-scale particles, so that pathogenic microorganisms die, efficient disinfection and sterilization are realized, the protection effect to the pig stomach intestines is exerted, the resistance and the immunity of a pig are improved, and the death rate is lowered; the production process is simple and scientific, soaking, reaction, stirring, drying, grinding, extraction, heating, complexing, dilution, filling are accomplished at a stretch, less power is consumed, and the labor is saved; and The nanometer povidone iodine oral liquid for protecting the pig stomach intestines is environmentally friendlywithout any residue, is zero to the withdrawal time and large in market space, is directly diluted and used and is simple and quick to operate for a user.

Description

technical field [0001] The invention relates to the technical field of veterinary medicine and pharmacy, in particular to a nano-povidone-iodine oral liquid for protecting the stomach and intestines of pigs and a preparation method thereof. Background technique [0002] Stomach is the source of all diseases in animals, and the health of pig stomach directly affects the incidence of pigs. Early porcine infectious gastroenteritis is caused by porcine transmissible gastroenteritis virus of bacteria and coronavirus. It is an acute and highly contagious mucosal and intestinal infectious disease, characterized by high fever, vomiting, severe diarrhea, and dehydration. [0003] Povidone-iodine is a loose complex formed by the combination of elemental iodine and a polymer carrier. Povidone acts as a carrier and a solubilizer. It is a yellow-brown to brown-red amorphous powder at room temperature. It has a slight odor and is easily soluble in water. Or ethanol, the aqueous solution ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K33/18A61K9/08A61K47/02A61K47/10A61K47/58A61P1/00A61P31/00
CPCA61K9/0095A61K33/18A61K36/734A61K47/02A61K47/10A61K47/58A61P1/00A61P31/00A61K2300/00
Inventor 邓鸣飞
Owner HUBEI LITAK BIOLOGICAL ENG CO LTD
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