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Channel dredging and collateral activating cervical vertebra sticking-plaster formula and preparation method of cervical vertebra sticking-plaster

A technology of dredging meridian and activating collaterals and cervical spine paste, which is applied in the field of cervical spine paste, can solve the problems of limited penetration of active substances into the skin and unsatisfactory curative effect, and achieve the effects of promoting skin absorption rate, relieving anxiety, and enhancing efficacy

Active Publication Date: 2020-02-28
FUJIAN LONGSHENG BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] These existing technologies mainly use traditional Chinese medicine extracts, chemical drugs, traditional Chinese medicine powder, etc. to make external preparations for treatment. The ingredients mainly act on the blood vessels of the meridian system to improve blood circulation. It only acts on part of the three major systems of blood vessels, nerves, and body fluids in the meridian system. At the same time, due to the natural barrier function of the stratum corneum of the human skin, various active substances enter the skin very limited, and the curative effect is not very ideal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The short transdermal peptide sequence is: Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly.

[0039] The water-soluble curcumin contains the following raw materials: curcumin (95%) 0.5kg, fructooligosaccharides 15kg, wherein curcumin: fructooligosaccharides=1:30.

[0040] A kind of preparation method of water-soluble curcumin, comprises the following steps:

[0041] (1) Add 15kg of fructo-oligosaccharide to 22.5kg of 30°C deionized water in the batching mixing tank and stir until it completely dissolves to form a 40% fructo-oligosaccharide liquid, and the interlayer is cooled to the temperature of the fructo-oligosaccharide solution system with cooling water 18°C;

[0042] (2) be 85% edible alcohol 4kg dissolving with curcumin 0.5kg in addition by volume percentage, be made into the curcumin solution that mass percentage is 11.1%;

[0043] (3) The batching mixing tank opens the agitator, the rotating speed is 210r / min, and slowly the curcumin solution flows into the fruct...

Embodiment 2

[0051] The structure of the transdermal short peptide and the preparation method of water-soluble curcumin are the same as in Example 1.

[0052] A preparation method of the meridian-activating cervical patch is as follows:

[0053] Step 1: Add 0.1 g of carbomer and 50 g of deionized water into the batching tank A, heat to 80°C, keep stirring for 20 minutes, and then stop heating to obtain material A;

[0054] Step 2, add cannabis (CANNABIS SATIVA) leaf extract 0.1g, Evodia rutaecarpa (EVODIARUTAECARPA) fruit extract 0.1g, water-soluble curcumin 0.1g, oat (AVENA SATIVA) coarse powder extract 0.25g, red 0.05g of bisabolol, 0.5g of hydroxyethylurea, 20g of deionized water, heated to 42°C, kept stirring for 20min, then stopped heating to obtain material B;

[0055] Step 3: Turn on the interlayer cooling water in the batching tank of A batching tank and turn on the stirring. After the temperature of the material A in the batching tank drops to 42°C, add the material B in the batc...

Embodiment 3

[0059] The structure of the transdermal short peptide and the preparation method of water-soluble curcumin are the same as in Example 1.

[0060] A preparation method of the meridian-activating cervical patch is as follows:

[0061] Step 1: Add 0.5 g of carbomer and 45 g of deionized water to the batching tank A, heat to 84°C, keep stirring for 20 minutes, and then stop heating to obtain material A;

[0062] Step 2, add 0.6g of cannabis (CANNABIS SATIVA) leaf extract, 0.6g of Evodia Rutaecarpa fruit extract, 0.6g of water-soluble curcumin, 1.0g of oat (AVENA SATIVA) coarse powder extract, red 0.3g of bisabolol, 4.0g of hydroxyethylurea, and 20g of deionized water were heated to 42°C, kept stirring for 20 minutes, and then stopped heating to obtain material B;

[0063] Step 3: Turn on the interlayer cooling water in the batching tank of A batching tank and turn on the stirring. After the temperature of the material A in the batching tank drops to 42°C, add the material B in th...

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PUM

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Abstract

The invention provides a channel dredging and collateral activating cervical vertebra sticking-plaster formula which is characterized by comprising, in weight percent, 0.1-0.6% of falcate dolichos leaf extracts, 0.1-0.6% of medicinal evodia fruit extracts, 0.1-0.6% of water-soluble curcumin, 0.01-0.06% of transdermal short-chain polypeptide TD 1, 0.25-1.0% of oat coarse powder extracts, 0.05-0.30%of bisabolol, 0.10-0.5% of carbopol, 0.1-0.5% of triethanolamine, 0.5-4.0% of hydroxyethylurea and the rest deionized water. The formula has effects on an integrated channel and collateral system ofa human cervical vertebra portion comprising blood vessels, nerves and body fluid and particularly remarkable treatment effects on cervical spondylotic and vertebral artery type cervical spondylopathy.

Description

technical field [0001] The present invention relates to a formula for dredging meridian and activating cervical spine paste and a preparation method thereof, belonging to the technical field of cervical spine paste. Background technique [0002] Cervical spondylosis is clinical common disease, and it can be divided into nerve root type, vertebral artery type, spinal cord type, sympathetic type etc. Clinically, cervical spondylotic radiculopathy combined with vertebral artery type is particularly common, and its common clinical manifestations are mainly neck movement disturbance, neck pain or accompanied by radiating pain and numbness in the upper limbs. It can be aggravated when the neck is flexed and extended or the affected side is rotated, especially when sleeping at night, it is difficult to adjust the height, softness and hardness of the pillow, the upper limbs are heavy, the grip strength is weakened, the holding object sometimes falls, and it may be accompanied by mus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/18A61K47/32A61K38/08A61P19/08A61K36/899A61K31/045A61K31/12
CPCA61K9/7023A61K47/18A61K47/32A61K38/08A61K36/754A61K31/12A61K36/60A61K36/899A61K31/045A61P19/08A61K2300/00Y02P20/54
Inventor 温龙平饶照明林冠雄
Owner FUJIAN LONGSHENG BIOLOGICAL TECH CO LTD
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