Traditional Chinese medicine enema for treating non-alcoholic steatohepatitis as well as preparation method and application method of traditional Chinese medicine enema

A steatohepatitis and non-alcoholic technology, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, drug delivery, etc., can solve problems such as gastrointestinal dysfunction, decreased blood drug concentration, and limited drug dosage

Active Publication Date: 2020-07-07
黑龙江省医院
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although in the prior art, Chinese patents (patent publication numbers CN 105833179A and CN 110339252A) all disclose traditional Chinese medicines for the treatment of nonalcoholic steatohepatitis, most of the existing Chinese medicine compounds for the treatment of nonalcoholic steatohepatitis are oral preparations. Although there is a certain curative effect, due to the gastrointestinal congestion, endotoxin stimulation, intestinal flora imbalance and gastrointestinal dysfu

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine enema for treating non-alcoholic steatohepatitis as well as preparation method and application method of traditional Chinese medicine enema
  • Traditional Chinese medicine enema for treating non-alcoholic steatohepatitis as well as preparation method and application method of traditional Chinese medicine enema

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0028] The traditional Chinese medicine enema composition used in the prevention and treatment of non-alcoholic steatohepatitis in this example is made of the following Chinese medicine raw materials with the following mass ratio: capillary wormwood 20g, red peony root 15g, salvia miltiorrhiza 15g, safflower 10g, peach kernel 10g, chai Hu 20g, Paeoniae Alba 20g, Rhubarb 10g, Scutellaria baicalensis 15g, Astragalus 30g, Poria cocos 15g, Stir-fried Atractylodes macrocephala 15g, Corydalis 10g, Toosendan 10g.

[0029] The specific preparation method is as follows:

[0030] (1) Weigh the crude drug according to the above ratio, put it into a casserole, add clear water to cover the medicine surface, and soak for 20 minutes;

[0031] (2) Boil the crude drug soaked in clear water in a casserole for 10 minutes with strong fire, then decoct with slow fire for 25 minutes, filter to get the decoction, and set aside;

[0032] (3) Add the remaining filter residue filtered in step 2 into c...

specific Embodiment approach 2

[0035] The traditional Chinese medicine enema composition used in the prevention and treatment of non-alcoholic steatohepatitis in this example is made of the following Chinese medicine raw materials with the following mass ratio: capillary root 30g, red peony root 20g, salvia miltiorrhiza 20g, safflower 10g, peach kernel 10g, chai Hu 30g, Baishao 25g, Rhubarb 10g, Scutellaria baicalensis 20g, Astragalus 40g, Poria cocos 20g, fried Atractylodes macrocephala 20g, Corydalis 10g, Toosendan 10g.

[0036] The specific preparation method is as follows:

[0037] (1) Weigh the crude drug according to the above ratio, put it into a casserole, add water to cover the surface of the medicine, and soak for 25 minutes;

[0038] (2) Boil the crude drug soaked in clear water in a casserole for 10 minutes with strong fire, then decoct with slow fire for 30 minutes, filter to get the decoction, and set aside;

[0039] (3) Add the remaining filter residue filtered in step 2 into clear water wit...

specific Embodiment approach 3

[0042] The traditional Chinese medicine enema composition used in the prevention and treatment of non-alcoholic steatohepatitis in this example is made of the following Chinese medicine raw materials with the following mass ratio: capillary root 25g, red peony root 15g, salvia miltiorrhiza 20g, safflower 5g, peach kernel 5g, chai Hu 30g, white peony 20g, rhubarb 5g, baicalin 15g, astragalus 25g, poria cocos 15g, fried Atractylodes macrocephala 15g, corydalis 10g, toosendan 10g.

[0043] The specific preparation method is as follows:

[0044] (1) Weigh the crude drug according to the above ratio, put it into a casserole, add clear water to cover the medicine surface, and soak for 20 minutes;

[0045] (2) Boil the crude drug soaked in clear water in a casserole for 10 minutes with strong fire, then decoct with slow fire for 20 minutes, filter to get the decoction, and set aside;

[0046] (3) Add the remaining filter residue filtered in step 2 into clear water and cover the nood...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a traditional Chinese medicine enema for treating non-alcoholic steatohepatitis as well as a preparation method and application method of the traditional Chinese medicine enema. The traditional Chinese medicine enema consists of the following raw material drugs: herba artemisiae scopariae, radix paeoniae rubra, radix salviae miltiorrhizae, flos carthami, semen persicae, radix bupleuri, radix paeoniae alba, rheum officinale, radix scutellariae, radix astragali, poria cocos, roasted rhizome atractylodis macrocephalae, rhizoma corydalis and fructus toosendan. The drugs aredirectly absorbed through intestinal mucosae by virtue of a retention enema method based on a ''gut-liver axis'' theory, so that damage caused by gastric acid and digestive juice to the drugs is reduced, and the utilization rate of drugs is increased; toxic metabolites and toxins in enteric cavities and on the intestinal mucosae can be directly eliminated, intestinal florae can be regulated, thesituation that toxic substances enter livers through enterohepatic circulation can be avoided, clinical symptoms and signs of patients can be effectively relieved, liver functions and blood lipid parameters of can be reduced, the intestinal florae can be improved, and the non-alcoholic steatohepatitis can be effectively prevented and treated. Besides, the traditional Chinese medicine enema can beindependently used and can be combined with other drugs and treatment methods for use.

Description

technical field [0001] The invention relates to a traditional Chinese medicine enema for treating non-alcoholic steatohepatitis and its preparation method and application method, in particular to a traditional Chinese medicine enema for preventing and treating non-alcoholic steatohepatitis and non-alcoholic liver fibrosis combination agent. Background technique [0002] Nonalcoholic fatty liver disease (NAFLD) is a metabolic stress-induced liver injury closely associated with insulin resistance and genetic susceptibility, including nonalcoholic hepatic steatosis, nonalcoholic steatohepatitis (NASH), cirrhosis and Hepatocellular carcinoma (HCC). With the improvement of living standards and changes in dietary structure, NAFLD has gradually become the chronic liver disease with the highest incidence in my country. NASH is an intermediate stage of simple fatty liver progressing to liver cirrhosis and HCC, and it is difficult to recover on its own. In NASH patients, the liver f...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/736A61K9/00A61P1/16
CPCA61K9/0031A61K36/076A61K36/233A61K36/282A61K36/284A61K36/286A61K36/481A61K36/537A61K36/539A61K36/58A61K36/65A61K36/66A61K36/708A61K36/71A61K36/736A61K2236/331A61K2236/51A61P1/16A61K2300/00
Inventor 张晓星杨川刘延东
Owner 黑龙江省医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap