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A kind of preparation method and application of sugar beet extract

A kind of sugar beet extract, technology of extract

Active Publication Date: 2021-09-14
杭州益瑞医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, allopurinol and febuxostat, a non-purine xanthine oxidase inhibitor, are the main anti-hyperuric acid drugs, but both have many side effects

Method used

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  • A kind of preparation method and application of sugar beet extract
  • A kind of preparation method and application of sugar beet extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A preparation method of sugar beet extract:

[0032] (1) Take 30kg of beets, break them into pieces as appropriate, add 180kg of 90% ethanol to extract 3 times, each time for 1 hour, to obtain the beet extract; add 600kg of water to the remaining beet pulp, decoct for 1 hour, and obtain the beet water extract, and Obtain water extract of beet at 3000 r·min -1 centrifuged at a rotating speed of 10 minutes to obtain the sugar beet water extraction centrifugate;

[0033] (2) Recover the ethanol from the beet extract to obtain the extract, combine the extract with the beet water extraction centrifuge, concentrate to a relative density of 1.05, add 95% ethanol with a weight fraction of 1 times, stir evenly, and precipitate at 20°C for 12 hours ;

[0034] (3) Take the alcohol precipitation supernatant, recover ethanol until there is no alcohol smell, add water with a weight fraction of 1 times, stir well, and let it stand for 3 hours;

[0035] (4) solid-liquid separation i...

Embodiment 2

[0039] A preparation method of sugar beet extract:

[0040] (1) Take 25kg of beet pulp (meal), crush it as appropriate, add 500kg of 30% ethanol to extract twice, 1 hour each time, to obtain the beet extract; add 250kg of water to extract the remaining beet pulp twice, 1 hour each time, To obtain the beet water extract, the beet water extract was heated at 10000 r min -1 Centrifuge at a rotating speed of 1 minute to obtain the sugar beet water extraction centrifugate;

[0041] (2) Recover the ethanol from the beet extract to obtain the extract, combine the extract with the beet water extraction centrifuge, concentrate to a relative density of 1.15, add 95% ethanol twice the weight fraction, stir evenly, and precipitate at 10°C for 24 hours ;

[0042] (3) Take the alcohol-precipitated supernatant, recover the ethanol until there is no alcohol smell, add water with a weight fraction 3 times, stir well, and let stand for 36 hours;

[0043] (4) Plate and frame filtration, the s...

Embodiment 3

[0047] A preparation method of sugar beet extract:

[0048] (1) Take 50kg of beets, crush them as appropriate, add 500kg of 60% ethanol to extract twice, each time for 1.5 hours, to obtain the beet extract; add 250kg of water to the beet pulp, decoct for 1 hour, to obtain the beet water extract, and the beet water Extraction at 20000 r·min -1 centrifuged at a rotating speed of 10 minutes to obtain the sugar beet water extraction centrifugate;

[0049] (2) Recover the ethanol from the beet extract to obtain the extract, combine the extract with the beet water extraction centrifuge, concentrate to a relative density of 1.30, add 95% ethanol with a weight fraction 5 times, stir evenly, and precipitate at 4°C for 48 hours ;

[0050] (3) Take the alcohol precipitation supernatant, recover ethanol until there is no alcohol smell, add water with a weight fraction of 5 times, stir well, and let stand for 48 hours;

[0051] (4) Plate and frame filtration, the solution is filtered th...

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Abstract

The invention discloses a preparation method and application of a sugar beet extract. The preparation method is as follows: first extract the sugar beet with ethanol-water for 1-3 times, and then extract with water, add ethanol precipitation to the concentrated extract, recover ethanol, water-soluble, solid liquid separation, clarification by microfiltration, membrane concentration, and drying to obtain sugar beet extract. The sugar beet extract of the invention retains the active components of the sugar beet to the greatest extent, and at the same time greatly reduces the content of sucrose, and can be applied to medicines for regulating blood fat or uric acid.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a preparation method and application of a sugar beet extract. Background technique [0002] Beet (Beta vulgaris L.) is a biennial herb belonging to the Chenopodiaceae family and belongs to the genus Beta. Beet planting plays an important role in the national economy and is the main sugar crop in northern my country, with an annual output of 12 million tons. In addition to containing more sucrose, beets are also rich in dietary fiber, betaine, raffinose, betalain, carotene, saponins and other substances, and are currently mainly used in the production of sucrose and dietary fiber. Uric acid is the final product of human purine and nucleic acid catabolism. The sources of uric acid include endogenous uric acid and exogenous uric acid. is the intake of purine-rich foods. In recent years, with the improvement of people's living standards, a large number of epidemiological studies...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P3/06A61P19/06A23L33/105A21D2/36A21D13/80A23G3/48A23L2/40
CPCA21D2/36A23G3/48A23L2/40A23V2002/00A61K36/185A61K2236/333A61K2236/39A61K2236/51A61K2236/53A23L33/105A21D13/80A61P3/06A61P19/06A23V2250/21A23V2200/3262A23V2200/30
Inventor 田景奎李守信宫明华吴知盼朱玮
Owner 杭州益瑞医药科技有限公司
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