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Application of composition in prevention or treatment of diseases caused by escherichia coli of broiler chickens

A technology of composition and use, applied in the field of medicine, can solve problems to be studied, achieve good treatment, increase lipase activity, and increase the effect of quantity

Active Publication Date: 2020-09-08
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, Chinese herbal medicines suitable for the prevention or treatment of diseases caused by E. coli infection are still to be studied

Method used

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  • Application of composition in prevention or treatment of diseases caused by escherichia coli of broiler chickens
  • Application of composition in prevention or treatment of diseases caused by escherichia coli of broiler chickens
  • Application of composition in prevention or treatment of diseases caused by escherichia coli of broiler chickens

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0033] Determination of the diameter of the inhibition zone

[0034] The diameter of the inhibition zone of the composition against Escherichia coli O78 was measured by a plate agar punching method. Take 0.1mL concentration as 10 8 Place the CFU / mL bacterial solution on the prepared sterile MacConkey culture plate, spread evenly, stop coating the plate when the spreader and the plate have a certain viscosity, and punch holes on the plate with a puncher with a diameter of 6 mm , fill the well with the composition solution and physiological saline with a concentration of 1 g / mL. Place the plate upright in a constant temperature incubator at 37°C, take out the plate after 24 hours of incubation, and measure the diameter of the inhibition zone with a vernier caliper.

[0035] Determination of minimum inhibitory concentration

[0036]The minimum inhibitory concentration of the composition against avian pathogenic Escherichia coli O78 was determined by the test tube double diluti...

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PUM

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Abstract

The invention provides a composition and application thereof in preparation of medicines. The composition comprises 12-18 parts by weight of scutellaria baicalensis, 8-12 parts by weight of cortex phellodendri, 2-8 parts by weight of dahurian patrinia herb, 2-8 parts by weight of hairyvein agrimony, 2-8 parts by weight of forsythia suspense, 2-8 parts by weight of licorice, and 2-8 parts by weightof sanguisorba officinalis. The composition disclosed by the invention can effectively prevent or treat diseases caused by escherichia coli infection of an organism, and has theoretical research andclinical application values.

Description

technical field [0001] The present invention relates to the field of medicine. Specifically, the present invention relates to the application of the composition in the prevention or treatment of diseases caused by Escherichia coli in broilers. Background technique [0002] After avian pathogenic Escherichia coli invades the body, it will cause acute colibacillosis. Broiler colibacillosis is an explosive disease that often occurs during the breeding process. The disease initially manifests as sepsis, followed by sudden death or inflammatory lesions in multiple important organs of the body, such as inflammatory lesions in the liver, heart, air sac, etc. , is a disease with high morbidity and mortality that imposes a severe economic burden on poultry producers worldwide. Although the use of antibiotics and chemical antibacterial drugs can effectively alleviate the damage of pathogenic microorganisms to the body, the residues of antibiotics and the emergence of bacterial resis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/84A61P31/04A61P37/04
CPCA61K36/484A61K36/539A61K36/634A61K36/73A61K36/739A61K36/756A61K36/84A61P31/04A61P37/04A61K2300/00
Inventor 杨鹰武振龙王梦梦
Owner CHINA AGRI UNIV
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