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Device for collecting intestinal fluid

An intestinal juice and gastric juice-resistant technology, which can be used in applications, inoculation and ovulation diagnosis, medical science, etc., and can solve problems such as restricting the observation of microbiota

Active Publication Date: 2020-09-11
UNIV GRENOBLE ALPES +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently, most analyzes are performed on feces, thus limiting the possibility to observe the microbiota

Method used

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  • Device for collecting intestinal fluid
  • Device for collecting intestinal fluid
  • Device for collecting intestinal fluid

Examples

Experimental program
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Effect test

no. 2 example

[0065] According to a second embodiment, the mechanism for closing the opening 3 of the collecting device may comprise:

[0066] - a valve 4 that is not affected by intestinal fluids, the valve is inserted between the outer shell 1 and the inner material 2 and is arranged below the hole 3;

[0067] - a film 5 or particles 6 with an average diameter between 0.10 mm and 2 mm, said film 5 or said particles 6 comprising a polymer suitable for dissolving in intestinal fluid at a temperature of 37° C., said film 5 or said particles 6 The particles 6 are arranged between the valve 4 and the housing 1,

[0068] Therein the film 5 or the particles 6 together with the shell 1 form a channel so that the intestinal fluid is suitable for passing through it and reaching the inner material 2 .

[0069] More specifically, according to figure 2 In a first alternative to the second embodiment shown, the mechanism for closing the opening 3 of the device comprises:

[0070] - a valve 4 that i...

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Abstract

The application relates to a device for collecting an intestinal fluid sample, comprising: an inner polymeric material: - having an open cellular structure which is at least partially compressed, having a volume V, and capable of swelling to a volume greater than or equal to 1.1 * V, by absorbing intestinal fluid, the inner material being wrapped in an envelope made of elastic polymer and impervious to digestive fluid, the envelope comprising at least one opening for admitting the intestinal fluid into the internal material, a gastro-resistant material capable of dissolving in the intestinal fluid at 37 DEG C being arranged above each opening; and at least one mechanism for closing the opening(s).

Description

technical field [0001] The present invention relates to a device for collecting samples of intestinal fluid from humans or animals, in particular for research and diagnostic purposes. Background technique [0002] Knowledge of the digestive system and its microbiota is considered an important topic for human or animal health. In terms of disease diagnosis, it is crucial to be able to qualitatively and quantitatively characterize the microbiota contained in different parts of the digestive system, especially the gut. [0003] Currently, most analyzes are performed on stool, thus limiting the possibility to observe the microbiota. Despite the continuous improvement and low cost of current analytical methods, there is a need for an automated device with no negative health effects that is simple and inexpensive for sampling microbiota from intestinal fluid. [0004] Devices for collecting intestinal fluids are known, in particular from applications DE19801573 and US5971942, wh...

Claims

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Application Information

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IPC IPC(8): A61B10/00
CPCA61B10/0045A61B2010/0061
Inventor 雅克·路图菲利普·辛奎因唐纳德·基思·马丁托马斯·索兰佐让-皮埃尔·阿尔卡拉斯让-马克·奎特
Owner UNIV GRENOBLE ALPES