Flexible nano-liposome acne-removing lotion with pH targeting and preparation method thereof

Abstract

The invention discloses a flexible nano-liposome acne-removing emulsion with pH targeting and a preparation method thereof. The prescription comprises a pH-targeted flexible nano-liposome coated withactive ingredients, glycosyl trehalose, melaleuca alternifolia leaf oil, resina liquidambaris, almond oil, water-soluble laurocapram and the like, wherein the active ingredients are extracts of iris ensata, aster tataricus, bock greenbrier rhizome, cucubalus roots, pontederia cordata and apocynum venetum. According to the acne-removing lotion prepared by the invention, the deformability of the flexible nano-liposome is utilized, so that the active ingredients go deep into the epidermal layer and the corium layer, growth of propionibacterium acnes and excessive secretion of grease in the skin are inhibited, inflammation is relieved and diminished, and regeneration of scar tissues is promoted.

Description

technical field [0001] The invention belongs to the technical field of external acne-removing skin care products, and in particular relates to a flexible nano-liposome acne-removing milk with pH targeting and a preparation method thereof. Background technique [0002] There are currently two main types of topical products for acne: Topical medications. Common drugs for acne treatment include topical retinoic acid, hormones, and antibiotics, but they all have certain problems, such as: traditional topical retinoic acid and benzoyl peroxide preparations have poor stability and local irritation is common 1. The problem of poor drug resistance to antibiotics is becoming more and more serious. Hormone drugs can only play a pseudo-acne effect, making the skin dependent and long-term use will seriously damage the skin, and even cause hormone-dependent dermatitis; Acne skin care products. Existing anti-acne skin care products have problems such as poor skin penetration rate, po...

AI Technical Summary

Problems solved by technology

Common drugs for acne treatment include topical retinoic acid, hormones, and antibiotics, but they all have certain problems, such as: traditional topical retinoic acid and benzoyl peroxide preparations have poor stability and local irritation is common 1. The problem of poor drug resistance to antibiotics is becoming more and more serious. Hormone drugs can only play a pseudo-acne effect, making the skin dependent and long-term use will seriously damage the skin, and even cause hormone-dependent dermatitis; acne skin care products

Existing anti-acne skin care products have problems such as poor skin penetration, poor targeting, and many side effects, which can easily cause damage to normal skin

The use of skin penetration enhancers (such as: methyl sulfoxides) can increase the skin penetration rate, but at the same time it may also become a source of irritation and allergies to the skin, and even consumers continue to use sealants (such as: fatty alcohols) ) hydrating and anti-acne products, the pores are further clogged, resulting in more severe acne

[0003] The active ingredients in traditional skin care products are complex, many of which are macromolecules, which can only stay on the skin surface or epidermis, and are difficult to enter the dermis, and the skin penetration rate is extremely low, only 5%.

Common acne inflammations (such as pimples, cysts, and lumps) erode into the dermis, and ingredients with low transmittance are difficult to reach the inflammation site, and the treatment and skin care effects are often poor