Full-automatic mass spectrum pretreatment system

A fully automatic mass spectrometry technology, applied in the field of fully automatic mass spectrometry pretreatment system, can solve the problems of long processing time, complicated operation, difficult to achieve high throughput, etc., and achieve the effect of strong automation ability

Active Publication Date: 2020-10-02
苏州创新通用色谱仪器有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the shortcomings of long sample pretreatment time, complicated operation, difficulty in achieving high throughput, and automation, re

Method used

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  • Full-automatic mass spectrum pretreatment system
  • Full-automatic mass spectrum pretreatment system
  • Full-automatic mass spectrum pretreatment system

Examples

Experimental program
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Embodiment Construction

[0052] refer to Figure 1-3As shown, a fully automatic mass spectrometry pretreatment system includes a pipetting module, a centrifugal module, a placement module, a working module, and an acquisition module. The pipetting module is connected to the centrifugal module in one direction, and the centrifugal module is connected to the placement module in one direction. Two-way connection with the working module, two-way connection between the placement module and the pipetting module, one-way connection between the working module and the acquisition module;

[0053] The pipetting module is used to add samples and protein agents to the centrifuge tube and move the centrifuge tube to the centrifuge;

[0054] The centrifuge module is used to centrifuge the sample in the centrifuge tube;

[0055] The placement module is used to move the centrifuged sample placed in the centrifuge tube to the centrifuge tube rack together with the centrifuge tube;

[0056] The working module is used...

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Abstract

The invention discloses a full-automatic mass spectrum pretreatment system, which is formed by combining a pipetting module, a centrifugation module, a placing module, a working module, a collecting module and the like, and is controlled by computer software to carry out coordination work so as to realize unattended sample pretreatment and sample introduction. The pipetting module, the centrifugation module, the placing module, the working module, the collecting module and the like share one set of x-axis guide rail and respectively use an independent y-axis guide rail and an independent z-axis guide rail, so that the modules do not interfere with each other during operation. Automatic liquid adding and pipetting equipment is jointly controlled by a four-way joint and a plurality of electromagnetic valves, and operations such as liquid suction by a needle head and liquid suction behind the needle can be performed. According to an online solid-phase extraction system, the connection anddisconnection of a solid-phase extraction column and a liquid-phase system are controlled by a six-way valve, so that the equipment can accurately and stably work and operate without personnel participation, and the system disclosed by the invention has extremely strong automation capability.

Description

technical field [0001] The invention belongs to the field of mass spectrometry processing systems, in particular to a fully automatic mass spectrometry preprocessing system. Background technique [0002] When mass spectrometry determines the molecular weight of a known target compound, if the impurity content is high or the concentration of the analyte is low, the abundance and resolution of the peak corresponding to the target compound will be low. In this case, the interference of impurities will be particularly obvious, causing this samples cannot be accurately measured. [0003] In the analysis and detection of complex samples, the pretreatment technology of samples is very important. In recent years, a variety of sample pretreatment technologies have developed rapidly and are suitable for pretreatment of various types of samples. Techniques such as solid-phase extraction, solid-phase microextraction, magnetic extraction, ultrasonic-assisted extraction, ultrafiltration...

Claims

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Application Information

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IPC IPC(8): G01N30/02G01N30/06G01N30/20G01N30/72
CPCG01N30/02G01N30/06G01N30/20G01N30/72G01N2030/062G01N2030/201
Inventor 张业平刘继宇
Owner 苏州创新通用色谱仪器有限公司
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