Anti-cea antibody and application thereof, cell capable of secreting anti-cea antibody and preparation method thereof

An antibody and cell technology, applied in genetically modified cells, biochemical equipment and methods, cells modified by introducing foreign genetic material, etc., can solve the problem of poor specificity of anti-CEA antibodies
CN111748039BActive Publication Date: 2022-06-03SHENZHEN YHLO BIOTECH +2
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN YHLO BIOTECH
Publication Date
2022-06-03

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Abstract

The invention relates to an anti-CEA antibody and its application, a cell capable of secreting an anti-CEA antibody and a preparation method thereof. The anti-CEA antibody includes a first structural domain and a second structural domain. The first structural domain includes a first light chain variable region and a first heavy chain variable region. The amino acid sequence of the first light chain variable region is as SEQ ID No. 1, the amino acid sequence of the first heavy chain variable region is shown in SEQ ID No.2; the second structural domain includes the second light chain variable region and the second heavy chain variable region, and the second light chain variable region The amino acid sequence of the region is shown in SEQ ID No.3, and the amino acid sequence of the second heavy chain variable region is shown in SEQ ID No.4. The specificity of the above-mentioned anti-CEA antibody is better.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to an anti-CEA antibody and its application, a cell capable of secreting an anti-CEA antibody and a preparation method thereof. Background technique

[0002] Cancer, also known as malignant tumor, can proliferate indefinitely and consume a large amount of nutrients in the patient's body. Cancer cells can also release a variety of toxins, causing a series of pathological symptoms in the human body. Cancer cells can also be transferred to the whole body. It grows and reproduces everywhere. The occurrence of cancer has brought great troubles to the lives of many patients, and even directly threatens the life and health of the body. For the treatment of cancer, the earlier it is found and treated, the better the treatment effect will be.

[0003] Traditional tumor screening methods are mainly X-ray photography or detection of serum tumor markers, etc., but the irreversible damage caused b...

Claims

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