Single-point dixon method for fat-water separation in chemical exchange saturation transfer magnetic resonance imaging

一种磁共振成像、医学成像系统的技术，应用在使用核磁共振图像系统进行测量、磁共振测量、磁场的大小/方向等方向，能够解决水信号影响等问题

Active Publication Date: 2020-10-27
KONINKLJIJKE PHILIPS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This is due to the fact that saturation pulses may also have an effect on the water signal

Method used

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  • Single-point dixon method for fat-water separation in chemical exchange saturation transfer magnetic resonance imaging
  • Single-point dixon method for fat-water separation in chemical exchange saturation transfer magnetic resonance imaging
  • Single-point dixon method for fat-water separation in chemical exchange saturation transfer magnetic resonance imaging

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Embodiment Construction

[0149] Like numbered elements in these figures are equivalent elements or perform the same function. Elements that have been discussed previously will not necessarily be discussed in subsequent figures if the function is equivalent.

[0150] figure 1 An example of a medical imaging system 100 is shown. The medical imaging system 100 includes a computer 102 . The computer includes a processor 104 shown optionally connected to a hardware interface 106 . Processor 104 is also optionally shown connected to user interface 108 . Processor 104 is shown connected to memory 110 . Memory 110 may be any combination of memories accessible to processor 104 . This can include things such as main memory, cache memory, and also non-volatile memory such as flash RAM, hard drives or other storage devices. In some examples, memory 110 may be considered a non-transitory computer-readable medium.

[0151] The hardware interface 106 may, for example, be used to control other components of th...

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Abstract

The invention provides for a medical imaging system (100, 300). The medical imaging system comprises a processor (104). Execution of machine executable instructions (120) causes the processor to: receive (200) magnetic resonance imaging data (122) comprising a Z-spectrum acquisition (124) for a set of saturation frequency offsets (126) and at least one reference saturation frequency offset (128);reconstruct (202) saturation frequency offset complex image data (130); reconstruct (204) a B0 map (132), a water image (134), and a fat image (136) according to a Dixon-type magnetic resonance imaging protocol; calculate (206) a water phase angle (138) using the water image and / or the fat image; calculate (208) rotated complex image data (140) by rotating the phase of the saturation frequency offset complex image data such that the complex water signal is aligned with a real axis for each voxel; perform (210) a B0 correction by calculating shifted complex image data (142); calculate (212) afrequency dependent phase angle (144) descriptive of a phase angle between the complex water signal and the complex fat signal for each of the set of saturation frequency offsets using a fat signal model comprising at least two fat species; calculate (214) a residual fat component correction factor (150) by projecting the complex fat signal onto the real axis for each of the set of saturation frequency offsets; and calculate (216) corrected water Z-spectrum image data (152) by subtracting the residual fat component correction factor for each of the set of saturation frequency offsets from thereal component of the shifted complex image data.

Description

technical field [0001] The present invention relates to magnetic resonance imaging, in particular it relates to CEST or APT magnetic resonance imaging. Background technique [0002] Magnetic resonance imaging (MRI) scanners rely on large static magnetic fields (B 0 ) in order to align the nuclear spins of the atoms as part of the process used to generate the image in the patient's body. These images can reflect various quantities or properties of objects. For example, the density of hydrogen protons can be spatially measured and resolved. Often, however, the compound or metabolite is so dilute that it is practically impossible to image it directly. [0003] Therefore, techniques such as chemical exchange saturation transfer (CEST) MRI have been developed. In CEST imaging, the presence of dilute metabolites with exchangeable protons is measured. Protons of metabolites that can be studied using CEST are able to exchange places with protons from water. Saturation pulses c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01R33/48G01R33/56A61B5/055G01R33/24
CPCA61B5/055G01R33/243G01R33/4828G01R33/5605G01R33/583
Inventor J·库普H·埃格斯
Owner KONINKLJIJKE PHILIPS NV
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