Extra cellular matrix biological material generated by embryonic stem cells as well as preparation method and application of extra cellular matrix biological material
A technology of embryonic stem cells and biological materials, which is applied to the field of extracellular matrix biological materials produced by embryonic stem cells and their preparation, can solve the problems of unstable source of donated bone marrow, individual differences of bone marrow cells, and high cost, and achieves the enhancement of biological antioxidant function. Effect
Inactive Publication Date: 2020-11-10
宏俊生物科技有限公司
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Problems solved by technology
[0003] There are many shortcomings in the existing technology, including: for example, the team at the University of Texas used bone marrow cells from young adults to produce ECM, and the source of donated bone marrow is unstable and the cost is high; there is damage to the donor; there are individual differences in bone marrow cells, which affect the actual ECM. impact unknown
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[0018] The present invention will be further described in detail in conjunction with the following specific embodiments and accompanying drawings. The process, conditions, experimental methods, etc. for implementing the present invention, except for the content specifically mentioned below, are common knowledge and common knowledge in this field, and the present invention has no special limitation content.
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The invention discloses a biological material consisting of extra cellular matrix proteins generated by embryonic stem cells. The biological material consists of the extra cellular matrix proteins generated by the embryonic stem cells. The invention further discloses a preparation method of the biological material. The invention also discloses an application of the biological material. The biological material can be applied to prevention of stem cell oxidative stress damage, cell transplantation treatment, regenerative medicine and the like. The biological material has a wide application prospect.
Description
technical field [0001] The invention relates to the technical field of biomedicine, in particular to an extracellular matrix biological material produced by embryonic stem cells and its preparation method and application. Background technique [0002] Mesenchymal stem cells (mesenchymal stem cells, MSCs) are very sensitive to the culture environment and conditions because of their active proliferation and differentiation capabilities, and are often stimulated by certain factors during in vitro expansion and passage to differentiate, Transformation into other adult cells and loss of "stemness" (Stemness); with the increase of subculture generations, mesenchymal stem cells will also undergo certain changes in gene or protein expression, showing "aging" phenomenon, these instability This greatly limits the clinical application value of mesenchymal stem cells. In addition, mesenchymal cells derived from autologous adipose tissue are affected by many factors such as the age, hea...
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Login to View More IPC IPC(8): C12N5/0735C12N5/0775
CPCC12N5/0606C12N5/0667C12N2533/90
Inventor 朱晗
Owner 宏俊生物科技有限公司
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