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Traditional Chinese medicine composition for treating malignant pleural effusion

A malignant pleural effusion and composition technology, applied in the direction of drug combination, medical raw materials derived from birds, medical raw materials derived from fungi, etc., can solve the problems of high recurrence rate of patients, improve the quality of life, prolong survival time, Effects of slowing the formation of malignant pleural effusions

Active Publication Date: 2020-11-17
陕西省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Domestic doctors have made a lot of active explorations based on clinical practice, but most clinical studies have shown that the recurrence rate of patients in the short term is still high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1 Chinese medicine composition and taking method

[0031] Take rehmannia glutinosa 60g, angelica 10g, fried yam 20g, dogwood 20g, poria cocos 20g, polyporus 20g, Alisma 20g, Tinglizi 20g, sea jinsha 20g, gallinacea 10g, amomum 10g. Put the above traditional Chinese medicine into a casserole, add cold drinking water, soak for 20-30 minutes, add water to submerge the medicine, put the medicine casserole on the stove and cook over medium heat. Boil for half an hour, and take 150-200mL of the medicinal solution: Then, add an appropriate amount of warm water, and cook for half an hour, and take 150-200mL of the medicinal solution. Mix the two decoctions and take it in the morning and evening.

Embodiment 2

[0032] Malignant pleural effusion caused by colon cancer treated by embodiment 2 traditional Chinese medicine composition

[0033] Patient Gao, male, 71 years old. In July 2017, the patient developed cough, sputum, and shortness of breath without any obvious cause, so he went to the 323rd Hospital of the Chinese People’s Liberation Army. After symptomatic treatment, the symptoms improved. On August 2017, he was hospitalized again due to swelling of both lower limbs and shortness of breath. The blood test showed: anemia Elevated tumor markers; Chest X-ray showed a large amount of pleural effusion; during hospitalization, the patient had repeated high fever and obvious shortness of breath, and was given thoracentesis of about 1200mL and other symptomatic treatment. PET-CT showed that the intestinal wall of the upper ascending colon was thickened circularly or heart-shaped, the thickest part was about 1.7 cm, the length of the lesion was about 3.6 cm, and the metabolism was incre...

Embodiment 3

[0034] Embodiment 3 Chinese medicine composition treats malignant pleural effusion caused by lung cancer

[0035] Kou, male, 58 years old. On April 16, 2020, he came to our hospital for outpatient treatment with a diagnosis of lung cancer for 3.5 months. The patient was diagnosed with a malignant lung tumor (left lung adenocarcinoma T4N3M1a) in December 2019, with lymph node metastasis in the lung, pleura, and mediastinum, and a large amount of pleural effusion on the left side. He had pumped pleural effusion 5 times successively, and used endostar, cisplatin, etc. to perfuse the pleural cavity, but the effect was not good. Hospital B-ultrasound on April 16, 2020: a large amount of pleural effusion on the left side (a large amount, partially wrapped), and a small amount of pleural effusion on the right side. Then begin to take treatment by the decocting method of embodiment 1 with Chinese medicine composition of the present invention, patient's symptom, quality of life all h...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating malignant pleural effusion, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicinecomposition is prepared from the following traditional Chinese medicines of, in parts by weight, 4-12 parts of prepared rehmannia root, 1-3 parts of angelica sinensis, 1-3 parts of fried Chinese yam,1-3 parts of dogwood, 1-3 parts of poria cocos, 1-3 parts of polyporus umbellatus, 1-3 parts of rhizoma alismatis, 1-3 parts of semen lepidii, 1-3 parts of spora lygodii, 1 part of endothelium corneumgigeriae galli and 1 part of fructus amomi. The traditional Chinese medicine composition has the effects of tonifying liver and kidney, inducing diuresis and resolving dampness, and can be used for effectively slowing down the generation of malignant pleural effusion, so that the living quality of patients is improved, and the survival time is prolonged.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating malignant pleural effusion. Background technique [0002] Malignant pleural effusion is the most common late complication of primary pleural tumors or tumor metastasis to the pleura, and is more common in lung cancer and breast cancer. Malignant pleural effusion has clinical characteristics such as rapid growth and bloody majority, which can cause symptoms such as chest tightness, shortness of breath, and dyspnea, seriously affecting the quality of life of patients, and once it occurs, the prognosis is poor. The principle of treatment of malignant pleural effusion is mainly to relieve symptoms, improve quality of life and prolong survival time. Therefore, most of them are palliative and symptomatic treatment. Despite advances in treatment options, the prognosis remains poor, with a median survival of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P35/00A61K35/57
CPCA61K36/804A61K36/232A61K36/8945A61K36/40A61K36/076A61K36/07A61K36/884A61K36/31A61K36/12A61K35/57A61K36/9064A61P35/00A61K2300/00
Inventor 杨晨光孙婧康超缑娇王莉娟刘楠郝梅梅李琳婵许鹏陈捷杨宝钢郭奕飞
Owner 陕西省中医医院
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