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Traditional Chinese medicine volatile oil composition, preparation thereof, and preparing method and application of preparation

A technology of traditional Chinese medicine preparation and volatile oil, applied in the directions of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of slow onset of action, inability of drug effect to reach the hospital, complicated decoction of decoction, etc., achieving good effect and avoiding other adverse effects. Response, the effect of good application prospects

Inactive Publication Date: 2021-02-05
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This medicament can treat pharyngitis, but after taking the medicine, it needs to be absorbed through the gastrointestinal tract, metabolized by the liver and kidney, and the onset mode is relatively slow, and there is a complicated situation of decoction and decoction; as Chinese patent application CN109731078A discloses a Chinese medicine for treating chronic pharyngitis Patch and preparation method thereof, the raw materials of which are A side: 10-30 parts of Chuan Fritillaria, 5-15 parts of Trichosanthes trichosanthes, 10-30 parts of Lily; B side: 10-30 parts of Poria cocos, 5-15 parts of orange red, 5-15 parts of bellflower, 10-30 parts of licorice, 30-50 parts of raw rehmannia, 30-50 parts of Ophiopogon japonicus, 10-30 parts of pinellia, 10-30 parts of ginseng, 10-30 parts of japonica rice
This medicament can treat pharyngitis, but its administration method is external application, through the way of percutaneous absorption, the drug effect cannot reach the sick place directly.

Method used

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  • Traditional Chinese medicine volatile oil composition, preparation thereof, and preparing method and application of preparation
  • Traditional Chinese medicine volatile oil composition, preparation thereof, and preparing method and application of preparation
  • Traditional Chinese medicine volatile oil composition, preparation thereof, and preparing method and application of preparation

Examples

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Effect test

preparation example Construction

[0049] The puffball volatile oil, peppermint volatile oil, scrophulariaceae volatile oil, bellflower volatile oil used in the following examples can be purchased from the market, or prepared by the following methods:

[0050] 1. Preparation of puffball volatile oil: take 1kg puffball and microwave vacuum drying treatment, grind it through a 30-mesh sieve, put it into a supercritical extraction kettle, extraction pressure 30MPa, temperature 50°C, flow rate 300L h -1 , dynamic extraction for 120min to obtain puffball volatile oil.

[0051] 2. Preparation of peppermint volatile oil: Take 1kg of dried peppermint and grind it, grind it through a 30-mesh sieve, put it into a supercritical extraction kettle, extract it at a pressure of 6MPa, a temperature of 50°C, and a flow rate of 300L h -1 , and dynamically extracted for 90 minutes to obtain peppermint volatile oil.

[0052] 3. Preparation of volatile oil from Scrophulariaceae: Cut 1kg Scrophulariaceae into a microwave vacuum dry...

Embodiment 1

[0056] Embodiment 1: Preparation of oral aerosol

[0057] Mix and dissolve 20 parts of puffball volatile oil, 20 parts of scrophulariaceae volatile oil, 15 parts of bellflower volatile oil, 15 parts of peppermint volatile oil, 10 parts of licorice volatile oil and 3 parts of borneol, add an appropriate amount of vegetable glycerin as an emulsifier, and add an appropriate amount of sweet orange essence to adjust the taste. Mix evenly, add to the atomizer, that is.

Embodiment 2

[0058] Embodiment 2: preparation nose smelling agent

[0059] Mix and dissolve 20 parts of puffball volatile oil, 15 parts of scrophulariaceae volatile oil, 15 parts of bellflower volatile oil, 15 parts of peppermint volatile oil, 6 parts of licorice volatile oil and 2 parts of borneol, add cotton core to the mixture and soak for 48 hours, take out the cotton core and put it in ABS injection molding pipe, that is, available.

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Abstract

The present invention provides a traditional Chinese medicine volatile oil composition, a preparation thereof, a preparing method and application of the preparation. The traditional Chinese medicine volatile oil composition is prepared from the components in parts by weight: 1-35 parts of puffball volatile oil, 1-30 parts of peppermint volatile oil, 1-35 parts of radix scrophulariae volatile oil,1-30 parts of platycodon grandiflorum volatile oil, 1-15 parts of licorice volatile oil and 1-5 parts of borneol. The traditional Chinese medicine volatile oil composition is reasonably matched according to the assistant and guide of traditional Chinese medicines, the number of the medicines is small, all the components have a synergistic effect and jointly achieve the effects of clearing away heat and toxic materials and relieving sore throat and pain, and the preparation prepared from the traditional Chinese medicine volatile oil composition serving as an effective component or an active component can be directly administrated from the respiratory tract and directly reach a disease site and is simple, convenient and rapid to take effect. Clinical symptoms such as throat itching, scorching heat, foreign body sensation in throat, pharyngalgia, dry throat, dry cough, nausea when brushing teeth in the morning and speaking too much and the like are effectively relieved in a short time, and the traditional Chinese medicine volatile oil composition is used for preparing a medicine for treating pharyngitis.

Description

technical field [0001] The present invention relates to the field of traditional Chinese medicine, and more specifically, relates to a Chinese medicine volatile oil composition capable of treating pharyngitis, an active ingredient or a Chinese medicine preparation whose active ingredient is the Chinese medicine volatile oil composition, a preparation method of the Chinese medicine preparation, and the Chinese medicine volatile oil composition Application in preparation of medicine for treating pharyngitis. Background technique [0002] Pharyngitis is a general term for pharyngeal mucosa, submucosal and lymphoid tissue inflammation caused by bacterial infection, viral infection, environmental factors, etc. It is a non-specific inflammation of the human pharynx. According to the course of disease, pharyngitis is divided into acute pharyngitis and chronic pharyngitis more. Acute pharyngitis is one of the common upper respiratory tract infectious diseases in adults and children...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61K9/12A61K9/00A61P11/04A61P31/20A61K31/045
CPCA61K9/0014A61K9/0043A61K9/006A61K9/12A61K31/045A61K36/07A61K36/346A61K36/484A61K36/534A61K36/808A61P11/04A61P31/20A61K2300/00
Inventor 郑彩杏周小青刘继平李金霞刁承林
Owner HUNAN UNIV OF CHINESE MEDICINE
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