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Nanofiber mask containing lipidosome and preparation method of nanofiber mask

A technology of nanofibers and nanofiber layers, which is applied in the field of cosmetic formulations, can solve the problems of non-woven fabrics with large fiber diameters, easy friction with the skin, and few contact points, achieving slow release of active ingredients, improved utilization, and good application properties Effect

Active Publication Date: 2021-03-09
JIANGSU JICUI ADVANCED POLYMER MATERIAL RES INST CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Sheet masks are usually made of non-woven fabrics. Although most non-woven fabrics can absorb essence and stick to the skin, there are still the following problems: (1) The diameter of non-woven fabric fibers is large, which is easy to rub against the skin, making it comfortable to use (2) There are few contact points with the skin per unit area, which is not conducive to the penetration of the essence into the skin
(3) Traditional facial mask essences need to add high doses of preservatives because they contain anti-oxidant active ingredients and a lot of water
However, there are still problems that the active ingredients need to be dispersed in the spinning stock solution, which is prone to aggregation, resulting in clogged spraying and uneven fiber size, and the active ingredients are easily oxidized and lose their efficacy during the preparation process, which cannot improve the skin condition. the role of

Method used

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  • Nanofiber mask containing lipidosome and preparation method of nanofiber mask
  • Nanofiber mask containing lipidosome and preparation method of nanofiber mask
  • Nanofiber mask containing lipidosome and preparation method of nanofiber mask

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] 1) Add 0.2g chitosan to 100ml 1%wt aqueous acetic acid solution, stir and dissolve at 40°C. Adjust the pH value of the solution to 6.0 with 0.1M sodium hydroxide solution to obtain solution A.

[0039] 2) Mix solution A with 105mM potassium phosphate buffer solution at a ratio of 1:9 to obtain solution B.

[0040] 3) Add 2g of ferulic acid to 200ml of solution B, stir well to obtain solution C.

[0041] 4) Add 5 mg of horseradish peroxidase to solution C, add 0.5 ml of 10% volume fraction hydrogen peroxide solution every 3 minutes, stop the reaction after 90 minutes, and obtain solution D. The grafting reaction at room temperature was as figure 1 shown.

[0042] 5) Separate the solution D with a centrifuge at a speed of 5000r / min for 15 minutes, and the solution is separated into layers. The precipitated reaction product was collected, dissolved in 1% acetic acid solution with a certain mass fraction, and stored at room temperature until use.

[0043] 6) Dissolve s...

Embodiment 2

[0047] Except that in step 8, the concentration of the acetic acid solution of ferulic acid-grafted chitosan was adjusted to 0.2 mg / ml, the others were the same as in Example 1.

Embodiment 3

[0049] Except that in step 8, the concentration of the acetic acid solution of ferulic acid-grafted chitosan was adjusted to 0.3 mg / ml, the others were the same as in Example 1.

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Abstract

The invention relates to a nanofiber mask containing a lipidosome and a preparation method of the nanofiber mask, and belongs to the field of cosmetic formulas. Nanofiber is used as a mask material, so that the use comfort is improved, and the absorption of essence by the skin is improved. The lipidosome is modified by ferulic acid grafted chitosan, and a layer of protective film is formed on thesurface of the lipidosome through the combination of electrostatic interaction and the lipidosome with negative electricity, so that the stability and the size uniformity of a lipidosome system are improved. Due to the introduction of the chitosan, the liposome has an antibacterial property. Ferulic acid can scavenge free radicals, has higher antioxidant activity, and has the effect of protectingthe skin.

Description

technical field [0001] The invention relates to a liposome-containing nanofiber facial mask and a preparation method thereof, belonging to the field of cosmetic formulations. The invention adopts the nanofiber as the material of the facial mask, which improves the use comfort and the skin's absorption of the essence. In addition, liposomes encapsulating the active ingredients are added to the essence to slowly release the active ingredients to the skin. Background technique [0002] Along with the raising of my country's economic development and people's living standards, people pay more and more attention to skin care, especially the skin of the face. As one of the important cosmetics for facial skin care, facial mask has the characteristics of easy to carry, simple and effective operation, and is favored by consumers in general. Wet tissue sheet masks, which account for more than 80% of the mask market sales, are based on non-woven fabrics and absorb a certain amount o...

Claims

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Application Information

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IPC IPC(8): A61K8/86A61K8/73A61K8/34A61K8/63A61K8/365A61K8/81A61K8/02A61K8/14A61Q19/00A61Q17/00
CPCA61K8/86A61K8/736A61K8/34A61K8/63A61K8/365A61K8/8129A61K8/0212A61K8/14A61Q19/00A61Q17/005
Inventor 刘颖王冀
Owner JIANGSU JICUI ADVANCED POLYMER MATERIAL RES INST CO LTD
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