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A kind of ferric oxide nanometer magnetic particle array assembly structure and assembly method

A technology of ferroferric oxide and nano-magnetism, which is applied in the field of DNA nanometer

Active Publication Date: 2022-03-08
NANJING UNIV OF POSTS & TELECOMM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there is still no one-dimensional nanomagnetic particle array structure based on DNA tiles technology that can simulate the magnetosome array in magnetotactic bacteria.

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  • A kind of ferric oxide nanometer magnetic particle array assembly structure and assembly method
  • A kind of ferric oxide nanometer magnetic particle array assembly structure and assembly method
  • A kind of ferric oxide nanometer magnetic particle array assembly structure and assembly method

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Embodiment Construction

[0030] The present invention will be further described in detail below in conjunction with the examples.

[0031] The biotin-modified connecting chain, N1, N2, N3, S1 and S2 chains used in the following examples were all purchased from Shanghai Sangon Bioengineering Co., Ltd., and ferric iron tetroxide magnetic particles modified with streptavidin Purchased from Nanjing Dongna Biotechnology Co., Ltd.

[0032] like figure 1 Shown is a schematic diagram of the structure of the assembled ferric oxide nano-magnetic particle array of the present invention. The assembly method of the ferroferric oxide nanomagnetic particle array structure is based on the DNAtiles method, by setting a specific capture strand 15 on the DNA tiles structure ribbon-likeDNA nanostructures (RDN) and linking it with a biotin-modified linker strand 16 at the 3' end The combination transfers the connecting chain 16 to the surface of the RDN 13, thereby forming a biotin-modified RDN structure 18 with a speci...

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Abstract

The invention discloses an assembly structure and an assembly method of an array of iron ferric oxide nano-magnetic particles, comprising a DNA tiles structure ribbon-like DNA nanostructures (RDN) and a one-dimensional array of ferric iron tetroxide nano-magnetic particles with specific linking chains. The surface of the RDN is provided with a capture chain, the surface of the ferroferric oxide nano-magnetic particle is combined with a connecting chain, and the capturing chain and the connecting chain are complementary. The present invention is based on the DNA tiles method, by arranging a specific connecting chain on the DNA tiles self-assembly structure RDN and combining it with ferroferric oxide nano-magnetic particles, so that the specific connecting chain is transferred to the ferroferric oxide nano-magnetic particles The surface of the particles, and then form a one-dimensional nanomagnetic particle array with specific linkage chains.

Description

technical field [0001] The invention relates to the field of DNA nanotechnology, in particular to an assembly structure and an assembly method for assembling a ferric oxide nanometer magnetic particle array. Background technique [0002] Due to the magnetic properties and uniform size of metal particles, as well as unique chemical and biological activities, magnetic nanoparticles have potential applications in the fields of nanoelectronics, nanophotonics, and biomedicine. [0003] Magnetic nanoparticles are able to recognize non-parallel base pairs, so DNA can be used as part of building nanostructures. For example, DNA can modify and functionalize many different types of nanomaterials, including metals (eg, gold and silver), semiconductors (eg, quantum dots), and nanomagnetic materials (eg, ferromagnetic particles). DNA-functionalized nanomagnetic particles have received extensive attention from researchers. By controlling nanoparticles to carry nanomagnetic particles, ma...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C01G49/08B82Y40/00
CPCC01G49/08B82Y40/00C01P2004/64C01P2004/04
Inventor 晁洁舒展逸汪联辉
Owner NANJING UNIV OF POSTS & TELECOMM