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Ferroferric oxide nano magnetic particle array assembly structure and assembly method thereof

A kind of iron tetroxide and nano-magnetic technology, applied in the field of DNA nanometer

Active Publication Date: 2021-03-09
NANJING UNIV OF POSTS & TELECOMM
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there is still no one-dimensional nanomagnetic particle array structure based on DNA tiles technology that can simulate the magnetosome array in magnetotactic bacteria.

Method used

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  • Ferroferric oxide nano magnetic particle array assembly structure and assembly method thereof
  • Ferroferric oxide nano magnetic particle array assembly structure and assembly method thereof
  • Ferroferric oxide nano magnetic particle array assembly structure and assembly method thereof

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Embodiment Construction

[0030] The present invention will be further described in detail below in conjunction with the examples.

[0031] The biotin-modified connecting chain, N1, N2, N3, S1 and S2 chains used in the following examples were all purchased from Shanghai Sangon Bioengineering Co., Ltd., and ferric iron tetroxide magnetic particles modified with streptavidin Purchased from Nanjing Dongna Biotechnology Co., Ltd.

[0032] Such as figure 1 Shown is a schematic diagram of the structure of the assembled ferric oxide nano-magnetic particle array of the present invention. The assembly method of the ferroferric oxide nanomagnetic particle array structure is based on the DNAtiles method, by setting a specific capture strand 15 on the DNA tiles structure ribbon-likeDNA nanostructures (RDN) and linking it with a biotin-modified linker strand 16 at the 3' end The combination transfers the connecting chain 16 to the surface of the RDN 13, thereby forming a biotin-modified RDN structure 18 with a sp...

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Abstract

The invention discloses a ferroferric oxide nano magnetic particle array assembly structure and an assembly method thereof; the ferroferric oxide nano magnetic particle array assembly structure comprises a DNA tiles structure ribbon-like DNA nanostructures (RDN) and a one-dimensional ferroferric oxide nano magnetic particle array with a specific connecting chain, the surface of RDN is provided with a capture chain, the surface of the ferroferric oxide nano magnetic particles is combined with a connecting chain, and the capture chain and the connecting chain are complementary. On the basis of aDNA tiles method, the specific connecting chain is arranged on a DNA tiles self-assembly structure RDN to be combined with ferroferric oxide nano magnetic particles, so that the specific connecting chain is transferred to the surfaces of the ferroferric oxide nano magnetic particles, and then a one-dimensional nano magnetic particle array with the specific connecting chain is formed.

Description

technical field [0001] The invention relates to the field of DNA nanotechnology, in particular to an assembly structure and an assembly method for assembling an array of iron ferric oxide nanometer magnetic particles. Background technique [0002] Magnetic nanoparticles have potential applications in nanoelectronics, nanophotonics, and biomedicine due to their magnetic properties and uniform size as well as unique chemical and biological activities. [0003] Magnetic nanoparticles can recognize non-parallel base pairs, so DNA can be used as part of building nanostructures. For example, DNA can modify and functionalize many different types of nanomaterials, including metals (such as gold and silver), semiconductors (such as quantum dots), and nanomagnetic materials (such as ferromagnetic particles). DNA-functionalized magnetic nanoparticles have attracted extensive attention from researchers. By controlling nanoparticles to carry nanomagnetic particles, it is possible to pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C01G49/08B82Y40/00
CPCC01G49/08B82Y40/00C01P2004/64C01P2004/04
Inventor 晁洁舒展逸汪联辉
Owner NANJING UNIV OF POSTS & TELECOMM