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Manufacturing equipment of pharmaceutic adjuvants

A technology for manufacturing equipment and pharmaceutical excipients, which is applied in the field of manufacturing equipment for pharmaceutical excipients, can solve problems such as freezing point depression, high maintenance costs, uneven adhesion to tower walls, etc., and achieve fast homogenization speed, high safety, and distribution uniform effect

Pending Publication Date: 2021-03-16
江苏优扬药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also various disadvantages, first, the freezing point is lowered; second, the pre-batching operation, product switching is easy to mix; third, the fine powder of the product is unevenly bonded to the tower wall, the maintenance cost is high, and it is easy to cause dust explosions, etc. safe question

Method used

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  • Manufacturing equipment of pharmaceutic adjuvants
  • Manufacturing equipment of pharmaceutic adjuvants
  • Manufacturing equipment of pharmaceutic adjuvants

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A manufacturing equipment for pharmaceutical excipients, mainly used to prepare pharmaceutical excipients stearic acid and cetostearyl alcohol; including a raw material tank, a delivery pump, a cooling tower 7, a separator 11, a fan 10 and a cooler 9; the The air outlet at the top of the cooling tower 7 is connected to the blower fan 10 through the separator 11, and the fan 10 is connected to the lower air inlet of the cooling tower 7 through the cooler 9 to form an air circulation; the bottom of the cooling tower is provided with a discharge port 8; A nozzle is installed inside the tower 7 through a pipeline, and the nozzle is connected to the raw material tank through a delivery pump.

[0021] The raw material in the raw material tank is transported to the cooling tower 7 through the nozzle, dispersed into liquid droplets and falls down; , forming a cycle. The falling raw material droplets and the cold air countercurrently contact and immediately solidify into solid ...

Embodiment 2

[0024] The equipment described in Example 1 was used to prepare small particles of cetostearyl alcohol as a pharmaceutical adjuvant: as shown in Table 1 below:

[0025] Table 1

[0026]

Embodiment 3

[0028] Adopt the equipment described in embodiment 1 to prepare stearic acid granules: specifically as shown in table 1 below:

[0029] Table 2

[0030]

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Abstract

The invention discloses manufacturing equipment of pharmaceutic adjuvants. The manufacturing equipment is mainly used for preparing the pharmaceutic adjuvants including stearic acid and cetostearyl alcohol. The device comprises a raw material tank, a delivery pump, a cooling tower, a separator, a fan and a cooler, an air outlet in the top of the cooling tower is connected with a draught fan through a separator, the draught fan is connected with an air inlet in the lower portion of the cooling tower through a cooler, and air circulation is formed. A discharge hole is formed in the bottom of thecooling tower; and a spray head is mounted in the cooling tower through a pipeline, and is connected with the raw material tank through a conveying pump. The material formula in the equipment productmanufacturing process is continuous and adjustable, and pre-batching is not needed; the production process is high in safety, and the separator in front of the fan basically has no fine powder.

Description

technical field [0001] The invention relates to a manufacturing equipment of pharmaceutical auxiliary materials, which is especially suitable for the preparation of small granular stearic acid and cetostearyl alcohol. Background technique [0002] Small granular cetostearyl alcohol for medicinal use is widely used in the pharmaceutical industry because of its large specific surface area and easy mixing with other materials. At present, the production process of pharmaceutical grade cetostearyl alcohol is mainly to melt cetostearyl alcohol and stearyl alcohol according to the formula, mix them evenly, and then cool them through a granulator to make small beads, hemispheres or flakes, etc. Shaped products. This process has four major disadvantages. First, the mixing of two different materials will lower the freezing point, causing summer products to stick easily, especially for small granular products; second, in order to prevent materials from sticking, the particle size can...

Claims

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Application Information

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IPC IPC(8): B01J2/04A61J3/00
CPCA61J3/00B01J2/04
Inventor 祝红元张纪赵继明罗勇
Owner 江苏优扬药业有限公司
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