Oral care gel with lasting helicobacter pylori resisting effect and preparation method thereof

Abstract

The invention relates to an oral gel, in particular to an oral care gel with a lasting helicobacter pylori resisting effect. The oral care gel comprises the following components in percentage by mass:0.05%-0.2% of a bactericide, 1%-5% of a surfactant, 5%-1.5% of carboxymethyl cellulose, 0.1%-0.3% of ammonium polyacryloyldimethyl taurate, 0.1%-0.5% of isopropyl myristate, 0.05%-0.5% of glycyrrhizic acid, 0.05%-0.3% of menthol, 0.5%-5% of xylitol, trace of nano platinum, and the balance of purified water. A preparation method comprises the following steps that the purified water is divided intotwo parts according to a formula, one part is added into carboxymethyl cellulose and ammonium polyacryloyldimethyl taurate, and stirring and dissolving are conducted for 30-40 minutes until the purified water becomes transparent gel, so that a system A is obtained; the surfactant, the glycyrrhizic acid, the xylitol and the menthol are added into the other part of purified water, and stirring is conducted at the temperature of 40-50 DEG C until dissolution is completed to obtain a system B; the bactericide, nano platinum and isopropyl myristate are added into the system B, and uniform stirringis conducted to obtain a system C; and the system C is added into the system A under a stirring condition, and uniform mixing is conducted to obtain the oral care gel capable of continuously acting.

Description

technical field [0001] The invention relates to oral care, in particular to an oral care gel against Helicobacter pylori. Background technique [0002] Helicobacter pylori is a gram-negative bacterium with a spiral shape, microaerophilicity, and very harsh growth conditions. It is a known microbial species that can survive in the stomach and mouth. Since the 1980s, domestic and foreign scholars have continuously isolated and cultured Helicobacter pylori in the stomachs of clinical patients with gastritis and gastric ulcer, and confirmed that it is the main pathogenic factor of various digestive system diseases, which has attracted widespread attention. It has revolutionized the concepts of the occurrence and development of diseases such as chronic gastritis, peptic ulcer and gastric cancer. In 2017, Helicobacter pylori has been listed as a class I carcinogen by the World Health Organization. It is internationally recognized as a pathogenic bacteria of gastric ulcer, duodena...

AI Technical Summary

Problems solved by technology

However, anti-Helicobacter pylori toothpaste and mouthwash products currently on the market have weak bactericidal ability, and their bactericidal action time is short, so they can only work during brushing and rinsing. After cleaning the mouth, the bacteria in the mouth grow rapidly again. No long-lasting antibacterial effect

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