44results about How to "Prevent stomach ulcers" patented technology

The invention discloses lactation compound feed for sows and a preparation method thereof. The lactation compound feed for sows is made from wheat, corn in northeast China, 46% soybean meal, soybean hull, calcium hydrophosphate, rice bran oil, liquid phytase, liquid compound enzyme, limestone flour, salt, 65% lysine, threonine, 60% choline chloride, antioxidant, plasma protein, potassium chloride, magnesium sulfate, vitamin prefix, and trace mineral premix. The preparation method include: weighing all materials by percent weight, and adding the materials into a crusher for crushing under the crushed size of 25-40 mesh; and adding the crushed materials into a pelletizer to make pellets at 85 DEG C with gelatinization degree reaching more than 90%. The lactation compound feed for sows has the advantages that the lactation compound feed for sows meets requirements of nursing sows for nutrition and is high in palatability, immunity, milk yield and milk quality are increased for the sows, and productivity of piglets is further improved.

The invention relates to an ultra-low calorie health-care type soluble drink mate and a preparation method thereof. The drink mate comprises the following food raw materials and food additives in percentage by weight: soyabean lecithin, sodium casseinate, grape seed extract (containing more than or equal to 30 percent of grape polyphenol and more than or equal to 60 percent of oligomeric proanthocyanidins in percentage by mass), stevioside containing more than or equal to 80 percent of RA, sodium stearoyl lactylate, molecular distilled monoglyceride, sodium citrate, disodium hydrogen phosphate, sodium alginate, carrageenan, edible essence, silicon dioxide, and the like. The preparation method comprises the following steps: blending the materials, dissolving, emulsifying, homogenizing, spray drying, cooling regularly, sieving, metering and packaging. The invention has simple process, stable product quality and high nutritional value. The ultra-low calorie health-care type soluble drinkmate integrates the nutritional values of the soyabean lecithin, the stevioside containing more than or equal to 80 percent of RA, the sodium casseinate and the grape seed extract, has unique taste, smooth and fine mouthfeel and thick fragrance, does not contain trans fatty acid and is a novel ultra-low calorie health-care type soluble drink mate.

The novel positively charged pro-drugs of ibuprofen in the general formula (I) ''Structure 1'' were designed and synthesized. The compounds of the general formula (I) ''Structure 1'' indicated above can be prepared from functional derivatives of ibuprofen, (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl 2-(p-isobutylphenyl) propionate.AcOH, diffuses through human skin -250 times faster than ibuprofen itself and -125 times faster than ethyl 2-(p-isobutylphenyl) propionate. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any ibuprofen-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of ibuprofen, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enable the ibuprofen to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of ibuprofen.

Large-pig health-care feed promoting intake relates to the technical field of animal feed and is prepared from the following raw materials in parts by weight: 350 parts of puffed bean powder, 45 parts of rice flour, 20 parts of bran, 5 parts of shrimp shell, 3 parts of a premix, 25 parts of corn-flour germ bran, 15 parts of greenfeed, 1 part of bamboo shoot, 20 parts of rice wine, 20 parts of sweet potato powder, 15 parts of green alga powder, 5 parts of dry ginger powder, 3 parts of honey-fried licorice root, 2 parts of black tea, 5 parts of kumquat, 2 parts of silkworm chrysalis powder, 5 parts of fish meal, 5 parts of grease and 8 parts of a traditional Chinese medicine additive. Compared with conventional feed, the compositions of the feed comprise the traditional Chinese medicine additive which cooperates with a feed carrier for playing a role, so that the feed helps to satisfy normal nutrition demands of large pigs, also gives play to fortify stomach and promote digestion, helps to increase the intake of pigs, avoid appearance of gastric ulcer of pigs and improve immunity of large pigs, and also is capable of promoting growth of large pigs; and the feed is free of toxic and side effects, does not generate drug resistance, does not pollute environment, helps to increase body immunity, and is fast in effectiveness and low in price.

The invention provides a gastrohelcosis-prevention herbal tea formula. In the formula, gastrohelcosis-prevention herbal tea consists of the components in parts by weight: 10-13 parts of radix bupleuri, 14-15 parts of radix paeoniae alba, 8-12 parts of fructus aurantii, 10-15 parts of mangnolia officinalis, 11-15 parts of fried rhizoma cyperi, 12-14 parts of fingered citron, 12-15 parts of herbal leaven, 3-6 parts of liquorice, 7-11 parts of dendrobe, 8-10 parts of radix cyathulae, 11-13 parts of rhizoma corydalis, 4-6 parts of cardamom and 4-6 parts of pinellia ternate. The herbal tea prepared according to the formula disclosed by the invention can effectively nourish stomach and prevent gastrohelcosis and can treat the gastrohelcosis to a certain extent.

The invention discloses new uses of a plant extract stachyose in hangover alleviating, wherein the stachyose is a stachyose product extracted from stachys sieboldii, stachys floridana schuttl.ex benth, stachys sieboldii, trumpetweed, soybean or rehmannia. According to the present invention, ordinary food, health food or medicine having a hangover alleviating function can be prepared by using the stachyose, and the hangover alleviating product comprises 1.0-100% of stachyose, 0.0-50% of a lobed kudzuvine root extract and 0.0-50% of a ethanol oxidase, can further comprises other additives, can be used before or after wine drinking, provides effects of protection of gastrointestinal tract, reduction of damage on liver by ethanol, and comprehensive adjustment of human internal environment, and is a health partner for drinkers.

The novel positively charged pro-drugs of aryl- and heteroarylacetic acids in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of tolmetin, zomepirac, etodolac, amfenac, bromofenac, alclofenac, fenclofenac, acemetacin, indomethacin, sulindac, fentiazac, lonazolac, bendazac, 6MNA, ibufenac, and related compounds, (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The results suggest that the pro-drugs diffuses through human skin 100 times faster than does tolmetin, zomepirac, etodolac, amfenac, bromofenac, alclofenac, fenclofenac, acemetacin, indomethacin, sulindac, fentiazac, lonazolac, bendazac, or related compounds. It takes 2-4 hours for tolmetin, zomepirac, etodolac, amfenac, bromofenac, alclofenac, fenclofenac, acemetacin, indomethacin, sulindac, fentiazac, lonazolac, bendazac, 6MNA, ibufenac, and related compounds to reach the peak plasma level when they are taken orally, but these prodrugs only took about 40-50 minutes to reach the peak plasma level when they are taken transdermally. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any NSAIAs-treatable conditions in humans or animals. The prodrugs can be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of NSAIAs, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis.

The invention relates to an oral gel, in particular to an oral care gel with a lasting helicobacter pylori resisting effect. The oral care gel comprises the following components in percentage by mass:0.05%-0.2% of a bactericide, 1%-5% of a surfactant, 5%-1.5% of carboxymethyl cellulose, 0.1%-0.3% of ammonium polyacryloyldimethyl taurate, 0.1%-0.5% of isopropyl myristate, 0.05%-0.5% of glycyrrhizic acid, 0.05%-0.3% of menthol, 0.5%-5% of xylitol, trace of nano platinum, and the balance of purified water. A preparation method comprises the following steps that the purified water is divided intotwo parts according to a formula, one part is added into carboxymethyl cellulose and ammonium polyacryloyldimethyl taurate, and stirring and dissolving are conducted for 30-40 minutes until the purified water becomes transparent gel, so that a system A is obtained; the surfactant, the glycyrrhizic acid, the xylitol and the menthol are added into the other part of purified water, and stirring is conducted at the temperature of 40-50 DEG C until dissolution is completed to obtain a system B; the bactericide, nano platinum and isopropyl myristate are added into the system B, and uniform stirringis conducted to obtain a system C; and the system C is added into the system A under a stirring condition, and uniform mixing is conducted to obtain the oral care gel capable of continuously acting.

A mixed nutritious soup has a totally different making method compared with the existing making methods of a mixed nutritious steamed bread, a steamed stuffed bun, a dumpling, a wonton, a sesame seed cake, a fine rice noodle, a coarse rice noodle and a rice cake and contains many anticancer substances inside so as to prevent diseases and extend life, for example, green tea contains tea polyphenols, anticancer fluoride for sterilization, tea canning for preventing ruptured blood vessel and antioxygen free radical for reducing tumor and arteriosclerosis, lotus seed can relieve mental strain and strengthen the kidneys, prevent aging and extend life, millet can keep people calm, tomato can prevent various cancers, and spirulina contains 18 amino acids, 11 microelements and 9 vitamins and can prevent various diseases. Various diseases are prevented and treated through food therapy.

The invention discloses a compound probiotic preparation for killing helicobacter pylori, and a preparation method thereof. The compound probiotic preparation comprises isomaltooligosacharide, lactitol, inulin, resistant dextrin, apple concentrated powder, acerola cherry concentrated powder, galactooligosaccharide, xylooligosaccharide, stachyose, first lactic acid bacteria powder, lactobacillus plantarum powder, lactobacillus reuteri LR-G100, second lactic acid bacteria powder, bifidobacterium animalis BB-12, ascorbyl palmitate and sucralose. The invention further discloses a preparation method of the compound probiotic preparation. The adopted raw materials are simple and easy to obtain, the preparation method is easy to operate, and the obtained compound probiotic preparation can effectively inhibit growth of helicobacter pylori and kill the helicobacter pylori, so that diseases such as duodenal ulcer, gastric ulcer and gastric cancer can be effectively treated and prevented.

The invention relates to a water-soluble ibuprofen prodrug with high skin penetration rate and positive charges. The invention discloses the application of a compound shown in a structural formula 1 to preparation of a medicament suitable for transdermal delivery and for treating the conditions that can be treated by ibuprofen, and the application of the compound shown in the structural formula 1 to preparation of an aerosol medicament for treating asthma. The invention also discloses the application of a pharmaceutical composition for transdermal delivery and containing the compound shown in the structural formula 1, the application thereof to preparation of a medicament suitable for transdermal delivery and for treating the conditions that can be treated by ibuprofen, and the application of the pharmaceutical composition to preparation of an aerosol medicament for treating asthma. The invention also discloses a transdermal therapeutic system, which comprises the compound shown in the structural formula 1 or its composition, and a usage method of the transdermal therapeutic system.

The novel positively charged pro-drugs of diflunisal, salicylsalicylic acid, and salicylic acid in the general formula(1) 'Structure 1' and general formula(2) 'Structure 2' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' or general formula(2) 'Structure 2' indicated above can be prepared from functional derivatives of diflunisal, salicylsalicylic acid, or salicylic acid, (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs, but also bonds to the negative charge on the phosphate head group of membranes and pushes the pro-drug into the cytosol. The results suggest that the pro-drug, diethylaminoethyl 5-(2,4-difluorophenyl) salicylate. AcOH diffuses through human skin ~150 times faster than does diflunisal itself. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any diflunisal, salicylsalicylic acid, or salicylic acid-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of diflunisal, salicylsalicylic acid, or salicylic acid, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enables diflunisal, salicylsalicylic acid, or salicylic acid to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of diflunisal, salicylsalicylic acid, or salicylic acid.

The invention discloses a poria cocos jelly with aging delaying effect and a preparation method thereof, and relates to the technical field of preparation of poria cocos jelly. The poria cocos jelly is prepared from the following raw materials in parts by weight: 25 to 30 parts of poria cocos, 18 to 23 parts of radix polygoni multiflori, 20 to 25 parts of radix bupleuri, 22 to 27 parts of fructusschisandrae chinensis, 8 to 12 parts of semen coicis, 17 to 22 parts of herba ecliptae prostrate, 6 to 10 parts of mulberry fruit, 15 to 20 parts of herba dendrobii, and 5 to 8 parts of honey. The poria cocos jelly has the advantages that the poria cocos jelly is prepared from multiple types of natural plant medicines; the functional ingredients of saponin, lactone, flavone, active polysaccharides, amino acids and the like in the fructus schisandrae chinensis, the herba ecliptae prostrate, the herba dendrobii, the radix bupleuri, the radix polygoni multiflori and other raw materials are extracted by a water extracting method, then the semen coicis powder, the poria cocos powder, the mulberry fruit powder and the like are added into an extracting solution to mix and decoct, and the honey isused for flavoring; the prepared poria cocos jelly is used for clearing free radicals produced by metabolism of the human body, adjusting the internal secretion, improving the content of hormone, andreducing blood fat, blood lipid and blood glucose, the self-immunity function is enhanced, the aging rate of skins and organs is relieved, and the aging of the human body is delayed; the mouth feel of the poria cocos jelly is good, and the discomfort and any side effect are avoided even if the poria cocos jelly is taken for a long time.

The invention provides a preparation method of traditional Chinese medicine pills capable of strengthening the spleen and harmonizing the stomach and relates to the technical field of preparation of traditional Chinese medicines. According to the preparation method of traditional Chinese medicine pills capable of strengthening the spleen and harmonizing the stomach, the traditional Chinese medicine pills are prepared from the following raw materials in parts by weight: 20-40 parts of rhizoma atractylodis macrocephalae, 15-30 parts of radix aucklandiae, 20-30 parts of wine-processed rhizoma coptidis, 20-40 parts of poria cocos, 15-20 parts of radix ginseng, 10-20 parts of medicated leaven, 20-25 parts of dried tangerine peel, 10-20 parts of safranine, 15-25 parts of malt, 10-15 parts of fructus crataegi and 15-25 parts of rhizoma Pinelliae preparatum. The rhizoma atractylodis macrocephalae has the effects of strengthening the spleen, tonifying Qi and stopping sweating and has a bidirectional regulation effect on a gastrointestinal system; the radix aucklandiae has the effects of promoting Qi circulation to relieve pain, invigorating the spleen to promote digestion, promoting gastrointestinal peristalsis and expanding bronchial smooth muscles; the poria cocos has the effects of removing dampness and promoting diuresis, tonifying the spleen, calming a heart and being capable of preventing gastric ulcer; and various medicinal materials are ground into powder and then prepared into pills for administration, pharmacological structures are not damaged, the curative effect of medicines is ensured, the treatment effect is improved, and the pills are more conveniently taken by a patient and worthy of vigorous popularization.

The invention discloses a bone peptide extracting solution and a preparation method and application thereof in treatment of bone marrow injury. A high-content bone peptide extract is obtained by mixing and extracting acid and alkali and enzymes to prevent gastric mucosa ulcer, suppress blood pressure rise, improve bone strength, promote skin collagen metabolism to delay aging, promote the absorption of minerals, and also to resist hypertension, prevent and treat osteoarthritis and osteoporosis, treat gastric ulcer and other diseases, and resist aging and oxidation. Most importantly, the peptide extract can effectively prevent and treat bone marrow suppression and other adverse effects easily occurring in the current cancer chemotherapy, effectively prevent and treat bone marrow injury peripheral blood and bone marrow hematopoietic function, and improve bone marrow hyperplasia.

The novel positively charged pro-drugs of diclofenac in the general formula(1) 'Structure 1' were designed and synthesized. The compounds of the general formula(1) 'Structure 1' indicated above can be prepared from functional derivatives of diclofenac (for example acid halides or mixed anhydrides), by reaction with suitable alcohols, thiols, or amines. The positively charged amino groups of these pro-drugs not only largely increases the solubility of the drugs in water, but also bonds to the negative charge on the phosphate head group of membranes and push the pro-drug into the cytosol. The experiment results suggest that the pro-drug, diethylaminoethyl 2[(2,6-dichlorophenyl)amino]benzene acetate.AcOH diffuses through human skin ~250 times faster than do 2[(2,6-dichlorophenyl)amino]benzene acetic acid (diclofenac) and ethyl 2[(2,6-dichlorophenyl)amino]benzene acetate. In plasma, more than 90% of these pro-drugs can change back to the drug in a few minutes. The prodrugs can be used medicinally in treating any diclofenac-treatable conditions in humans or animals and be administered not only orally, but also transdermally for any kind of medical treatments and avoid most of the side effects of diclofenac, most notably GI disturbances such as dyspepsia, gastroduodenal bleeding, gastric ulcerations, and gastritis. Controlled transdermal administration systems of the prodrug enables the diclofenac to reach constantly optimal therapeutic blood levels to increase effectiveness and reduce the side effects of diclofenac.

The invention discloses poria cocos honey capable of tranquilizing mind and promoting sleeping and a preparation method thereof and relates to the technical field of health foods. The poria cocos honey is prepared from the following raw materials in parts by weight: 18 to 26 parts of mulberry fruits, 20 to 28 parts of semen ziziphi spinosae, 18 to 26 parts of muskmelon seeds, 22 to 30 parts of white poria cocos, 22 to 30 parts of bighead atractylodes rhizome, 20 to 28 parts of radix polygalae, 17 to 25 parts of cortex albiziae, 15 to 23 parts of fructus citri and 1000 parts of honey. The poriacocos honey takes honey as a carrier; components including mulberry fruits, semen ziziphi spinosae, muskmelon seeds, white poria cocos, bighead atractylodes rhizome, radix polygalae, cortex albiziae,fructus citri and the like are added, and radix polygalae is immersed in rice washing water and then is collected, so that the acrid drug property of radix polygalae can be reduced and the effects ofclearing away heat and moistening intestines are realized; after all the raw materials are extracted, the extracts are added into the honey, and ultrasonic mixing is carried out so that medical components of the honey are not reduced; all the traditional Chinese medicine raw materials are mutually compatible to commonly realize the effects of tonifying spleen and moistening lung, and tranquilizing mind and promoting sleeping; after the traditional Chinese medicine raw materials are added into the honey, the efficacy can be improved; and the poria cocos honey can be used for alleviating headache, dizziness and fatigue, alleviating symptoms including tension, anxiety, depression, neurosis and the like, and thus improving the sleeping quality.

The present invention relates to the technical field of food processing and discloses a health-care ginger tablet and a preparation method thereof. The health-care ginger tablet comprises the following raw materials in parts by weight: 400-500 parts of fresh gingers, 90-100 parts of sucrose, 130-150 parts of edible salt, 170-200 parts of edible vinegar, 20-30 parts of radix morindae officinalis, 15-22 parts of semen allii tuberosi, 10-20 parts of rhizoma polygonati, 5-10 parts of Chinese magnoliavine fruits, 10-18 parts of semen cuscutae, 5-10 parts of lily bulbs, 10-16 parts of radix astragali, 4-10 parts of lucid ganoderma, 8-14 parts of dendrobium nobile stems, 6-12 parts of poria cocos, 7-14 parts of radix salviae miltiorrhizae and 6-12 parts of licorice. The prepared health-care ginger tablet is good in taste and also has effects on preventing oxidation and preventing aging.

The invention provides medicinal liquor and a preparation method thereof, and relates to the field of medicinal liquor preparation, and the preparation process of the medicinal liquor comprises the following steps: SP1, selecting moringa oleifera leaves, clove, rhizoma polygonati and dandelion as raw materials, and cleaning; sP2, airing the cleaned moringa oleifera leaves, cloves, rhizoma polygonati and dandelions; sP3, crushing moringa oleifera leaves, cloves, rhizoma polygonati and dandelions; sP4, soaking the medicinal liquor; sP5, filtering the medicinal liquor; and SP6: packaging, storing and transporting the medicinal liquor. The moringa oleifera leaves are used as main raw materials, the clove, the rhizoma polygonati and the dandelion are used as auxiliary raw materials, the clove is beneficial to preventing gastric ulcer and protecting intestines and stomach, the clove has the effects of inhibiting and killing bacteria, and then the rhizoma polygonati can treat dry eyes, dizziness, inadequate sleep, insomnia, dreaminess and other diseases caused by liver yin deficiency and mainly has the effects of nourishing yin of the liver and the kidney and promoting digestion. The dandelion has the effects of clearing away heat and toxic materials, eliminating carbuncle and removing stasis, and promoting diuresis and treating stranguria, the medicinal liquor produced through auxiliary materials has more effects, and the selected liquor is suitable for brewing medicinal materials, so that the produced liquor has better medicinal properties.

The invention relates to water-soluble ketoprofen with a high skin penetration speed and positive charges and a prodrug of a related compound. The invention discloses a compound shown in a structural formula 1, a preparation method of the compound, and application of the compound in preparing a medicine for treating the disease of which the state can be treated through ketoprofen or fenoprofen for people or animals. The invention further discloses a skin penetration treatment application system containing the compound.